Veteran | World Traveler | Cultural Nomad
Joined December 2013
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KCorn retweeted
I captured this video in my lab to show the power of medicines called T-cell engagers.
Left: T cells move in and out of a cancer tumoroid, largely ignoring it.
Right: Add a T-cell engager, and the T cells attack. Once they recognize their targets, they tear through the tumor.
KCorn retweeted
The drug class we are developing, Claromers, kill nearly all known germs (bacteria, viruses, fungi, and biofilms) with one simple devastating mechanism that has avoided microbial resistance for over 200 million years.
Claromers mimic a natural defense peptide in the human body called LL-37. Each Claromer molecule is very small, only dozens of atoms big - about 1/3 the size of the natural peptide. It is like a spear - a destructive end and a holding shaft or tail end. The shaft side is hydrophobic, which means it is water-avoiding and does not like to touch water. The other side - the pathogen destroyer - is highly positively charged (called “cationic” in science literature), like a powerful magnet that pulls toward anything negatively charged (called “anionic” in science).
Stanford bioengineering Assoc Prof Barron and colleagues wrote in a recent study of Claromers: “These amphipathic peptoids self-assembled in different ways, as determined by small-angle X-ray scattering; some adopt helical bundles, while others form core−shell ellipsoidal or worm-like micelles.” That means the groups form either short twisted bundles, like worms, or small oval shapes like a football. 🏈
The self-assembly into these nano structures I. the watery fluids of the body because the water-avoiding shaft-tails point inward toward each other , away from the water. The positive pathogen-killer ends stick outward like sharpened spears. The molecules stick together on their own into tight groups.
These groups attack like a three-dimensional Greek phalanx, a tight formation of soldiers. Like a football made of spears. The spears face out. Because each molecule is so tiny its mass is almost zero. When the positive killer ends feel the pull of the germ’s outer covering they accelerate from standing still to nearly the speed of light with almost no friction, like lightning bolt ⚡️ leaping towards the pathogen. The killer-football formation hits all at once the with huge kinetic energy and blows apart the outer membrane of the pathogen.
The germ cannot survive. It is destroyed in a microsecond.
Barron and colleagues also wrote: “While self-assembly correlated overall with antibacterial efficacy... Certain self-assembled morphologies seem better-suited for antibacterial activity.” The football 🏈 hits harder.
We choose the super effective oval shapes that mass the spears for the strongest hit.
KCorn retweeted
What are we even doing if a judge can brazenly make things up to advance his own policy preferences, then invent excuses when caught, and the only consequence is removal from the case?
This should be a 435–0 vote in the House to impeach this guy, followed by his removal from the bench. Judges wield enormous power. They have the power to ruin lives, deprive people of their liberty, and make decisions that can literally mean life or death. It should be a total no brainer for every sane person that someone who abuses that power in this way has absolutely no business being on the bench.
Yet we all know what will happen. He won't be impeached and by tomorrow nobody will even be talking about it. The fact that this kinds of abuse can simply be shrugged off and forgotten tells you just how deep the rot in the judiciary runs.
KCorn retweeted
Ok, well know Meghan has come forward and has personally given a statement, then there is no room for doubt. She has said she was told of the abuse in 2018.
“I hope it can now be understood that, despite certain media publications’ distortion over the years, any distance from my father and my choice to not allow him to have contact with our children, was for one reason: to protect them. I trusted that the authorities were doing the same for other families.'
So why on earth did she not mention it in her letter to Thomas, in her Dear Daddy letter? Why not in Netflix? Why say nothing for years, when she saw nothing came from it?
If you believed your father guilty of such crimes, where by, you will not let your children meet him, why did you not follow up with authorities to ensure he is not hurting other peoples children. Are we expected to believe her hot headed husband, who runs his mouth off all the time, who spoke of the 'abuse' his family inflicted on them, wouldn't say a word?? He and Meghan have only ever said Meghan 'lost' her father because of the media intrusion and staged photos! We are expected to believe that they knew he was capable of doing such evil things and neither breathed a word until now?
She has said that the Met Police and Royalty and Special Protection department knew of it!! What next, The Royal Family knew about it but did nothing??? Because that's the vibe I am getting that she is implying here. The ROYALS knew but did nothing.
Sorry this doesn't exactly paint her in a good light either.
thesun.co.uk/news/40783001/m…
KCorn retweeted
Retired US spy satellite mysteriously explodes above earth - report
insiderpaper.com/us-spy-sate…
KCorn retweeted
The monarch butterflies you're seeing right now aren't like the ones from earlier this summer.
The previous four generations lived about two weeks, mated, and died. This one is built different. It's born knowing it won't reproduce until spring. Every calorie it takes in goes straight to fat for a 3,000-mile journey to a mountain range in Mexico it hasn't ever seen, but knows is there.
It will live eight times longer than its parents, navigate by a sun compass in its antennae, switch to magnetic sensing on cloudy days, and somehow arrive at the correct tree.
