Onconius retweeted
🧐
New data from EV302 Enfortumab Vedotin & pembrolizumab for upper tract disease (~25% of pts). UTUC has distinct biological features including more FGFR alterations. PFS & OS HR of 0.50 & 0.53 respectively in the subset is in line with the whole population (0.45 and 0.47) #EAU24
Onconius retweeted
Systematic review of TKI efficacy in NSCLC harboring uncommon EGFR mutations @JTOonline:
- 1836pts, 38 studies
- G719X, S768I, E709X, L747X; compound mtns; & PACC mtns: best ORR to 2nd-gen TKIs
- L861Q best ORR to 3rd gen TKI
@Alfdoc2 @OncoAlert #LCSM
jto.org/article/S1556-0864%2… – at Alexandria, VA
Onconius retweeted
Inhibidores de PARP (iPARP): nuevos fármacos en el cáncer de próstata resistente a la castración metastásico (CPRCm)
onconius.com/blog-1/inhibido…
Onconius retweeted
#Amivantamab y #lazertinib: resultados de los estudios PAPILLON y MARIPOSA
#lungcancer #lcsm
onconius.com/blog-1/5sttgd5f…
Onconius retweeted
Los anticuerpos conjugados asociados a inmunoterapia llegan a la primera línea de tratamiento en cáncer de vejiga avanzado
#emfortumabvedotin #pembrolizumab @AstellasEurope @AstellasUS @MSDEspana @msd
onconius.com/blog-1/los-anti…
Onconius retweeted
Subcutaneous atezolizumab (as opposed to IV therapy) is approved in the UK by the MHRA. It’s faster delivery for patients and reduces the increasing burden on systemic therapy units in cancer centres. It’s particularly relevant in the adjuvant setting. england.nhs.uk/2023/08/nhs-w…
Onconius retweeted
The latest update of the MONALEESA-3 trial is just published on @BCRJournal, reporting the longest OS to date for 1L patients in a phase 3 ABC trial (median OS with fulvestrant + ribociclib: 67.6 months).
breast-cancer-research.biome…
Onconius retweeted
Adjuvant alectinib improves DFS vs chemotherapy in pts after resection of a stage IB to IIIA ALK+ NSCLC . Results of phase III trial ALINA spkl.io/60134l8TL. Impact on OS, rate of cross over and brain mets incidence to be followed. Likely to be a new SoC. @ALKPositiveinc
Onconius retweeted
PARP inhibitor + AR signaling inhibitor combinations: Will this be the future of #mCRPC first-line therapy? #LibraryResource @RKSayyid @UofT and @zklaassen_md @GACancerCenter discuss data from the #PROpel, #MAGNITUDE, and #TALAPRO2 trials on UroToday > bit.ly/46w5Pfc
Onconius retweeted
Oncology is a demanding profession, asking a great amount of those practicing in the field. Oncology clinicians can set boundaries while still meeting ethical practice standards. Setting boundaries may ultimately allow clinicians to be more present & engaged while working, have more satisfaction with their work, & maintain personal well-being. Some great suggestions in this table & article ascopubs.org/doi/full/10.120…
Onconius retweeted
GECP: un Plan de Medicina de Precisión ambicioso y viable a corto plazo - Gaceta Médica - goo.gl/alerts/jGAWrU #GoogleAlerts
Onconius retweeted
#ESMO23 📢 Abstract authors & titles now online. Head to the programme & check out all the impressive science you can look forward to. While you are there, register now & benefit from reduced rates 👇
ow.ly/FXpO50Pkoq5
@AndresC27622123 @Silke_Gillessen #MedOnc
Onconius retweeted
Pooled analysis @ESMO_Open of trastuzumab deruxtecan (T-DXd) in 1970 patients with breast cancer showed incidence of ILD was 11.7%; dose dependent - 22.7% at 6.4mg/kg and 9.3% at 5.4mg/kg. Decreased LVEF seen in only 1.95%. QT prolongation in 7.8%.
esmoopen.com/article/S2059-7…
Onconius retweeted
Consulta el paper 'Medical oncology workload, workforce census, and needs in Spain: two nationwide studies by the Spanish Society of medical Oncology', 2 estudios SEOM sobre cargas de trabajo en Oncología Médica, situación laboral y necesidades en España
mcusercontent.com/b0d8b14b09…
Onconius retweeted
Just out 📢 The ESMO #GastricCancer Living Guideline. Updates in 1st-, 2nd- & further lines of tx of advanced/metastatic unresectable #OesophagealCancer, #OesophagogastricJunctionCancer & #GastricAdenocarcinoma; & supportive care & nutrition.
🔗 ow.ly/WIWP50PmrlK
#esocsm
Onconius retweeted
36% of cancer patients have “serious sexual problems” - Nation World News - goo.gl/alerts/c4pzhk #GoogleAlerts
Onconius retweeted
Report @ESMO_Open shows neoadjuvant therapy did not alter PD-L1 expression. Compared PDL1 from baseline biopsies with surgical specimens from 4 @SAKK_ch studies of neoadjuvant chemo, chemoradiation, or chemo + durvalumab and no significant differences.
esmoopen.com/article/S2059-7…
Onconius retweeted
ESMO has launched the Living Guideline for #mCRC which helps clinicians to incorporate the latest cancer research into their clinical practice, such as using trifluridine-tipiracil-bevacizumab in the third-line setting.
ow.ly/T1aX50PawnY
Onconius retweeted
Looking forward to discussing the relative merits of targeted therapy for unresectable stage III NSCLC with Dr. @JPatelMD - and learning from all the Atlanta Lung Cancer Symposium faculty on October 28, 2023 including Drs. @JhanelleGray and Sibo Tian!
bioascend.com/atlanta-lung-s…
Onconius retweeted
📘 Publicada la Guía Clínica SEOM-GOTEL sobre linfoma difuso de células B grandes (2022)
@grupolinfomas
link.springer.com/article/10…



























