Computational & Experimental Stem Cell Biology. A member of the Department of Biomedical Engineering at Johns Hopkins University.
Baltimore, MD
Joined August 2016
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Cahan Lab | at JHMI retweeted
The second major chunk of my Ph.D. is now online in Genome Biology! Brief recap: 🧵
genomebiology.biomedcentral.…
Cahan Lab | at JHMI retweeted
We are looking for new postdocs to join our team. Positions are fully funded and you can pursue your interest in technology development, biological questions, or understanding disease.
jobrxiv.org/job/johns-hopkin…
Cahan Lab | at JHMI retweeted
Submit your research to Stem Cell Reports—the premier society journal for stem cell research and an open access forum communicating basic discoveries in stem cell research, in addition to translational and clinical studies @isscr @martinperajax hubs.li/Q01t6Bgt0
Cahan Lab | at JHMI retweeted
Friends, Im excited to share my work linking #GRNs with dynamic #signals via #agents. The #multiscale GARMEN showed how a master GRN can lead to different #tissue structures. We successfully tested signal and transcriptomic perturbation outcomes in vitro
bit.ly/3T41hES
Cahan Lab | at JHMI retweeted
We are pleased to announce the call for papers for a new special issue on the clinical translation of PSCs, guest edited by Drs. Shinya Yamanaka and Kazuto Takayama of @CiRA_KU_E . To learn more and sumit - bit.ly/3V1AmLS. @ISSCR @martinperaJAX @CellPress
Cahan Lab | at JHMI retweeted
Single-cell papers that make the count matrices and cell type classifications easily available are 100% more likely to be cited by me. Cell type-specific signature genes are a bonus.
Cahan Lab | at JHMI retweeted
Four permanent posts in interdisciplinary research at the Living Systems Institute - uniting maths, physics, and biology. Apply here; lsi.exeter.ac.uk/join-us/job…
Cahan Lab | at JHMI retweeted
Entropy sorting of single cell RNA sequencing data reveals the inner cell mass in the human pre-implantation embryo biorxiv.org/content/10.1101/…
Cahan Lab | at JHMI retweeted
Two new pre-prints out today from Srivastava lab where we apply single cell chromatin accessibility and transcriptomics to define mechanisms underlying congenital heart defects arising from genetic and environmental perturbations, respectively.
Mine:
biorxiv.org/content/10.1101/…
Cahan Lab | at JHMI retweeted
Our latest work looking at maturation across organs is out now in J. Comp Bio! Great job Sandeep, Hideki, and @sean_murphy50.
doi.org/10.1089/cmb.2021.034…
Cahan Lab | at JHMI retweeted
Call for papers for a @stemcellreports special issue: Computational systems biology, guest edited by Barbara Treutlein @TreutleinLab and Patrick Cahan @cahanLab. Submit your paper before April 10, 2022 @ISSCR @martinperaJAX
hubs.li/Q013xlxt0
Cahan Lab | at JHMI retweeted
Decoding the function of Bivalent Chromatin in development and cancer. Bivalency does NOT poise genes for rapid activation BUT protects promoters from de novo DNA methylation. Bivalent domains have a function after all!
tinyurl.com/375t57zr
Cahan Lab | at JHMI retweeted
Congrats to lab alum chris cherry on the publication of his thesis work. Thanks to computational collaborators @FertigLab @cahanLab and @GarmireGroup. In this work, we show that it's not just which cells are in the tissue/wound or around the biomaterial but how they communicate
Cellular signalling networks in the microenvironment of implanted biomaterial scaffolds can be computationally reconstructed from single-cell RNA-sequencing data of cells collected from the implantation site.
rdcu.be/crB2S
Cahan Lab | at JHMI retweeted
Twitter friends, do tune in to this exciting event organised by @cahanLab @PZandstra @ISSCR.
I will talk about a multiscale approach to link gene regulatory network interactions to tissue patterns.
@RAEngNews @VPH_Institute @StemCellBioEng @uniofleicester
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Cahan Lab | at JHMI retweeted
Co-organizers develop a program that focuses on the latest developments in the rapidly advancing field of computational #stemcell biology. Join us! #ISSCRDigital isscr.org/meetings-events/is… @OwenRackham @JayShin @morris_lab @mincle @cahanLab @PZandstra
Cahan Lab | at JHMI retweeted
Excited to share our latest work on liver growth + regeneration. Diverse hepatocytes carry out distinct functions, but it is still unclear which ones are the source of new hepatocytes. Yonglong Wei discovered that cells in zone 2 repopulate the liver.
science.sciencemag.org/conte…
Cahan Lab | at JHMI retweeted
The advantage of having a zoom thesis seminar is that friends from all over the globe can learn what I have been up to all these years!! My thesis seminar will be on Feb15 (Mon) at 9:30 AM (EST). If you would like to join me at the event, please DM me for details!
Cahan Lab | at JHMI retweeted
For you maturation and/or RNA-seq afficionados, check out this study directly comparing maturation trajectories in cardiomyocytes in vivo and in vitro. We hope this study can inform ongoing maturation efforts. biorxiv.org/content/10.1101/…
Cahan Lab | at JHMI retweeted
A great overview of the opportunities and barriers to computational stem cell research that require coordinated action across the stem cell field, bit.ly/3bxXVrF. @ISSCR @mincle @morris_lab @OwenRackham @martinperaJAX
