Group leader of the Nanoscale Bacteriology Lab at the Rudolf Virchow Center @Uni_WUE. Revealing the inner life of #bacteria using #SuperResolutionMicroscopy.
Würzburg, Germany
Joined March 2020
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Happy to share our preprint on DeepBacs, a project dedicated to all bacteriologists working with #microscopy. In #DeepBacs, we employ open-source #DeepLearning tools for various tasks in bacterial bioimage analysis. A thread will follow soon! 🦠🔬🧠
biorxiv.org/content/10.1101/…
Christoph Spahn retweeted
🚨🔬💗Whether investigating cell organelles or mapping proteins, together with @PuellesVictor's lab we lay a roadmap for selecting optimal #ExM and #SuperResolution #microscopy combinations. @ArisDaria and Dominik Kylies review with amazing co-authors
pubs.aip.org/aip/apr/article…
Christoph Spahn retweeted
Researchers have created hybrids of biological motor protein and nonmotor #DNA binding domains that walk unidirectionally on synthetic DNA tracks containing the recognition sites for the DNA binding domains.
Learn more on #DNAday: scim.ag/4lJFSQM
Christoph Spahn retweeted
Single-molecule localisation microscopy & live-cell imaging reveal fine details of chromosomal organisation underlying growth of E.coli
📷 @miCHRIScopy et al @Uni_WUE in @NatureComms
➡️ bpod.org.uk/archive/2025/4/2…
Our nucloid organization work is finally out @NatureComms:
doi.org/10.1038/s41467-025-5…
and rdcu.be/eiqzl
We visualized the E. coli nucleoid during drug treatment, suggesting that transertion mediates nucleoid anchoring to the membrane. #superresolution #microbiology
Thanks to all coworkers and people sharing material!
@HeilemannLab
@seamus_holden
@HenriquesLab
@HelgeBode_Lab
@stumiddlemiss
@gomez_mariscal
@carpousis
Christoph Spahn retweeted
🎊Fantastic work!!! This pre-print by @LE_Laurent_ @S_LevequeFort et. al introduces Brightness Demixing for simultaneous 3-target imaging using 1 laser🤯
📷 Our #DNAPAINT ready 2ry antibodies & imagers were used for vimentin, clathrin,& tubulin imaging
biorxiv.org/content/10.1101/…
Christoph Spahn retweeted
Synthetic Carbon fixation just got a boost 🚀: Synthetic Biology outperformed Nature in a Living Bacterium. Check out the new work from @BDronsella @erblabs together with @NicoC_MicSynBio @MIB_WUR #synbio, #formatebioeconomy
mpi-marburg.mpg.de/1493129/2…
Christoph Spahn retweeted
🚨 Fully funded summer research opportunity! 🚨
Yorkshire uni students: Spend 9 weeks in my lab using high-resolution microscopy to visualise Streptococcus pneumoniae! 🦠🔬
📅 Apply by March 8th
🔗generationresearch.ac.uk/stu…
#Internship #Microscopy #Microbiology #STEM #AFM
Christoph Spahn retweeted
ÅNGSTRÖM-RESOLUTION IMAGING OF CELL-SURFACE GLYCANS 🧬🎨🍬
The glycocalyx, our cells' sugar coat, holds secrets in immunology, cancer, viral infections, and more. Visualizing its molecular architecture was impossible… until now. #glycotime #microscopy
biorxiv.org/content/10.1101/…
Christoph Spahn retweeted
🚨🚨 MEGA JOB ALERT 🚨🚨
Independent Group Leader Positions in Computational Biology @humantechnopole!
Are you ready to start your own lab? Do you know someone who is? Repost this + share with everyone who might want to know about it. Thanks!!! 🙏
More details below... 🧵 1/3
Christoph Spahn retweeted
What a pleasure to see our bacterial-MERFISH work out in @ScienceMagazine this week! Congratulations to the talented team that led this effort--Ari, Yuanyou, and Nana! science.org/doi/abs/10.1126/….
Christoph Spahn retweeted
Exciting Opportunity! 📣 The Max Planck Institute for Terrestrial Microbiology is hiring a Head of the DNA Biofoundry. Join us in vibrant #Marburg to develop cutting-edge automation platforms that empower synthetic biology research. 🗓️ Apply by Feb 15, 2025. #ScienceJobs #SynBio
Christoph Spahn retweeted
Hey PIs, do your trainees need to learn light microscopy and image analysis? Send them to us! Financial aid is available.
meetings.cshl.edu/coursesint…
Christoph Spahn retweeted
Our first baby @itqbnova. First of many to come =)
🚨🔬🤖📜 Paper is out! Introducing the #LiquidEngine and #NanoPyx - novel #AI strategies for accelerating #microscopy that explore how to maximise performance 🚀. Brainchild of @Bruno_MSaraiva, @inesmcunha and @Antonio_DBrito. Faster #SRRF and #eSRRF!!
📰: nature.com/articles/s41592-0…
Christoph Spahn retweeted
We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @institutpasteur All details on our web site : research.pasteur.fr/en/call/…
Congratulations Christophe Zimmer @NanoscAI, Ivo Boneca @ivo_boneca and Mark Brönstrup on the ERC Synergy Grant! 🎉🍾🌟
Great news for #AMR research 🦠💻💊
Congratulations @ivo_boneca @institutpasteur / Mark Brönstrup @Helmholtz_HZI / Christophe Zimmer @Uni_WUE on the @ERC_Research Synergy Grant: a new AI-based approach to make the systematic search for new #antibiotics more efficient! #ERCSyG #AI4AMR
uni-wuerzburg.de/en/news-and…
ALT Professors Christophe Zimmer, Ivo Boneca and Mark Brönstrup (from left) receive an ERC Synergy Grant. (Photos: Felix Knote, University of Würzburg / János Krüger, HZI)
Christoph Spahn retweeted
It is out! #NanoPlex is the universal strategy for multiplexing any immunofluorescence using erasable #nanobodies from @_NanoTag_. We showcase easy multiplexed STED, STORM, and 21-plex Confocal #Microscopy. Published in @NatureComms here: rdcu.be/dWvzO
🤩 looks like a fantastic tool to identify and quantify repetitive structure in your SMLM data! Cool work by @afonsomendes92 @HenriquesLab and co-workers! 🔥
🚨🖥️🦠 OMG! #SReD is live and SHREDDING! Tap into the power of structural repetition to see new things! I'm clearly biased, but our method sure isn't! Let me show you what it can do 🧵👇doi.org/10.1101/2024.09.16.6… #opensource #microscopy #biology
Christoph Spahn retweeted
🚨🖥️🦠 OMG! #SReD is live and SHREDDING! Tap into the power of structural repetition to see new things! I'm clearly biased, but our method sure isn't! Let me show you what it can do 🧵👇doi.org/10.1101/2024.09.16.6… #opensource #microscopy #biology