@sneakystaph

Postdoctoral Researcher in the Lewis lab, @Northeastern University #diggingfordrugs

 Boston, MA
Joined May 2016
  • Tweets419
  • Following147
  • Followers226
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Exciting news! Our latest discovery of bacterial danger sensing is featured in TWiM episode 326! Huge thanks to @TWiMSchmidt, Prof. Michele Swanson, & Prof. Vincent Racaniello for their amazing insights. Listen here 🎧👇 #microbiology #biofilms #twim asm.org/Podcasts/TWiM/Episod…

I Have One Word For You: PETase!

The discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation.

asm.org
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Samay Pande@iamsamayp21 Feb 2025
New paper alert!!🎉🥁🚀🎉 Survival of the resistant: When Myxococcus xanthus dies, antibiotic-resistant microbes rise, even without drug exposure. Our manuscript is now online at @CurrentBiology 🚀📕📗 sciencedirect.com/science/ar…
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Knut Drescher@knutdrescher6 Jan 2025
We found that many bacterial species use exogenous peptidoglycan fragments - released by lysis of neighboring cells - as a general danger signal, triggering a danger response that protects bacteria against many dangers: biofilm formation. Details👇: nature.com/articles/s41564-0…

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation

Nature Microbiology - Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

nature.com
Nature Microbiology@NatureMicrobiol3 Jan 2025
OUT NOW: Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation @knutdrescher @sneakystaph @biozentrum nature.com/articles/s41564-0…

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation

Nature Microbiology - Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

nature.com
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Kicking off the new year with my paper on danger sensing in bacteria! Discover how bacteria defend against phage attacks. Huge thanks to everyone who contributed! #biofilms #phage #dangersensing
Nature Microbiology@NatureMicrobiol3 Jan 2025
OUT NOW: Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation @knutdrescher @sneakystaph @biozentrum nature.com/articles/s41564-0…

Bacteria use exogenous peptidoglycan as a danger signal to trigger biofilm formation

Nature Microbiology - Peptidoglycan released by neighbouring kin or non-kin cell lysis induces physiological changes that protect from a range of stresses, including phage predation.

nature.com
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Jörg Vogel@JoergLab27 Oct 2023
This is truly unique PhD programme: train in both RNA biology and infection biology. Fully funded position. Spread the word!
Helmholtz Institute Würzburg (HIRI)@Helmholtz_HIRI27 Oct 2023
🚨 Open #PhD positions 🚨 The Helmholtz Institute Würzburg is looking for motivated PhD students who are interested in working at the interface of #RNA and #infection biology. Apply by December 10 at helmholtz-hiri.de/en/jobs-ta… Learn more about our #graduate program in this thread 🧵
Photo: HIRI / Sandy Westermann (SCIGRAPHIX)

ALT Photo: HIRI / Sandy Westermann (SCIGRAPHIX)

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Jeremy J Barr@JeremyJBarr27 Oct 2023
Our latest work, out today in @PLOSBiology suggests that not only do mammalian cells absorb bacteriophages, but they appear to use them as a resource to enhance growth! journals.plos.org/plosbiolog… This work was led by @marion_bichet and out on World Phage Week! #WorldPhageWeek

Mammalian cells internalize bacteriophages and use them as a resource to enhance cellular growth...

There is a growing appreciation that the direct interaction between bacteriophages and the mammalian host can facilitate diverse and unexplored symbioses; this study shows that mammalian cells...

journals.plos.org
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nature
@Nature18 Oct 2023
Nature research paper: Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs go.nature.com/3QmVDPY

Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs

Nature - In response to bacterial CRISPR–Cas immunity, phages and plasmids have evolved small non-coding RNA anti-CRISPRs, known as Racrs, that sequester Cas proteins in abberrant complexes...

nature.com
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Had a wonderful time at ICARe! Thanks to the organisers and all attendees for such a fabulous time and stimulating science. – at Annecy, France
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Exciting to have our latest work out! We found 2 novel PET-degrading enzymes and show that increasing biofilm can increase degradation @McCarthy_Ronan @Nature_NPJ @BrunelResearch @RecoverBBI @NERCscience nature.com/articles/s41522-0…

Modulating biofilm can potentiate activity of novel plastic-degrading enzymes

npj Biofilms and Microbiomes - Modulating biofilm can potentiate activity of novel plastic-degrading enzymes

nature.com
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Knut Drescher explaining how bacteria use exogenous peptidoglycan as a danger signal to trigger protective biofilm formation. @knutdrescher
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What a great experience to present at #ASMicrobe !
Julia van Kessel@Biolluminator17 Jun 2023
Very proud to hear my former student @sneakystaph talk about her research at #asm
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So glad to be attending ASM Microbe! Come by room 342 on 06/17 at 3 pm to hear about bacteria sense danger to fight off phages! #ASMicrobe
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When you are doing an RNA extraction and lose the pellet
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Elisa Granato@Prokaryota15 May 2023
bröther what have they done to you
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😳 Bacterial spore germination receptors are nutrient-gated ion channels: 👇🏿👇🏿👇🏿 science.org/doi/10.1126/scie…

Bacterial spore germination receptors are nutrient-gated ion channels

A class of ligand-gated ion channels release cations in response to nutrients to initiate exit from spore dormancy.

science.org
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Prepping for a class session on the Lac operon in Molecular Biology and it prompts my yearly reminder to you all that what we were taught about the actual substrate of the Lac operon is almost certainly wrong...1
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Happy World Kombucha Day! 🍵 #worldkombuchaday worldkombuchaday.com/
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SourjikLab@sourjik24 Dec 2022
I think it's our first paper that was published on Christmas Eve! Maybe it's because of Giovanni's @G_Scarinci images that look like Christmas decoration. nature.com/articles/s41396-0…
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Mathias supervised my BSc and MSc projects, and I can vouch for him and his lab; It’s a great place! So if you interested in phages I would strongly recommend that you apply for this position :)
Mathias Middelboe@mmiddelboe115 Dec 2022
A new PhD position in "Bacteriophage-pathogen interactions" is now open at Marine Biological Section, University of Copenhagen: candidate.hr-manager.net/App…
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Robust fluorescent proteins for high-resolution microscopy and biochemical techniques | Nature Methods nature.com/articles/s41592-0…
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