The butterfly on your goldenrod right now is fueling up. Don't spray anything near it.
KCorn retweeted
I don’t think people realize how absurd this is. Scottish runner Josh Kerr just broke the mile world record in 3:42.66, an average speed of 16.2 mph. Most people couldn’t even briefly reach that speed, let alone sustain it for an entire mile.
KCorn retweeted
Your bird bath might be missing half its potential users at best, and at worst might be drowning them.
Pollinators and smaller songbirds enjoy a good drink on a hot day from a bird bath, but many can't safely drink from standard bird baths. The water is too deep, the edges are too slick, and they can't land safely.
Bees wind up drowning in them, butterflies avoid them, and smaller birds like chickadees and finches wait for a puddle instead.
The fix? A few large rocks. Even a single rock in the center of your bird bath breaks the surface of the water and turns your bird bath into a more usable piece of habitat.
With rocks in place, bees can land and drink safely. Butterflies can perch. Smaller birds have a safe resting spot.
It doesn't cost anything if you're good at looking for rocks, takes about 30 seconds to do, and it likely doubles who can use your bird bath.
KCorn retweeted
Swiss farmers planted flowers between their crops and watched pest damage drop by over half. The UK is now running the same trial across 15 farms. The reason this works is embarrassingly simple.
A Swiss study on winter wheat found that fields with wildflower strips had 40 to 53% fewer leaf beetle pests than fields without. Crop damage dropped 61%.
The mechanism is simple. Wildflowers feed hoverflies, lacewings, parasitic wasps, ladybugs, and ground beetles. Those insects eat the aphids, beetle larvae, and caterpillars that farmers would otherwise spray for. A few meters of wildflowers hosts an unpaid pest control crew that would jump at the chance to whoop some aphid ass.
In apple orchards where no insecticides had been used for five years, plots with wildflower alleyways had 9.2% damaged fruit. Control plots without flowers had 32.5%.
The UK is now running a five-year trial across 15 farms placing 6-meter flower strips through the middle of fields, not just at the edges, because the beneficial insects can't reach the center of a large field otherwise.
This works the same way in a backyard vegetable garden as it does on a commercial farm. Plant native flowering species near your tomatoes, beans, and squash. The pests still show up, but the predators show up too.
Study doi: 20151369
KCorn retweeted
This is what happens when the food supply chain becomes too top heavy. This grower can have beautiful, ripe fruit and consumers are still paying premium prices at the grocery store. This is because the farmer has to sell into a system of limited packers, distributors, and retailers that has become massively consolidated. It’s just like beef and chicken. We need a market for the small guys; government can reduce those barriers and investment will come.
Nectarine farmer in California is giving away his entire 125,000 lbs of ripe nectarines to the public for free
He says Big Agriculture in California has made it impossible for him to harvest and sell his nectarines
You can go pick for free from June 29–July 3, at 21500 E. Parlier, Reedley, California. 7am-10am
What’s happening is a handful of large marketers and packers dominate, they are squeezing independent growers
Direct-to-retail attempts often get countered aggressively. The big companies severely undercut farmers like this to drive them out of business
KCorn retweeted
We're seeing increasing activity from the convergent shear zone separating the Middle East from the Indian Subcontinent. A cluster of activity in Pakistan and a magnitude 6.1 reverse thrust earthquake in northern Afghanistan. A bigger earthquake may be coming for the region...
KCorn retweeted
A series of powerful earthquakes struck around the globe within a 12-hour span on Wednesday, with significant quakes recorded in California, Venezuela and off the coast of Japan. 🌎
KCorn retweeted
She sold her brand to Estée Lauder at 37 and signed a 25-year ban on working. At 63 she launched a new brand on the exact day the contract ended.
"I got fired from Estée Lauder. And it was the best thing that ever happened to me," says Bobbi Brown.
When she sold the first company she said: "I won't want to work when I'm 60."
The day after the ban ended she launched Jones Road Beauty, now a $1 BILLION empire.
"Watch this 24-minute interview and you'll learn how getting fired can become the best thing in your life, and why at 63 you can start all over again, even better than at 30" ↓
Two brothers nearly brought down the entire Western financial system
they bought 200 million ounces of silver, half the world's annual production
the price jumped from $2 to $50 per ounce. their stash was worth almost $10 billion
then COMEX simply switched off the "Buy" button for everyone except the insiders
it's like GameStop, except the "Buy" button was yanked by every single broker at once
regulators kept changing the rules on the fly until the brothers went bankrupt. and the very people who forced the liquidation were sitting in massive short positions themselves
in 18 minutes you'll see how two guys almost repeated 1929 ↓
KCorn retweeted
From the Gabbard files, "Position paper about the possible origin of the SARS-CoV-2 coronavirus"
The authors of the investigation assert that the coronavirus was created in the Laboratory of Special Pathogens and Biosafety (city of Wuhan) to demonstrate to the USA the outstanding results achieved by Chinese scientists in the study of viruses. Following the accidental infection of the indicated laboratory researcher, the infection spread, causing the epidemic...
