@yllidok
Joined October 2009
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ylli doksani retweeted
Lu Chen@luchenlab_FCCC24 Mar 2023
Telomere is a hotspot for replication fork reversal- genotoxic "chicken-feet" hard to resolve by cells and by biochemists. W/ @DoksaniLab @FoxChaseCancer, we show reversed telomere fork is directly extended by telomerase, a usual guardian turning to a foe. science.org/doi/10.1126/scia…

The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats

Fork collapse during replication of telomeric repeats generates 3'-DNA ends that are elongated by telomerase.

science.org
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My PhD advisor Susan Lovett was just inducted into NAS. She has never had a CNS paper. Let it be a lesson to those who think that’s what it takes to “stand out”. No. It’s about fundamental contributions to science (she did it using bacteria btw for the haters 😉😛). Love Sue.
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ylli doksani retweeted
Doksani Lab@DoksaniLab8 Apr 2022
If you want to go down the rabbit hole of #Telomere #biology and need to purify #Telomeres, here’s a protocol for you. From Doksani lab, with love: nature.com/articles/s41596-0…
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