Doha, Qatar
Joined April 2009
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Khaled Machaca retweeted
WCM-Q hosts international calcium signaling meeting @WCMQresearch
qatar-weill.cornell.edu/medi…
Postdoctoral position available in the Lab focusing on the cellular regulation of calcium signaling pathways during cell division and differention. If interested please apply at the below link. wcmq-academicpositions.odoo.…
If you’re interested in organelle contact sites, check out our latest review discussing their regulation during cell division. Quite interesting how cells differentially modulate different junctions. journals.sagepub.com/doi/10.…
Rapid Progesterone signaling remains poorly defined. Here we show that progesterone signaling during meiosis requires two receptors mPRb and ABHD2 working in tandem to induce lipid signaling through PLA2. An important contribution to mPR signaling. elifesciences.org/articles/9…
Check out our recent paper validating the physiological role of calcium tunneling in secretion and sweating rupress.org/jcb/article/224/…
Khaled Machaca retweeted
Mapping the detailed architecture of Ca2⁺ tunneling and modulating its function using a novel tunneling inhibitor show that tunneling enhances Cl⁻ secretion in cells and sweating in vivo. New from Courjaret, @kmachaca et al. @WCMQatar: hubs.la/Q02X6vQv0
#Physiology
Heartfelt congratulations to the five laureates for the #FWIS 2024 life science edition. An impressive group of scientists with exceptional achievements and impact. bit.ly/3JZbHn2
Great pleasure to be attending the L’Oreal UNESCO FWIS award ceremony at the UNESCO headquarters. #fwis2024 #4womeninscience
Great opportunity for a young assistant professor in a vibrant research environment at WCMQ and in Qatar to perform cutting edge cell biology research with translational potential. wcmq-academicpositions.odoo.…
Khaled Machaca retweeted
The official launching of the Qatar Precision Health Institute (QPHI). Qatar Biobank & Qatar Genome join forces, under one umbrella, ushering a new phase of Qatar Foundation’s mission to help put Qatar at the forefront of Precision Health implementation. @QF @QatarGenome @_QPHI
HH Sheikha Moza bint Nasser Inaugurates Qatar Precision Health Institute. #QNA
#Qatar
ow.ly/SVq450RsXOl
Check out this large collaborative effort re computational approach to drug design nature.com/articles/s41598-0…
Khaled Machaca retweeted
Inflammation is a common feature of many diseases.
Murali Prakriya, PhD, discusses the evolution of this groundbreaking research in ion channels and his latest findings, which were published in @NatureComms, in this episode of our #BreakthroughsPodcast.
spr.ly/6018kJdyC
Contact sites between organelles are critical for cell physiology. Interestingly during cell division the contacts between the ER and mitochondria expand with implications on cellular energetics. cell.com/iscience/fulltext/S…
Khaled Machaca retweeted
“Having read (doi.org/10.1093/function/zqa…) and associated papers, I urge the @APSPhysiology community to join me in requesting a transparent investigation of @APS_Function editorial practices and standards. #AcademicIntegrity #OpenScience”
Our (@TrebakM Hogan) rebuttal is out in @APS_Function. Scientific discourse is always welcomed! Does the editorial by @APS_Function editor qualify? You judge
@APSPhysiology
Reappraisal of The Reappraisal - CRAC Channels Are Activated by L-Type Ca2+ academic.oup.com/function/ar…
Khaled Machaca retweeted
Congrats to all on a fabulous collaboration between the Yule and Patel labs exploring cross-talk in calcium signaling between lysosomes and endoplasmic reticulum.
cell.com/cell-reports/pdf/S2…
Khaled Machaca retweeted
Had great discussion at @BioTechX_ ! #GenerativeAI in medicine holds the potential to revolutionize drug discovery, medical imaging & personalized treatment by generating novel compounds, improving diagnostic accuracy & tailoring therapies to individual patients #AI @WCMQresearch
Khaled Machaca retweeted
Our new study by PhD student Cory Benson published in JBC on Ca2+ oscillations in T cells. CRAC, IP3R and IP3, all oscillate. Thanks @DavidYule64 @NadineHempel, James Sneyd and all authors
jbc.org/article/S0021-9258(2…
