Northwest Biotherapeutics. $NWBO Curing cancer by activating our own immune systems outside of the body and training them to recognise the cancer, and then re-injecting cancer killing cells. This is working on glioblastoma - one of the very hardest to treat cancers. The technique works on all solid tumours. My one position I could see being a 100x to 1,000x. MHRA approval in the UK is apparently imminent - then I expect that all hell breaks loose on the share price!

$NWBO Who’s the biggest threat to America? A- @MartinShkreli B- @citsecurities @VirtuFinancial C- @SECGov

We initially did try ivermectin and Mebendazole as fenbendazole doesn’t cross the BBB. We did metformin, CBD, all kinds of supplements and off-label drugs, hyperbaric oxygen, in addition to alternative treatments. Ultimately, her tumor grew back very aggressively. We stopped all of those treatments. After three injections of DCvax-L by $NWBO she now has a clean MRI with no evidence of disease.

Three weeks later, I still have trouble believing I was able to write these words: NO EVIDENCE OF DISEASE. 🙏❤️ I’m sharing this again because Braelyn’s story is about so much more than one incredible MRI. It’s about what can happen when someone refuses to accept that there are no more options. Please read her story. And please share it. There are other families who need to know that “there’s nothing more we can do” does not always mean there is nothing more that can be done. $NWBO #DCvaxForBraelyn

W.T.F @MHRAgovuk I’m Thomas & so far I’ve thrived for 11 years & 5 months after being administered the DCVax. Another long tail survivor has made it 27 years, & there’s also a 15 year long tail survivor. How much proof do you need. I guess you’re just as corrupt as America 🇺🇸. I thought 💭 you were better than us, I guess I was wrong 😑.

This should be blowing up the internet!

And it's only a matter of time before her case helps the world to recognize NWBO and it's vaccine DCVax-L and the potential to change how cancer is treated going forward

I have been waiting almost 3 years to write these words: NO EVIDENCE OF DISEASE. 🙏❤️ Today we met with Braelyn’s neurosurgeon, Dr. Linda Liau at UCLA (telehealth). When our local radiologist read Braelyn’s August 28 MRI as “no evidence of disease recurrence,” we were thrilled—but I was afraid to fully exhale. I knew Dr. Liau and the UCLA tumor board would scrutinize every millimeter of those images. What if they saw something the local radiologist missed? Today, Dr. Liau told us that she and the tumor board had thoroughly reviewed Braelyn’s MRI. They were amazed. There is NO VISIBLE TUMOR. Even the ~10% Dr. Liau had to leave behind during surgery because of its intimate involvement with critical structures is no longer visible. She emphasized how amazed and pleased the entire tumor board was by such a complete response at this point. Her assessment: the prior radiation and the ongoing DCVax appear to be working very well. Their recommendation after also reviewing the Keytruda regimen Braelyn recently started? KEEP DOING WHAT SHE’S DOING. 😭🙏 First and foremost, we give ALL thanks and glory to God. People all over the world have prayed for this girl. I cannot begin to express how humbled and grateful we are. But tonight I also cannot stop thinking about how close Braelyn came to never having this opportunity. Earlier this year, her tumor was enormous and growing rapidly. We sought help from multiple surgeons—including at prestigious institutions. We were told further surgery was too risky. We were offered the same old options: chemotherapy and photon radiation that would affect most of her brain, given the size of her tumor. Her tumor is MGMT-unmethylated, so for Braelyn, chemo was all risk with little to no benefit. And then a stranger I met here on X changed everything. @ThomasOwenMcCa1 connected us with Dr. Liau. After reviewing Braelyn’s case, one of the first things she said was: “This girl needs surgery right away.” I told her we knew that. We just couldn’t find anyone willing to do it. I asked if SHE would. “If you can get her to me, I will do her surgery.” We got Braelyn to UCLA. Within two weeks, Dr. Liau operated and removed ~90% of a massive tumor spanning three lobes, stopping where continuing would risk critical structures. And this time, her tumor tissue was PROPERLY PRESERVED. That tissue was ultimately sent to England and used to manufacture Braelyn’s personalized DCVax vaccine. She has now received 3 induction doses + her first booster. And today? The tumor that Dr. Liau had to leave behind is no longer visible on MRI. Think about that. And then think about what could have happened if we had simply accepted “there’s nothing else we can do.” THIS is why I will not stop advocating for reform. Patients should not have to find potentially life-saving treatment options accidentally through strangers on social media. Patients should be told about legitimate investigational options when standard treatment offers little hope. Patients undergoing tumor surgery should be informed BEFORE surgery about preservation of tissue that could potentially be used for personalized treatments. And patients should have the right to make informed decisions about which risks they are willing to take. Promising science means very little if the patients who need it cannot access it. Braelyn is living proof of why access matters. Tonight, though, advocacy can wait for just a moment. Tonight I’m her mom. And I finally get to say the words I have begged God to someday let me say: NO EVIDENCE OF DISEASE. Thank You, God. Thank you, Dr. Liau. Thank you to everyone who opened a door, donated, shared her story, fought for her and prayed for our girl. There is always light, even in the darkest places. Tonight that light is shining incredibly bright. ❤️🙏 #DCVaxForBraelyn #CureNotCovered @greta @kshaughnessy2 @andrewcaravello

