member of the capital deployment staff @GradientVC
San Francisco, CA
Joined January 2008
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Darian Shirazi retweeted
Churchill could have shortened WW2 by years if he had just “done a deal” with Hitler. George Washington could have done a deal to end the American Revolution. Zelenskyy is in good company.
“Size is the enemy of returns. It can work for a very small set of funds but it cannot work for most of them,” @AsafHoresh @Vintage_Inv
We agree @GradientVC 🚀
wsj.com/pro/venture-capital/…
Darian Shirazi retweeted
That's Lambda in the NVIDIA GTC Berlin keynote.
We're building with @NVIDIA on secure, efficient AI infrastructure, including an NVIDIA DSX MaxLPS proof of concept, plus support for Confidential Bare Metal and the NVIDIA OpenShell Reference Architecture.
#NVIDIAGTC
There's no stopping @WeAreLegora! Congrats @MaxJunestrand @jacsebl and the entire team on raising $550M at a $8.8B valuation from @GavinSBaker @Atreidesmgmt! What a milestone and thank you for having me as one of the first investors. To the moon!!! thenextweb.com/news/legora-s…
Darian Shirazi retweeted
Critical infrastructure is being run on software from the 1980s, says ASI CEO Phillip Buckendorf.
He explains how ASI uses AI to orchestrate complex systems like air traffic control and energy transmission bit.ly/47rtE9E
Darian Shirazi retweeted
At @GamowLabs, we are committed to solving rare disease. This means understanding the clinical impact of >9B possible mutations in the human genome.
Computational models like @GoogleDeepMind AlphaGenome, @arcinstitute Evo2, and @biohub ESM3 serve their purpose, but the only way to accomplish our mission is through large-scale collection of experimental data on variant effects.
The only way to collect these data is through robotic labs like ours, which historically have required deep expertise in automation engineering to scale, limiting velocity.
To solve this problem, we are building frameworks to enable AIs to drive our lab robots and just unveiled our first eval showing that we have some work to do!
Can frontier AI agents run a robotic wet lab?
We built LabRobotBench to test how they operate equipment, manage timing, and recover interrupted experiments. LabRobotBench allows models to steer a simulation based on our real wet-lab setup in Boulder, CO!
The best model tested, GPT 6.1 Sol, scores a 46% on our benchmark.
Improving on LabRobotBench implies better robotic control and spatial awareness, as well as biological reasoning.
read more in our latest blog post: gamowlabs.com/lab-robot-benc…
Darian Shirazi retweeted
While hundreds of billions have been spent teaching AI to manipulate words and generate videos, ASI builds AI systems that can manage and control critical physical infrastructure - where there is zero margin for error.
Today we announced our $325M Series C to scale America’s Engine: the automated nervous system keeping the country running.
Congrats on the launch! We're @GradientVC are excited to be an early backer of Vyb!
I launched the first image and video generation models at Google, and kept asking why all AI designs look the same.
AI has brought us the WORST era of design.
It made content creation effortless, but it also made 90% of it look painfully generic.
My co-founder and I spent 2 years building in stealth to change that.
Meet Vyb, the first AI design model that understands your taste like a designer would.
RT + comment your website URL and we’ll make your first design.
Huge congratulations to @AirSpaceIntel on raising $325M at a $3B valuation led by @sparkcapital @Citadel @MeritechCapital! We’re thrilled to have led the pre-seed @GradientVC from the beginning and continue to be blown away by @pbuckendorf and team 🚀
bloomberg.com/news/articles/…
Darian Shirazi retweeted
turns out tissue simulation capability is pretty correlated with frontier intellegence 👀
Congrats @gigsdotcom on being named to @TIME’s Best Inventions of 2026 alongside @Starlink for connectivity! time.com/collection/best-inv…
Darian Shirazi retweeted
Back-to-back robot shipments to New Zealand and India this week — have fun in your new homes, Feather!
Darian Shirazi retweeted
Everyday I learn of a bad leader doing dramatically more damage than I’d think possible.
And a great leader creating dramatically more value than I’d think possible.
Even though I’m already being a big believer in the power of leaders, I still underestimate impact.
Salesforce has $70B of revenue coming up for renewal within the next 3 years
Falling knife imo
Nice coverage of @GamowLabs from the @GradientVC portfolio in the Gemini 4 launch!
"Researchers at Gamow Labs used Argon to analyze de-identified genomes from newborns with rare developmental lung disorders. In one case, Argon pinpointed a chromosomal rearrangement that routine software missed for years, and explained why it went undetected. On private Gamow Labs evals derived from real clinical and lab data, Argon topped on RareBench (57% on assistance with rare-disease diagnosis) and LabBench (52.2% on wet-lab reasoning). These advances point to faster diagnosis for families facing rare conditions."
blog.google/innovation-and-a… @GoogleDeepMind
“If you overbuy, you could bankrupt the company by having too many lease commitments, and if you underbuy, you could knock down your growth trajectory and have a bunch of unhappy users,” said @thezbg, a general partner at @GradientVC
wsj.com/tech/ai/ai-computing…
