Associate Professor at the Division of Hematology & Oncology @UABHeersink @ONealCancerUAB. Exploring epigenetics in cancer and stem cells.
Birmingham, AL
Joined May 2009
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Rui LU retweeted
Online Now: Chromatin-bound U2AF2 splicing factor ensures exon inclusion dlvr.it/TKVRpb
Rui LU retweeted
On April 30, Dr. Barry Sleckman, Director of @ONealCancerUAB, testified before the U.S. Senate Appropriations Committee during the Biomedical Research: Keeping America’s Edge in Innovation hearing. Watch his powerful testimony: (starting at 52:00) appropriations.senate.gov/he…
Happy to share that our new study, "Epigenetic Regulation of Non-canonical menin Targets Modulates menin Inhibitor Response in Acute Myeloid Leukemia" has been published as the cover article in the latest issue of @BloodJournal. authors.elsevier.com/sd/arti…
A wonderful collaboration among the labs of Ravi Bhatia @RaviBha65448036, Kristin Hope @drkristinhope, and Changde Cheng, led by our talented graduate student Xinyue Zhou @xinyuezhou28. 🥂
And thanks to Ani Deshpande for the nice commentary: ashpublications.org/blood/ar…
Rui LU retweeted
It is bittersweet to say farewell to Seth Landefeld and wish him well on his next endeavor
During his time as chair of @UABDeptMed @UABHeersink he has established a path of excellence. His visionary leadership & dedication have left a mark on UAB, inspiring growth & innovation
Rui LU retweeted
Demis -- I think AlphaFold3 is really exciting. As Reviewer #3, I got great results from the server. I tried hard to get @Nature to urge you to release the code but was unsuccessful. I did not get it for re-review so I don't know if you responded. So why no code? @GoogleDeepMind
Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
Way to go! Congratulations, Xinyue!
👏 Let's give it up for graduate student Xinyue Zhou, who works in the lab of @ruilulab, for receiving the 2023 @ASH_hematology Abstract Achievement Award! She will present her work at the ASH annual meeting next week!
🎉 Congratulations, Xinyue!
Rui LU retweeted
Outstanding science and collaborators at our @TheMarkFdn retreat!
Look for our science coming soon! @FerrellLabVUMC @StanleyCLee @ruilulab
Rui LU retweeted
Breaking news: @NIH selects @DrJeanneM as director of the National Institute of Allergy and Infectious Diseases uab.edu/news/people/item/136…
Rui LU retweeted
🤗 On this #FeelGoodFriday we're thrilled to congratulate GBS student @SajesanAryal for being named a 2023 @ASH_hematology Graduate Awardee to pursue his research in the lab of Dr. Rui Lu.
We're so proud, Sajesan! Keep up the excellent work! @ONealCancerUAB @ruilulab
Big congrats to my student @SajesanAryal for being selected by @ASH_hematology to receive the ASH Graduate Hematology Award (AGHA) [loom.ly/t7i8IC4]! So proud of your work and achievement! @UABDeptMed @UAB_GBS #ASHAwards #proudPI
Deeply humbled and honored to receive the Graduate Hematology Award from @ASH_hematology. Heartfelt thanks to @ruilulab, whose mentorship has been a source of unwavering inspiration and guidance. #ASHAward
Rui LU retweeted
Do you (want to) use whole-plasmid sequencing (e.g. @plasmidsaurus) but are put off by $15/sample? Use SAVEMONEY—@MasaakiU5’s algorithm that lets you mix 6 or more plasmids/sample & computationally de-mixes reads!
colab.research.google.com/gi…
biorxiv.org/content/10.1101/…
How it works: 1/n
Rui LU retweeted
I would like to share with you our new work on the identification of the first bona fide 'reader' of #histone H3K79 methylation, which has been a mystery since the discovery of this modification in 2002.
science.org/doi/10.1126/scie…
today online in @ScienceMagazine
Rui LU retweeted
Loss of epigenetic information as a cause of mammalian aging: Cell cell.com/cell/fulltext/S0092…
Rui LU retweeted
Our work on ENTER is finally out @CellCellPress! Like📱that can 📷📞🎧, ENTER is a modular viral platform that unifies multiple applications:
⭐️Decode Ligand-Receptor interaction
⭐️Receptor-specific cargo delivery
⭐️Link receptor specificity with cell state at single cell
Rui LU retweeted
Interesting new paper with an important message - normal clone-to-clone variability is an important confounder in CRISPR experiments.
nature.com/articles/s41598-0…
Rui LU retweeted
Excited to share our latest work @nature on 3D genome organization alteration in AML. Great collaboration with Hong Zheng, @LeonidasPlatan1 @TheDoctorIsVin @rosslevinemd @YaruiDiao and many others. Led by two outstanding students @caoyuan3qiu and Fan.
nature.com/articles/s41586-0…
We are recruiting! Come and join our growing team in hematopoiesis and leukemia research in an outstanding environment @UABHeersink @ONealCancerUAB!
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Rui LU retweeted
H3K9me3 is not sufficient for silencing endogenous retroviruses if DNA methylation is perturbed. In Dnmt1 ko endoderm cells, IAP elements fully maintain H3K9me3, while trancriptionally active.
great collaboration with @LickertHeiko
out in @NatureComms
rdcu.be/cVRqS
