Bioinformatics scientist @AllenInstitute. PhD in computational biology from @BrownCCMB @BrownUniversity. Previously at @illumina. he/him

Seattle, WA
Joined August 2018
Alan DenAdel retweeted
A phenomenal team-lead opportunity at the new @AllenInstitute AI BioDesign accelerator, please feel free to share to potential applicants!
7
17
3,072
Come work with us and be our colleague!
If you'd like to come work with me and my amazing colleagues as a full-time researcher @MSFTResearch @MSRNE, please apply here: apply.careers.microsoft.com/… apply.careers.microsoft.com/…
6
18
1,686
Alan DenAdel retweeted
If you'd like to come work with me and my amazing colleagues as a full-time researcher @MSFTResearch @MSRNE, please apply here: apply.careers.microsoft.com/… apply.careers.microsoft.com/…
2
18
5
134
14,130
Our biggest win (so far!) with [auto-optimize]
MACS 3.1.0 is released with a jaw-dropping 40-60x improvement in speed, thanks to @jmschreiber91's auto-optimize work! AI achieved in one weekend what I've been hoping for years! Now peak calling that once took minutes can be completed in seconds! github.com/macs3-project/MAC… 1/2
3
28
2,459
Alan DenAdel retweeted
Join @FlatironInst @SimonsFdn as a Research Fellow in NYC 🚀 Lead cutting-edge work in computational science & ML with top collaborators. Apply by Nov 15: apply.interfolio.com/193799 More on ML@CCM 👉 users.flatironinstitute.org/… Keen to work with folks in #AIforScience & #GenerativeAI
13
48
3,832
Calling graduate students 📣. Come work on AI x Bio @MSFTResearch 🎉! We are currently recruiting graduate student interns for summer 2027! Apply and come work with me on problems in regulatory genomics, epigenomics, biosecurity, and wearables!
Are you a PhD student interested in the intersection of machine learning and biology or healthcare? Come do an internship with the BioML Group at MSR! Make sure you submit a research statement! apply.careers.microsoft.com/…
8
44
4,124
That time of the year again! I and others on the team are recruiting graduate student interns for next summer! Please share with anyone who might be a good fit and don’t hesitate to reach out if interested: apply.careers.microsoft.com/…
Are you a PhD student interested in the intersection of machine learning and biology or healthcare? Come do an internship with the BioML Group at MSR! Make sure you submit a research statement! apply.careers.microsoft.com/…
1
2
32
2,246
Are you a PhD student interested in the intersection of machine learning and biology or healthcare? Come do an internship with the BioML Group at MSR! Make sure you submit a research statement! apply.careers.microsoft.com/…
8
46
6
276
35,087
Alan DenAdel retweeted
I am so honored to receive NIH Director's New Innovator Award for our lab!🌟 I am really grateful to our lab members and all mentors supporting me past and present. We are looking forward to exciting science we can do and relatedly, hiring at all levels!! newsroom.uw.edu/blog/3-from-…
The NIH Director’s New Innovator Award supports exceptionally creative early-career investigators pursuing innovative research with the potential for significant impact. Learn about the 2026 award recipients and their groundbreaking projects: commonfund.nih.gov/newinnova…
2
11
76
6,101
Alan DenAdel retweeted
Exciting day for DNA Typewriter w/ 2 papers from the lab & SeaHub out today :) 1. Mouse lineage from E0 to E13.5 science.org/doi/10.1126/scie… 2. A fluctuation test for gastruloid heterogeneity cell.com/cell/fulltext/S0092… Paper #1 covered in quoted thread. More on paper #2 here. 1/n
Thrilled to post thread re: new single-cell lineage of mouse embryo reconstructed w/ DNA Typewriter. One animal, zygote to late organogenesis (E13.5). Tree has 1,340,794 transcriptionally profiled, annotated tips (cells), 1,142,588 dated internal nodes, rooted at zygote 1/n
4
63
5
194
16,162
Alan DenAdel retweeted
After a long wait, tangermeme is out @naturemethods! tangermeme implements the primitives of genomic sequence-to-function modeling with efficient, tested, and composable functions. I use it every day in my work, and I hope you find it useful too. nature.com/articles/s41592-0…
7
85
3
298
19,569
Alan DenAdel retweeted
Excited to share Shotgun Genetic Engineering, developed by @julie_trolle, out in @NatureBiotech! Read on to learn how Julie enabled mammalian cells to grow without 2 essential amino acids for the first time in >500 million years using highly multiplexed metabolic engineering!
Highly multiplexed mammalian metabolic engineering with a shotgun approach - @sudpinglay @JefBoeke nature.com/articles/s41587-0…
2
13
48
5,857
NECB 2026 is bringing together close to 400 researchers 🎉 across New England at @MSFTResearch New England in Cambridge for two days of computational biology 🙌. Follow us #NECB2026
3
11
300
🎊 @BRIseattle postdoc Dr. LeAnn Nguyen was awarded the Institute for Translational Immunology Fellowship through @UW. Dr. Nguyen’s project will characterize the effects of #GeneticVariants that are linked to #AutoimmuneDiseases. Congratulations! bit.ly/3SPDheJ
1
2
151
Alan DenAdel retweeted
Science moves faster when knowledge is shared openly. From the time I entered graduate school, I became fascinated by what open sharing of data could do in fields as disparate as physics, art, and coding. Total strangers helping each other go further. Sharing knowledge openly is part of the ethos of the @AllenInstitute. Every year, millions of people use our open data and tools to power their research, to learn, and even to make art. We take on foundational projects that are needed and are too big for any single lab to tackle, and build them from day one to be shared. We need to share and work together to accelerate science for a healthier world. This #OpenScienceWeek, join me in celebrating the scientists and organizations everywhere who share their data, tools, and knowledge to accelerate discovery.
2
10
1
37
3,618
Exciting new updates to the Seattle Alzheimer’s Disease Brain Cell Atlas (SEA-AD)! Two new data sets are now available: SEA-AD Multiregion and SEA-AD CaH.
3
12
22
2,575