David Yule retweeted
TPC2-mediated lysosomal Ca2 release puts the brakes on store-operated… sciencedirect.com/science/ar…
David Yule retweeted
Discovery of new AMPA receptor regulators – RNA molecules that act as competitive antagonists causing CNS-related toxicity when intended for treatment of autosomal dominant polycystic kidney disease (ADPKD). Collaboration with Regulus Therapeutic/Novartis! nature.com/articles/s41467-0…
David Yule retweeted
Delighted to receive copies of the (just published) book on statistics that @JakubTomek13 and I have written. Presents statistics and related experimental design without maths and jargon. Available from: amazon.com/Basic-Statistics-… or wiley.com/en-us/Basic+Statis…
David Yule retweeted
Happy to share the locking mechanism of human oncochannel TRPV6 inhibition by intracellular magnesium. Amazing collaboration with Chubanov and Efremov groups. nature.com/articles/s41467-0…
Please read my reply physoc.onlinelibrary.wiley.c… to Ole Petersen’s letter physoc.onlinelibrary.wiley.c… to the Journal of Physiology regarding our paper physoc.onlinelibrary.wiley.c…
Open discussion is good for science.
David Yule retweeted
Our Lab(@jyotitanwar1993, @Kriti_ahuja9090 & others) just returned from an exciting Lab retreat from Ranthambore National Park & Garadia Mahadev, Rajasthan! Our sincere gratitude to @EMBO Global Investigator Fellowship for funding support! Many thanks to @unescorcb @DBTIndia!
David Yule retweeted
Structures of kainate receptor channel GluK2 in the apo closed and open conducting states, both with 2-fold symmetrical LBD layer. To open the channel, we used agonist kainate and positive allosteric modulator BPAM but no Concanavalin A! @shantigangwar
nature.com/articles/s41594-0…
David Yule retweeted
Excited for our study in NAR, "ACE-tRNAs are a platform technology for suppressing nonsense mutations that cause cystic fibrosis". The first of a couple of collaborative studies that demonstrate the potential of ACE-tRNAs as a platform therapeutic. academic.oup.com/nar/article…
David Yule retweeted
Excited to pre-release the latest from the lab on how arterial myocyte Panx1 controls vascular reactivity in diabetes. Massive effort from the M&M Team in collaboration with @conn_pann_fun and Xiang Lab.
@ucdavis, @UCDAVISPharmac1, @UCDavisHealth.
ahajournals.org/doi/10.1161/…
David Yule retweeted
Loss of the calcium sensor #STIM2, but not of STIM1, worsens #ColorectalCancer growth and metastasis by boosting calcium ion content in the endoplasmic reticulum, remodeling mitochondria, and rewiring transcriptional activity. @TrebakM @Trayambak_P scim.ag/44v3O3E
Check out our new paper. A great collaboration between the Yule, Orlandi and Groblewski labs:physoc.onlinelibrary.wiley.c…
David Yule retweeted
Planning for European Calcium Society Main Meeting (ECS2026) by Khaled Machaca & team in Doha, Qatar is in full swing with most speakers confirmed.
Meeting website for updates: qatar-weill.cornell.edu/even…
The meeting will be held at Sheraton Doha from Feb 1-4, 2026. @EuroCalcium
New paper from the lab in press in JBC. Please check it out.
jbc.org/article/S0021-9258(2…
David Yule retweeted
Postdoctoral position available in the Lab focusing on the cellular regulation of calcium signaling pathways during cell division and differention. If interested please apply at the below link. wcmq-academicpositions.odoo.…
David Yule retweeted
Last week @adamsgreenstein and I had the honour and surprise of winning the @TheBHF Research Story of the Year award. The award was based off our work published last year in PNAS, and was only possible due to an amazing group of scientist at @OfficialUoM and @GJBrainResearch
David Yule retweeted
Check out our study published in NAR. #nonsense #tRNA
Optimization of ACE-tRNAs function in translation for suppression of nonsense mutations academic.oup.com/nar/article…
David Yule retweeted
Animated summary of our study published in @PLOSBiology journal by a highly talented and motivated PhD scholar @Kriti_ahuja9090!
Paper's link: journals.plos.org/plosbiolog…
@NatureInd @IndiaBioscience @SciComm_India @unescorcb @DBTIndia @India_Alliance
Latest work from lab- Mito Ca2+ uptake affects skin pigmentation!
While it's fun to carry out exciting experiments, I also enjoyed animating the gist of our study.
Mentor: @MotianiRaj1
Funding: @India_Alliance
@unescorcb
@jyotitanwar1993
Full Article-journals.plos.org/plosbiolog…
