Associate Professor @ University of Pittsburgh School of Medicine, Director, Health Sciences Sequencing Core Director, MIDS Program

Pittsburgh, PA
Joined September 2017
Excited to present SpaceTravLR, a new framework to uncover functional spatial microniches across contexts. We learn how individual & combinatorial genetic changes rewire regulation & cell-intrinsic + cell-extrinsic signaling across space in tissues. biorxiv.org/content/10.1101/… (1/2)
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Do you know an undergrad at @PittTweet, @ChathamU, or @CarnegieMellon who hasn't had opportunities for hands-on research? Please encourage them to apply for the Microbiology and Immunology Departments (MID) Scholars Program! Learn more and apply: lnkd.in/eT-gYTqR
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Thrilled to share my promotion to Associate Professor with tenure at @pitt_immunology! Huge thanks to my incredible lab, collaborators, department, colleagues, family & friends. Science is a team effort, and I'm so proud of our work & excited for what's next! Stay tuned!
Congratulations to Dr. Amanda Poholek @poholeklab for her promotion to Associate Professor with tenure! Learn more about Dr. Poholek and her research: buff.ly/q14wey8
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Calling @PittTweet @ChathamU @CMU_Bio undergrads interested in immunology and microbiology! Applications for @MIDSProgramPitt Scholars are due Jan 15th! Providing PAID research experiences for those from diverse and underrepresented groups. pmi.pitt.edu/research/mid-sc…
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Have a look at our new #preprint on @researchsquare: Early life RSV infection as a preventable risk factor for asthma researchsquare.com/article/r… Contains epidemiology on entire Danish population, 24000 hospital admissions for RSV and causality experiments in mouse model
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Congratulations 🎉 to @BcellBruno from @Pitt_PMI for receiving the distinguished mentor award this year from @somgradpitt ! Very well deserved!
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Your weekly reminder: we are CLUSTER HIRING 3-5 investigators into the Tumor Microenvironment Center here at @UPMCHillmanCC! Open call - if you think you’d fit in with our team, send me your application materials! Beautiful new labs, stellar community, and competitive startup!
Replying to @DelgoffeLab
I’m excited to announce that the TMC has received support to conduct an open rank (tenure-track or midcareer) cluster hire of 3-5 investigators interested in unraveling features of the tumor microenvironment to propel the understanding and treatment of cancer. 2/
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Super fun collaboration with @poholeklab now out in Nature Immunology - nature.com/articles/s41590-0… . We use interpretable #machine_learning to help identify spatial microniches of IL2 in a murine model of allergic #asthma.
What a week with two publications from our lab! Spatial microniches of IL-2 drive lung migratory Th2 cells to allergens in NI & a review on Systems Immunology Approaches to studying T cells in npj Systems Biology. nature.com/articles/s41590-0…
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Check out our new paper and let me know if you are interested in using the Fth1-mScarlet mice. journals.aai.org/jimmunol/ar…
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Happy publication day for us! Labor of love with @CoffmanLab #TLS #ovariancancer @UPMCHillmanCC @PittTweet The activity of tertiary lymphoid structures in high grade serous ovar... sciencedirect.com/science/ar…
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What a week with two publications from our lab! Spatial microniches of IL-2 drive lung migratory Th2 cells to allergens in NI & a review on Systems Immunology Approaches to studying T cells in npj Systems Biology. nature.com/articles/s41590-0…
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and to my former postdoc Kun He and all co-authors - tremendous help from collaborators Jishnu Das @jishnu1729 Bart Lambrecht @bart_lambrecht Anuradha Ray, Casey Weaver, and Wei Chen.
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2 weeks left to apply for @MIDSProgramPitt Scholars. PAID research experiences for @PittTweet @ChathamU @CMU_Bio undergrads from diverse and underrepresented groups interested in immunology and microbiology. Info and link to application: pmi.pitt.edu/research/mid-sc…
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We describe that Il-9 and Il-21 have partially overlapping and synergistic effects in asthma. Check out doi.org/10.1016/j.jaci.2024.… Nice collab with @BenjaminMedoff in MGH and @argenxglobal Revive Il-9 !
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Excited to share our paper out today in @CellCellPress with @BcellBruno @Vignali_Lab! Part of a trio of papers, we show in #Melanoma, anti-PD1+anti-LAG3 therapy modifies CD8 differentiation to promote enhanced effector function tinyurl.com/2ap5w9va
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Calling @PittTweet @ChathamU @CMU_Bio undergrads interested in immunology and microbiology! Applications for @MIDSProgramPitt Scholars opens today! Providing PAID research experiences for those from diverse and underrepresented groups. pmi.pitt.edu/research/mid-sc…
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📣Our lab is recruiting, help us spread the word! 📣 We are offering a (paid) Master student position in computational biology to study with us the role of epigenetic modifications in Arthritis. Check our job ad on the link below👇 lnkd.in/diztpFeK
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Congrats to our very own Tim Hand, PhD, for his Ascending Star Award from the University of Pittsburgh! Read more here and support Tim at his guest lecture on July 18th! pediatrics.pitt.edu/news/han…
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PoholekLab retweeted
Please RT!!! We are looking for an experienced "Research Investigator" to join a collaborative team in our lab on developing novel approaches to mitigate toxicity and enhance efficacy of cancer therapeutics by modulating nutrient metabolism. Apply here: schooljobs.com/careers/cshl/…
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