These two pictures were taken 3 weeks and 3 days apart. The image on the left was taken the day before Braelyn received DCVax #3. It’s a microscopic image of Braelyn’s own dendritic cells loaded with her tumor lysate. In other words… this is the process by which her immune system is being taught to recognize her cancer. To most people, it probably looks like a boring image on a computer screen. To us, it’s hope. It represents months of surgeries, shipping tumor tissue across continents, leukapheresis, manufacturing, quality control, and the dedication of an extraordinary team of scientists—all culminating in these tiny immune cells being prepared to help Braelyn’s immune system recognize the unique targets in her tumor. I said when I first saw this image that this masterpiece deserved to be matted, framed and given a place of honor on our wall at home. Because to our family, this isn’t just science. It’s art. It’s hope. It’s Braelyn’s own immune system being given information about the enemy it needs to find. And then there’s the other picture. Three weeks and two days after Braelyn received DCVax #3, that MRI was taken. The radiologist’s conclusion: “No evidence of disease recurrence.” Her UCLA neurosurgical team and tumor board subsequently reviewed the images themselves and told us they could see no tumor tissue—including the residual tumor that had been left behind at surgery. The first picture is hope under a microscope. The second one is the image we prayed for. We know this journey isn’t over. Braelyn will continue her DCVax treatments, and we’ll continue taking things one scan, one treatment and one day at a time. But these two pictures? I think I may need to frame them together. ❤️ #DCvaxForBraelyn $NWBO @AdventBio

American medical innovation is second to none, but our current access pathways are leaving families stranded. We’ve spent over 5 weeks in London since June so my daughter could access DCVax for her brain cancer—a therapy developed in the United States. The issue isn't a lack of willingness from doctors or biotech companies; it's that current IND regulations penalize manufacturers who open their doors to critically ill patients outside of trials. When compassionate use poses a regulatory threat to a drug’s main approval path, companies have no choice but to protect their pipeline. The FDA has a real opportunity to lead here. By creating distinct regulatory protections for expanded and compassionate access, we can keep life-saving innovation—and the families who need it—here at home.

$NWBO If I'm not mistaken, Braelyn received her first dose of DCVax-L on July 22. Within about a month, after three doses, an intense anti-tumor immune response already wiped out the remaining unresected 10% of tumor tissue. The vaccine was made from her own tumor tissue, so it was a genetic match and that is why it cannot be toxic. More importantly, the DCs presenting hundreds of tumor-associated peptides on MHC Class II engage CD4 T-cells, which are essential for building immune memory. Once that memory is established, the risk of recurrence can drop dramatically. It's hard to imagine a better treatment than this — which may be exactly why approval has taken so long!

I have been waiting almost 3 years to write these words: NO EVIDENCE OF DISEASE. 🙏❤️ Today we met with Braelyn’s neurosurgeon, Dr. Linda Liau at UCLA (telehealth). When our local radiologist read Braelyn’s August 28 MRI as “no evidence of disease recurrence,” we were thrilled—but I was afraid to fully exhale. I knew Dr. Liau and the UCLA tumor board would scrutinize every millimeter of those images. What if they saw something the local radiologist missed? Today, Dr. Liau told us that she and the tumor board had thoroughly reviewed Braelyn’s MRI. They were amazed. There is NO VISIBLE TUMOR. Even the ~10% Dr. Liau had to leave behind during surgery because of its intimate involvement with critical structures is no longer visible. She emphasized how amazed and pleased the entire tumor board was by such a complete response at this point. Her assessment: the prior radiation and the ongoing DCVax appear to be working very well. Their recommendation after also reviewing the Keytruda regimen Braelyn recently started? KEEP DOING WHAT SHE’S DOING. 😭🙏 First and foremost, we give ALL thanks and glory to God. People all over the world have prayed for this girl. I cannot begin to express how humbled and grateful we are. But tonight I also cannot stop thinking about how close Braelyn came to never having this opportunity. Earlier this year, her tumor was enormous and growing rapidly. We sought help from multiple surgeons—including at prestigious institutions. We were told further surgery was too risky. We were offered the same old options: chemotherapy and photon radiation that would affect most of her brain, given the size of her tumor. Her tumor is MGMT-unmethylated, so for Braelyn, chemo was all risk with little to no benefit. And then a stranger I met here on X changed everything. @ThomasOwenMcCa1 connected us with Dr. Liau. After reviewing Braelyn’s case, one of the first things she said was: “This girl needs surgery right away.” I told her we knew that. We just couldn’t find anyone willing to do it. I asked if SHE would. “If you can get her to me, I will do her surgery.” We got Braelyn to UCLA. Within two weeks, Dr. Liau operated and removed ~90% of a massive tumor spanning three lobes, stopping where continuing would risk critical structures. And this time, her tumor tissue was PROPERLY PRESERVED. That tissue was ultimately sent to England and used to manufacture Braelyn’s personalized DCVax vaccine. She has now received 3 induction doses + her first booster. And today? The tumor that Dr. Liau had to leave behind is no longer visible on MRI. Think about that. And then think about what could have happened if we had simply accepted “there’s nothing else we can do.” THIS is why I will not stop advocating for reform. Patients should not have to find potentially life-saving treatment options accidentally through strangers on social media. Patients should be told about legitimate investigational options when standard treatment offers little hope. Patients undergoing tumor surgery should be informed BEFORE surgery about preservation of tissue that could potentially be used for personalized treatments. And patients should have the right to make informed decisions about which risks they are willing to take. Promising science means very little if the patients who need it cannot access it. Braelyn is living proof of why access matters. Tonight, though, advocacy can wait for just a moment. Tonight I’m her mom. And I finally get to say the words I have begged God to someday let me say: NO EVIDENCE OF DISEASE. Thank You, God. Thank you, Dr. Liau. Thank you to everyone who opened a door, donated, shared her story, fought for her and prayed for our girl. There is always light, even in the darkest places. Tonight that light is shining incredibly bright. ❤️🙏 #DCVaxForBraelyn #CureNotCovered @greta @kshaughnessy2 @andrewcaravello