Scientist and Professor at University of Notre Dame; Father and Husband at House of Smith. opinions are my own.
Joined October 2014
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Special thanks to @FChrisBennett and @nachoriko for the wonderfully written primer on our new microglia cannibalism publication. It’s so amazing when such exceptional scientists write about our work!
Microglia can selectively clear neurons, but what else do they eat? @FChrisBennett & @nachoriko explore a #PLOSBiology study showing that #microglia also cannibalize other microglia, followed by microglial necroptosis Primer: plos.io/4f7sXEs Paper: plos.io/3Aj1JvE
For more information about the study, please see this thread: xitter.cf/cssmity/status/1636467…
Really excited about our new preprint from the lab about microglia lifespan and cannibalism. Congrats to Hannah Gordon for her hard work! Read more below about the story 👇🧵👇 @ZTSlab
biorxiv.org/content/10.1101/…
We are excited that our work describing microglia cannibalism is now officially in press! journals.plos.org/plosbiolog…
Stay tuned because we are on to the genetic mechanisms! 😀
Microglia cannibalism!!!!
Microglia are considered long lived, but @cssmity &co show that individual embryonic #microglia die within 3 days after clearing neural debris and are cannibalized by existing microglia, paradoxically leading to additional microglial death #PLOSBiology plos.io/3Aj1JvE
Come join us at Notre Dame!
Neuroscience faculty job alert! The University of Notre Dame is hiring 5 tenure-track positions in cellular, molecular, or computational neurobiology. Come be my colleague in a welcoming and inclusive environment. Please share! apply.interfolio.com/152596
Candidates working with various model systems, including non-mammalian models, are encouraged to apply!
We are seeking researchers who investigate the development, regeneration, and function of the nervous system, as well as the molecular and cellular mechanisms underlying health and disease, detection, and treatment.
The University of Notre Dame is hiring a cluster of 5 new Assistant Professors in Neuroscience starting this year, focused on cellular, molecular, or computational neurobiology.
Come be a colleague! More information here:
apply.interfolio.com/152596
Please share and retweet!
I am excited to get this project moving with @stevens1lab to find new microglia modifiers. I am also excited to be part of the larger group of collaborative people that are in the @ChanZuckerberg network!
💡 Innovation + 👩🏾🔬🧑🏼🔬 Collaboration = 🧠 Increased understanding of the brain
Meet 64 interdisciplinary teams working to expand our understanding of neuroscience + find treatments for neurodegenerative diseases czi.co/42K4IqJ
Finally, Jake made a personal dream come true...we somehow snuck in a Star Wars reference to our research! Next up, legos! media.giphy.com/media/UsmcxQ…
Jake's contribution to the lab was so important for our future work! In particular, he introduced calcium imaging to the lab, which opens up our ability to do circuit analysis (coming soon!)!