The PRC officially refutes the indicated information. However, the authorities of China, upon the appearance of the first cases of COVID-19 infection, when still nothing it was officially known about the disease, took unprecidented measures for the non-admission of the propagation of infection (declaration of total quarantine, the notification of the population regarding the danger of infection), and also the elimination of unnecessary witnesses and elimination via arson of the place of the assumed initial infection, a market for sea products, which also indirectly confirms assumption about the artificial origin of the virus of SARS-CoV-2.
Thus, in the course of the conducted primary theoretical and experimental investigations, on the basis of the analysis of the genomes of the enumerated corona viruses, and taking into account circumstantial confirmation, there is a high probability of a laboratory-produced genetically altered variant - SARS-CoV-2, for example, from the corona virus of the bat of BatRaTG13, by replacing the nucleotide sequence of the S-protein of parental strain in the sequence of the S-protein of the MT084071.1 strain of the coronavirus of the mammalian pangolin, or by the difficultly demonstrated target localized single nucleotide replacements with the use of laboratory technology CRISPR-CAS9. In this case, in the stage of conducting repeated laboratory passages of the SARS CoV-2 virus on the culture of the specific cellular line obtained from the eukaryotic cell of Eptesicus Fuscus (large brown bat), in the RNA-virus genome occurred random 12 nucleotide insertions of the misc - RNA fragment.
From the Gabbard files: "Just saw this video online. It’s from a 2016 NY Academy of Medicine meeting where Daszak (@PeterDaszak) talks about his colleagues in China manipulating the spike protein on coronavirus to make them more virulent."
KCorn retweeted
🦔Hackers stole high-profile Instagram accounts including the Barack Obama White House account, the Chief Master Sergeant of Space Force, and Sephora by typing a sentence into Meta's AI support chatbot asking it to change the email on the target account. The bot sent a verification code to the attacker's email, the attacker entered it, and got a password reset. The exploit worked for months.
In March, Meta rolled this AI support out to all Facebook and Instagram accounts with password reset authority and no option to escalate to a human. Their own blog post promised the AI could "prevent an account takeover."
My Take
Meta just cut 2,212 people from Menlo Park, gutted its core engineering teams, and handed account security to a chatbot that couldn't tell the difference between an account owner and a stranger. The hackers didn't need a sophisticated exploit. They typed a request and the bot complied.
An infosec professional in the 404 Media thread made a point worth repeating. LLMs are not deterministic. You can't secure them the way you secure traditional software. You add a second AI layer to check the first one and you've just moved the vulnerability up the chain while adding more attack surface. There's no configuration that turns a language model into a security system.
Meta gave the bot password reset authority because it was cheaper than paying humans to do support. The Obama White House Instagram got taken over because a chatbot said yes to a stranger. That's what it costs to replace your support team with software that agrees with everyone.
Hedgie🤗
404media.co/hackers-simply-a…
KCorn retweeted
This Memorial Day, we honor the service and sacrifice of the brave Americans who gave their lives for this great nation.
We will never forget their courage, their devotion, and the freedoms they fought to defend.
KCorn retweeted
To those of us who wore the uniform, Memorial Day is not about the long weekend. It's a day marked by silence, by memories, by the weight of names we carry with us.
We remember the faces -- some young, some weathered -- that never made it home. We remember laughter in the barracks, the sound of boots in gravel, the quiet moments before missions. We remember the ones who stood to our left and right -- and who gave everything.
They were not just Soldiers, Marines, Sailors, or Airmen. They were friends. Brothers. Sisters. The heartbeat of something greater than themselves.
The day is not about us -- it’s about them. And while the world carries on with barbecues and beach days, we pause. We reflect. We honor the debt that cannot be repaid, only remembered.
May we live lives worthy of their sacrifice.
KCorn retweeted
One native plant in your yard does more than 10,000 at the garden center.
Most native bees can only forage within 100 to 500 meters of their nest. They can't reach the wildflower meadow across town. Your yard is either inside their range or it isn't.
One bee balm, one coneflower, one blazing star, one mountain mint, planted in a yard that didn't have it before, is the difference between a bee finding food and a bee not eating that day.
Multiply that by every yard on your street and you've built a corridor.
The leverage isn't in the count so much as the location.
Plant one native this spring. And maybe grab an extra for your neighbor.
KCorn retweeted
Recently I visited Missouri and stayed w my mom, who grudgingly let my dogs stay too
Hub took them running and they came back with THOUSANDS of seed ticks
I fully panicked bc we were at my moms who already didn’t want the dogs there and there were SO MANY TICKS.
I put a little geranium oil on the dogs necks and the ticks literally all fell off dead and within minutes.
TRY geranium essential oil.
It is toxic like the vets meds are, so only a drop for ur animals on the back of the necks.
