Research Officer at the Queensland Spatial Biology Centre (@Qld_SBC), Wesley Research Institute, Australia. Views are my own. She/Her.

Brisbane, Australia
Joined August 2014
1/ After a huge team effort, we’re thrilled to share our latest study exploring the tumour microenvironment in NSCLC 🎯We integrated spatial proteomics, transcriptomics, and machine learning to uncover how the architecture and metabolism of the TME relate to patient outcomes.🧵👇
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🚨New paper alert! 📷 We are excited to announce the publication of our latest paper, “Proximity and metabolic activity of the Tumour Microenvironment as predictors of survival in High Grade Serous Ovarian Cancer”, is now live📷doi.org/10.1016/j.isci.2025.…
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Meg Donovan retweeted
Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer @NatureGenet @OncoAlert #SpatialMedicine #lungcancer #PrecisionMedicine nature.com/articles/s41588-0…
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A collaboration between TRI-based scientists from @UQ_News and @Yale is using a Google maps approach to revolutionise lung cancer treatment. bit.ly/4o9qFJ2 bit.ly/4q1NmAJ @aruthak @SpringerNature @WEHI_research @CureCancerAu @PARFoundation @WesleyResearch @NIH
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Meg Donovan retweeted
PRISM: a Python package for interactive and integrated analysis of multiplexed tissue microarrays academic.oup.com/nargab/arti…
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Did you catch the @Qld_SBC on @Channel9? @aruthak shared an exciting world-first discovery! His team has profiled hundreds of proteins & thousands of gene messages from just a single tissue slide, using samples from 84 patients with head & neck cancer. bit.ly/4lyceNx
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Cellular keys to cancer survival/treatment resistance have been unlocked. Scientists including TRI-based @aruthak mapped the tissue microenvironment to identify immune cells linked to living longer with disease in remission. The work is in The @australian. bit.ly/4lBuohx
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In a world-first discovery from the @Qld_SBC , doctors can now check hundreds of markers in a single biopsy to show which treatments, like #immunotherapy, #chemotherapy or #radiotherapy, will work best for patients with head and neck #cancer. Learn more wri.org.au/QSBC
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Meg Donovan retweeted
Assoc. Prof Arutha Kulasinghe (Director of Science QSBC) and the Wesley Research Inst. dedicated team, trying to make living with Cancer a much more manageable outcome for all. It's a privilege to work along side them as the Consumer Advocate rep. Well done to the team
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🚨Excited to share our latest paper from the #ClinicaloMxLab #QSBC where we spatially resolved >580 proteins in head and neck cancer! This is the largest spatial proteomic panel currently commercially available for fresh frozen and FFPE samples 💪 nature.com/articles/s41698-0… [1/12]
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Replying to @aruthak
@aruthak sat down with the @AACR to talk all things spatial biology. His team at @Qld_SBC are using cutting-edge spatial biology approaches to gain deeper insights into patient biopsies and surgical resections across a range of tumour types. Read 👉 wri.org.au/3SCK07X
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Members of WRI had the pleasure of attending the Art of Medicine exhibition at @gabbaart. An inspiring initiative exploring the intersection of science, art, and wellbeing in medicine. We were proud to showcase three high-resolution #spatialbiology images from @Qld_SBC
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Replying to @Qld_SBC
@Qld_SBC team have presented cutting-edge #cancerresearch findings at the world’s largest #cancer #research conference in Chicago this past week, highlighting how immune cells can block the body’s response to #immunotherapy in aggressive head & neck cancers. @aruthak @megldono
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Did you see @Qld_SBC in the news yesterday? 📰 🔬 The story highlights an innovative study by researchers at WRI, who have uncovered a crucial factor that determines whether patients with head and neck cancer will respond to immunotherapy. Learn more - wri.org.au/42Rgu35
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