Structural Biologist & Research Fellow @ MGH, HMS / TGF-Beta family: Anti-Müllerian Hormone / @SocExpBioMed Councillor & EBM Trainee Editor
Boston, MA
Joined October 2011
- Tweets24
- Following451
- Followers105
- Likes58.9K
Drew Howard retweeted
Don't miss your chance to delve into the forefront of biomedical innovation with SEBM! Secure your spot at our 2025 #EBMC conference today and join us in shaping the future of #biomedical research. 🧬✨ Register to attend this ground breaking conference at loom.ly/CeVDZV0
Baby’s First Paper!
A divergent two-domain structure of the anti-Müllerian hormone prodomain | PNAS pnas.org/doi/10.1073/pnas.24…
Drew Howard retweeted
Last chance to apply to the Cold Spring Harbor #cryoem course this March (application deadline is Jan 15th)! Learn all about sample prep, microscope operation, and image processing at this fun 2-week course @kollmanlab @Jen_Cash_11 @cshlcourses meetings.cshl.edu/courses.as…
Drew Howard retweeted
Our lab presented six poster presentations and gave three oral presentations showcasing our latest work. 😎💪
Above all, we were delighted that Drew Howard won first award for best short talk and Jacob Mast won second prize for best poster presentation. 🏆👏🔝
ALT Tom's talk "Structural diversity of TGF-β signaling"
ALT Drew's short talk "Structural Basis of Non-Latent Signaling by the Anti-Müllerian Hormone Procomplex"
ALT Jacob's poster "Characterization of the Molecular Mechanism of Erythroferrone Antagonism and Specificity"
Drew Howard retweeted
Hey all new(ish) structural biology PIs out there - I started a slack workspace geared toward us! If you’d like to join, DM me your email and method(s) of choice, and I’ll add you to the group.
Drew Howard retweeted
Structural Basis of Non-Latent Signaling by the Anti-Mullerian Hormone Procomplex biorxiv.org/cgi/content/shor… #biorxiv_molbio
Drew Howard retweeted
We are thrilled to share our latest preprint on the Anti-Müllerian Hormone and its unique signaling pathway. Our first ever cryo-EM structure represents a breakthrough over 40 years in the making. 🧬🔍
(@drewhow66)
Check out our findings here:
biorxiv.org/content/10.1101/…
1/10
Drew Howard retweeted
Very cool! I believe this counts as manual blotting, yes?
CryoCycle your grids! Plunge vitrify & reuse clipped cryoEM grids. We show vitrified proteins & cells (thin areas), offering $10k+/yr in savings. Added benefits: simpler clipping, less grid damage, no frozen fingers, & no need for commercial plungers.
biorxiv.org/content/10.1101/…
Drew Howard retweeted
A great course, and lots of fun (at least for me)!
The deadline for the CSHL 2024 Cryo-Electron Microscopy Course is Monday, January 15th! Click the link below to be apply today! Good Luck!
meetings.cshl.edu/courses.as…
Drew Howard retweeted
Two decades ago @AvigdorEldar & @BarkaiLab introduced concept of shuttling, in which protein circuits push morphogens away from their source, or smush them into narrower regions. We have now reconstituted shuttling in mammalian cell culture: science.org/doi/10.1126/scia….
Join me in supporting Emma Curtis via @actblue secure.actblue.com/donate/em…
Drew Howard retweeted
In his 1952 classic, Turing showed that ≥2 interacting, continuously diffusing morphogens can spontaneously generate beautiful biological patterns. On a discrete cell lattice, we find that 1 morphogen is enough for stable spatially periodic patterns cell.com/cell-systems/retrie…
Drew Howard retweeted
New Research: Molecular Mechanisms of AMH Signaling: Anti-Müllerian Hormone (AMH) is a secreted glycoprotein hormone with critical roles in reproductive development and regulation. Its chemical and mechanistic similarities to members… frontiersin.org/articles/10.… #Endocrinology #Endo
Drew Howard retweeted
Check out the latest mini review from our lab discussing the exciting biochemical advances in understanding the signaling mechanism of AMH and its receptor, AMHR2. Special congratulations to Drew Howard, one of our 2nd year graduate students! frontiersin.org/articles/10.…
Drew Howard retweeted
Check out our new 3D protein display featuring structures solved by @SeegarLab, @KovallRhett Lab, and us @ThompsonLab3!! Thank you to the @UC_CEAS digital fabrication lab for making this collaboration possible.
Drew Howard retweeted
Excited to share the work of @Kaitlin_Hart12, a graduate student in our lab, who worked to solve the novel binary structure of Anti-Müllerian hormone (AMH) bound to type II Ser/Thr kinase receptor, AMHR2. pnas.org/content/118/26/e210….