Health economist @JohnsHopkinsSPH @JHSPH_HPM

Baltimore, MD
Joined January 2011
Joe Levy retweeted
Nearly one-third of first-time #prescription attempts for single-source branded drugs in the US were rejected due to formulary exclusion or utilization management, with more than 48% resulting in no dispensed therapy in the same class within 90 days. ja.ma/4vnWIZg
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We have a new paper in @JAMA_current documenting the now-ubiquitous nature of formulary management for brand drugs By 2024, 40% (!) of initial attempts to fill a brand drug were rejected for prior auth or formulary exclusion (most of the growth over time is more prior auth)
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Under the IRA, Part D plans have responded to lower out-of-pocket limits with higher deductibles The result is a sharp "tilting" of OOP spending through the year. Average OOP costs for brand fills are now higher in January, but sharply lower in later months as people hit the cap
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AHRQ-funded researchers calculated the US could save $150M every year by switching from low molecular weight heparin to aspirin for blood clot prevention in orthopedic trauma patients. (That grant cost <$100K.) pubmed.ncbi.nlm.nih.gov/4066…
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Very interesting to get a deeper look at what Medicare coverage of the weight loss drugs might cost, taking into account existing rebates & considering the counterfactual that many are likely to gain coverage through other indications over time regardless.
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And go.....
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FDA approval of 2nd potent GLP-1 for treatment of obesity - Lilly’s drug Zepbound - will accelerate discounting as competition heats up, reducing costs and extending access to patients. A prior @AEIecon analysis captured magnitude of earlier discounts aei.org/wp-content/uploads/2…
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Ozempic, Wegovy, and other GLP-1s perfectly illustrate the common (and large) gaps between list and net prices of many brand drugs. A summary of our work: "Ozempic and Wegovy Don’t Cost What You Think They Do" via @nytimes nytimes.com/2023/10/22/healt…
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Hmm: New @AEI study estimates huge #GrossToNetBubble for GLP-1 #drugs. Net prices far below list prices due to #PBM #rebates & manuf copay support 👇 Perhaps economic impact has been overestimated? Full report: drugch.nl/3tiWRCB
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Now in print, @jlevy2 and I test whether coverage of brand drugs in Part D differs based on whether the drug is a "good" or "bad" value relative to cost-effectiveness estimates. In short, it does not. aei.org/research-products/wo…
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Defining “the price” of brand drugs like Ozempic can be complex. Our white paper summarizes what we know about the prices of new treatments for diabetes and obesity Short story: Very big differences between list and net prices, even adjusting for coupons aei.org/research-products/re…
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CMS will use comparative effectiveness to adjust the starting point in price negotiations, but how exactly? We adapted the French system (added benefit ratings linked to domestic reference prices) to model one approach and estimate savings. @jlevy2 valueinhealthjournal.com/art…
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My new @NEJM Perspective with @SeanTunis: @CMSGov is becoming a major #HTA organization. It should embrace the role. tinyurl.com/3f56499a @TuftsCEVR @TuftsMedicalCtr @Arnold_Ventures @HTAiOrg @UW_Pharmacy @SchaefferCenter @DusetzinaS #heor @a_kaltenboeck @joeymattingly
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Great morning discussing health care price transparency and patients out of pocket costs at #IHEA2023 @KellyAnders0n @Angela_HSR @Mark_Meiselbach @michalhorny @AssumeNormality @ashleyleech – at Cape Town, South Africa
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Hey #ARM23 attendees, looking for one last session to close out an amazing few days? Check out this late-breaking session: “Medicare and Drug Pricing and Spending” today at 10:30am. Come learn about findings from the Transparency in Coverage insurance disclosed pricing data!
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