@ecuppen

Edwin Cuppen is scientific director of the Hartwig Medical Foundation a nonprofit organisation that aims to improve cancer care by whole genome sequencing

 Bilthoven
Joined March 2011
  • Tweets711
  • Following136
  • Followers831
14Media
#SBX vs. @Illumina: Genome-Wide Coverage SBX provides higher coverage in high-GC regions, earlier drop-off in low-GC. With MAPQ>20, SBX covers 95.6% (1X) vs. 97.3% (Illumina). In GIAB high-confidence, SBX achieves 99.82% (1X), 99.45% (10X). #AGBT25 #AGBT2025 #AGBT @AGBT @Roche
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SBX vs. Illumina: SNV & INDEL Concordance In 30 patient samples, SBX shares 97.4% SNVs with Illumina, detects 2,449 unique SNVs (0.9%) vs. 4,470 Illumina-only (1.7%). INDELs are mainly T homopolymers, with SBX enriched in 464 sites vs. 1,088 for Illumina. #AGBT25 #AGBT2025 #AGBT @AGBT @Roche
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Less than a week for registration. Check out the program: ccg2025.eu. With keynotes by @nlbigas and @CharlesSwanton and exciting sessions on clinical implementation and impact, research insights and future developments around cancer whole genome sequencing #ccg2025
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Start the new year well and register in time for the Clinical Cancer Genomics meeting 2025. Don't miss out on the great line-up of speakers covering the impact of whole genome sequencing in clinical practice, the value for research and a glimpse into future developments.
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Clinical Cancer Genomics 2025: two more weeks till registration deadline! Check out the website for detailed program and speakers. The meeting includes a session with presentations from all major cancer whole genome sequencing initiatives in Europe. ccg2025.eu
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Hear the latest about their achievements, clinical impact and plans for the future! The session will be concluded with a forward looking discussion with the speakers: @StefanFrohling , Frédérique Nowak, Matthew Brown, Bettina Lundgren, Richard Rosenquist Brandell, @ecuppen.
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I have left x for bluesky: bsky.app/profile/ecuppen.bsk…
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Our collaboration with @HartwigMedical will utilize the UG 100 sequencer & ppmSeq to offer high accuracy sequencing at reduced costs - expanding whole genome-based cancer diagnostics accessibility and improving treatment outcomes. Read the full PR here: businesswire.com/news/home/2…

Hartwig and Ultima Genomics Collaborate to Reduce Costs for Whole Genome Cancer Profiling, Minimal...

Hartwig Medical Foundation, a pioneer in deploying complete genomic profiling to improve oncology outcomes, and Ultima Genomics, a developer of a revolutiona...

businesswire.com
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Given that there are more treated than untreated cancer patients, papers such as this one deserve more attention (and citations). Re-posting mutational footprints of cancer therapies. nature.com/articles/s41586-0…
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📅Op dinsdag 7 november organiseert het Antoni van Leeuwenhoek in samenwerking met @prinsesmaximac en @HartwigMedical een symposium over de laatste ontwikkelingen in Whole Genome Sequencing. Bekijk het programma en schrijf je in ➡️ bit.ly/3LGbAy8
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📅Op 28-11-2023 is het Patient Impact Award DRUP Symposium in het AVL. Er zal worden uitgelegd waarom DRUP de Patiënt Impact Award 2022 heeft gekregen en hoe DRUP een bijdrage levert aan het verbeteren van de zorg voor patiënten met kanker. Lees meer ⬇️ bit.ly/4687cQ0
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⚠️Are u passionate about advancing our understanding of cancer biology 🧬and are eager to be part of a dedicated team at the forefront of translational research🏥? We have an open position for a bioinformatics research assistant 💻! Please RT! vhio.net/2023/08/30/ref-63-2… @VHIO

Ref. 63-2023 Bioinformatics Research Assistant (Cancer Immunogenomics) (Process closed) - VHIO

The Vall d´Hebron Institute of Oncology (VHIO) Seeks a “Bioinformatics Research Assistant”   Reference: Ref. 63-2023 Application deadline: 19 September...

vhio.net
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finally 🙏 to the patients who gave samples, to TCGA, ICGC, PCAWG, Hartwig medical for creating the ✨ resources that 🚀ed this work, & all the 🤩 trailblazers in the HRD signature field @SerenaNikZainal @ecuppen @PolakPaz @getz_lab who set the stage for this work! 🙌 18/18
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In the field of personalized medicine and whole genome sequencing (WGS), keeping continuously up to date with the latest knowledge about treatment options is essential. ictandhealth.com/collaborati… @HartwigMedical #icthealth

Collaboration between Hartwig and CKB makes both parties stronger | ICT&health

Hartwig Medical Foundation has worked with The Jackson Laboratory (JAX) Clinical Knowledgebase (CKB) team since 2020, to the benefit of both parties. For each individual patient’s tumor, Hartwig...

icthealth.org
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Thank you for a great first Workshop day on Trusted Clouds for Genomics Research in Europe! @ecuppen (@HartwigMedical) and @PatrickKemmeren (Princess Máxima Center) talked about enabling research, while @sj_capella (@BSC_CNS) highlighted a path to a TRE! 1/2
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Waarom Den Haag zo tergend traag beleid maakt (afstemmen, afstemmen, afstemmen) decorrespondent.nl/14622/waa… via @decorrespondent
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Today at #EARC2023 @fran_mj88 : Pan-cancer whole genome comparison of primary and metastatic solid tumors.
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If you are at the #EACR2023 meeting I'll be presenting this work in the afternoon session!
Edwin Cuppen@ecuppen12 Jun 2023
Very proud to see our work on the pan-cancer comparison of the genomic landscapes of primary and metastatic tumor published in this weeks issue of Nature: nature.com/articles/s41586-0…. @fran_mj88 @arne_van_hoeck @HartwigMedical @UMCU_CMM @oncodeinstitute @VHIO
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Very proud to see our work on the pan-cancer comparison of the genomic landscapes of primary and metastatic tumor published in this weeks issue of Nature: nature.com/articles/s41586-0…. @fran_mj88 @arne_van_hoeck @HartwigMedical @UMCU_CMM @oncodeinstitute @VHIO
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For the benefit of cancer patients, who unfortunately still have very large unmet needs, all stakeholders, from medical specialists to hospital directors, to policy makers, legislators and care insurers, should team up to facilitate AND realize self-learning care systems.
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We call upon all relevant parties in The Netherlands to capitalise on their unique position and use this mostly Dutch resource as a powerful basis for building #bigdata solutions for sustainable cancer care. @Health__RI @constantijn14 @MinVWS @ZNnieuws @ZiNLActueel
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