Claude has discovered a previously unknown enzyme system hidden in the DNA of bacteriophages. Beside the enzyme’s gene sits a long array of repeating DNA—a structure that looks somewhat similar to CRISPR. We don’t yet understand what this system does, but only a handful of known systems share its features, and all of them are able to cut, copy, and paste DNA. Historically, the discovery of such programmable systems has helped revolutionize medicine. CRISPR, for instance, is now the foundation of genetic medicines. But it will take much more work to learn what this system does, and whether it can be put to similar use. Read more: anthropic.com/news/claude-di…

It’s 31 years since Tony Yeboah unleashed this truly biblical Thunderbastard at Selhurst Park. Sweet Lord Above. What a strike.

The Mayor responds to Zack Polanski in Urdu

📈🎉 Real wages are rising 📈🎉 Pay is growing faster than prices, and faster than last quarter. When workers have more cash, they spend more. And more spending means more growth.

Gloomy forecast for tenants as rent rises set to speed up bbc.in/4ht6Nzd

There's a lot of misinformation flying around about the Tourism levy, so here's the actual facts: It's about investing more money in our communities. Visitors come to our towns and cities every year. This gives local leaders the option to levy a small charge on the cost of their accommodation and reinvest that money into local needs. It's local choice, not a national tax. The government is providing the framework, but it's for mayors and local communities to decide whether a levy is right for their area and what it should look like. Budget trips are protected. Because the levy is linked to the cost of accommodation, lower-cost stays will pay less, meaning cheaper holidays and short breaks remain affordable. This is part of the wider devolution agenda. This is about trusting mayors and local leaders with more powers and more control over decisions that affect their local economy.

🚨 WATCH: Andy Burnham's second round of PMQs, "People's Major Questions"

In a difficult and dangerous world, a decade on from Brexit, there is a risk that Britain loses the confidence to lead and stand up for its values. I’m not prepared to let that happen. It is more important than ever that Britain stands for something. We have called for years for a two-state solution in the Middle East, but we must recognise that those words are meaningless unless we back them up with action. For too long, we have been hesitant to act, fearful of being accused of being anti-Israel. Today we are announcing carefully judged, targeted steps that are not aimed at the Israeli people, but at the unacceptable policies of the current Israeli government. The suffering of the Palestinian people is a scar on the conscience of the world. Innocent Palestinians, including children, continue to be killed in Gaza. And there is still a humanitarian crisis, with far too little aid getting in. The scale of destruction is hard to comprehend. More than 70,000 people lie dead - at least 20,000 of them children. Families and communities have been torn apart. Millions displaced. And the population of Gaza is now penned into just one third of the territory. I know that people across the UK feel very deeply about this issue - and so do I. Before I became Prime Minister, I said our country’s response had been too slow and simply not good enough. That’s why I committed to changing the government’s approach. I will not stand by as the horrific suffering continues to grow and the prospect of a two-state solution - the best hope for peace and stability in the region - comes under attack. More settlements have been approved under the four years of this Israeli government than in the previous 20 years. The UN has reported more than 1,500 incidents of settler violence so far this year, aimed at driving out Palestinians. And the situation is growing worse, fast. The Israeli government has now approved 104 new settlements since it took office in December 2022, and ahead of the October elections in Israel, it is allowing tenders for the construction of the E1 mega settlement to go ahead. This would cut a swathe through the heart of the West Bank - snuffing out the hope of realising a two-state solution. It cannot be allowed to happen. That’s why we are announcing a new package of tough measures to put pressure on the Israeli government: First, we will ban the trade in goods with illegal settlements in Palestine. Second, we have formally changed the view of the British government to say for the first time that the Israeli occupation of Palestinian territory is unlawful - independent of, but in line with, the conclusion of the international court of justice. And third, we will sanction individuals and companies that support, facilitate or profit from illegal settlements. That includes any businesses or investors that take part in the construction of the E1 settlement. In addition, we are announcing a new package of desperately needed humanitarian aid to Gaza. We are taking these steps because it is the right thing to do. I have condemned the monstrous terrorist attack on Israel on 7 October 2023 in the strongest possible terms - and continue to condemn Hamas. However, it does not justify the Israeli government’s actions in Gaza or the West Bank. The measures we are taking are about targeting illegal settlements and increasing the pressure on the Israeli government to change course. We are not imposing sanctions on Israel as a whole, which would punish the Israeli people, many of whom disagree with their government’s position. The Israeli people are not responsible for the actions of their government. And nor is the Jewish community in the UK. Blaming British Jews for the actions of Benjamin Netanyahu’s government is wrong, plain and simple. And it is antisemitism, plain and simple. I met the representatives of the Jewish community just last week. I know the fear they live with day by day. My government will stop at nothing to ensure they are safe and to stamp out antisemitism in every part of our society. The measures we are announcing today are about protecting the only solution that could see the Israeli and Palestinian people living side by side in peace and security - something that people up and down the UK desperately want to see. The government I lead will keep working with our partners around the world to keep that hope alive.

I think education should be about what you can do, and not what you can’t do. Read my full piece in @theobserveruk where I set out my vision for reforming England's education system - from tackling the SEND crisis to reimagining what success looks like beyond exams. observer.co.uk/news/national…

This is public ownership of our railways in action. Less than 100 days since we nationalised Britain's biggest train operator, we are delivering changes passengers have been asking for. thetimes.com/article/985c01c…