A research group interested in proteomics, peptidomics, and PTMomics in neuro-diseases📍@TU_Muenchen | CLINSPECT-M consortium | opinions are my own (Chien-Yun)
Germany
Joined September 2018
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Kicking off the new year strong! 🚀
Prosit-Cit is officially online on MCP! Check it out: mcponline.org/article/S1535-…
Follow us on Bluesky for more exciting research updates! @ msleelab.bsky.social
New preprint from us is out! 🍻
We developed a deep learning model to predict MS2 spectra of citrullinated peptides, improving site ID by up to 14x in human tissue proteomes with high precision!
Read more: biorxiv.org/content/10.1101/…
#DeepLearning #Citrullination #Bioinformatics
MS Lee Lab retweeted
💥A week full of top notch science & a lot of fun with scientist from all over the world has come to an end at #HUPOEuPA2024. Many thanks to @hupo_org @EuPAProteomics @EU_YPIC & #DGMS🧵 (1/4)
Come and visit us!
#HUPO2024 starts tomorrow and the Terrific TUM Team is ready! Kusterlab, Wilhelmlab (@wilhelm_compms), Leelab (@msleemslab) and BayBioMS (@BayBioMS) have printed their posters and prepared their talks, and we're very excited for the next days. See you in Dresden!
New preprint from us is out! 🍻
We developed a deep learning model to predict MS2 spectra of citrullinated peptides, improving site ID by up to 14x in human tissue proteomes with high precision!
Read more: biorxiv.org/content/10.1101/…
#DeepLearning #Citrullination #Bioinformatics
This is a project collaborating with Mathias @wilhelm_compms and Wassim @wassimbahaa, and the pipeline is now available through Oktoberfest! 🍻
Can't wait to try it?
GitHub: github.com/wilhelm-lab/oktob…
MS Lee Lab retweeted
Thrilled with #Embocitrullnation success @MAChristoLab thank you all the participants 🤗
Grand merci @IpbsToulouse @IsabelleSaves1 @ToulouseCancer
@GillesFavrecrct
That's already the end of this great @EMBOevents #EMBOcitrullination
Last session to award prizes of the best short talk and poster presentations, granted by the Fondation @ToulouseCancer in the presence of its director Prof. Gilles Favre
Wonderful #EMBOcitrullination workshop with #citrullination experts in Toulouse! We enjoyed all the stimulating discussions! Thrilled by the community's recognition of our research! 🤩Thanks @psharmalab @MAChristoLab @IpbsToulouse and amazing people who make it happen! 👏
MS Lee Lab retweeted
Final Day of #ASMS2024 in Anaheim, but the Terrific TUM Team is far from done! Ludwig from Wilhelmlab will tell you all about Koina today. And at their posters, meet Flo (Kusterlab), Joel (Wilhelmlab), and Miri (@BayBioMS). See you there! One final time: Go #TeamMassSpec!
MS Lee Lab retweeted
It's Wednesday at #ASMS2024 and we are going #kusterscale!
In the morning, you can check out the talks of Nicola and Rebecca (from @msleemslab), in the afternoon Yun and Cecilia will show you their latest results.
All day, you can visit the posters of Johanna and Armin.
See you!
If you’re interested in endogenous peptides and proteolysis in the plasma, come and talk to Andreas! #peptidome #proteolysis #ASMS2024
Here's to another day of exciting posters and talks at #ASMS2024!
Kusterlab and @msleemslab are looking forward to meeting you!
MS Lee Lab retweeted
Here's to another day of exciting posters and talks at #ASMS2024!
Kusterlab and @msleemslab are looking forward to meeting you!
Excited to announce that our team will be at #ASMS2024 with 1 talk and 1 poster! We're eager to connect with fellow #citrullination and clinical #peptidome enthusiasts. See you there! 🎉
Together with Kusterlab @kusterlab and Wilhelmlab @wilhelm_compms we are happy to join #ASMS2024 and looking forward to many awesome discussions! 🤩#TeamMassSpec #TerrificTUMTeam
What's up Anaheim! The Terrific TUM Team, aka Kusterlab, Wilhelmlab, and Leelab, is excited for #ASMS2024. Here is our program for the next few days. We hope to meet many of you there and are excited to check out all of your presentations!
Let's go #TeamMassSpec
MS Lee Lab retweeted
...dose-resolved proteomics (acetylome, phosphoproteome, and full proteome), revealing key insights into drug MoA and enzyme substrate relationships. Explore our dataset on ProteomicsDB 🖥️ Read the full paper here 📖: cell.com/cell-reports/fullte…
MS Lee Lab retweeted
Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics go.nature.com/4a9lMs8
Happy to be part of #DGMS 2024! This afternoon we will be presenting at P104 about our peptidomic workflow revealing thousands of endogenous peptides from plasma samples!
Welcome to Freising!
The Terrific TUM Team is proud to be one of the hosts of this year's DGMS conference.🤩
We are looking forward to four days of presentations, discussions, and networking.
Of course, our labs also have a lot to offer. Check out our schedule below!😎
#DGMS2024
MS Lee Lab retweeted
Humbled to share #upcoming @EMBO workshop on emerging era on #citrullination , July 8–11, 2024 #Toulouse
Grateful for amazing colleagues & co-organizers @IsabelleSaves1 & Françoise Viala @IpbsToulouse
@MAChristoLab M.Simon @InfinityTLS
Website COMING
Please RT #EMBOCit2024
📢Upcoming: EMBO Workshop on protein #citrullination 📢
July 8-11, 2024
Toulouse, France
We will have talks from all facets of citrullination research, several slots for presentations from abstracts and fantastic social events.
#EMBOCit2024 🚀🚀
MS Lee Lab retweeted
📢Upcoming: EMBO Workshop on protein #citrullination 📢
July 8-11, 2024
Toulouse, France
We will have talks from all facets of citrullination research, several slots for presentations from abstracts and fantastic social events.
#EMBOCit2024 🚀🚀
Exciting news! Unwrapping our sarcoma study in @MolSystBiol before the holiday season! 🎄🎁
Kuster-scale? Absolutely!
-2500+ dose-dependent phenotypic responses
-9.7 million sensitivities and protein/p-sites abundance associations
Integration of the phenotypic response of 17 sarcoma cell lines to 139 kinase inhibitors with baseline (phospho)proteomes reveals oncogenic activity landscapes & #drugresponse markers ➡️ embopress.org/doi/full/10.10… @kusterlab @TU_Muenchen #proteomics #phosphoproteomics
Worried about how to use it? Beyond the examples in our paper, a wealth of information awaits your exploration on ProteomicsDB: proteomicsdb.org/sarquarium
Last but not least, huge thanks to all the coauthors and a special shoutout to @kusterlab the terrific support! #sarcoma