Biochemist, Postdoctoral fellow @Merck.
Philadelphia, PA
Joined March 2018
- Tweets104
- Following359
- Followers209
- Likes635
Our latest work from @gohillab at @TAMUBCBP got featured in Feb ‘25 issue in @GeneticsGSA. Using yeast mitochondrial protease mutants, we identified mAAA protease regulates degradation of mitochondrial magnesium channel MRS2 #mitochondria #protease
RachelStanfield
🔗👇
MRS2, a #mitochondrial magnesium channel decreases in models of Barth syndrome—an X-linked genetic disorder. In #GENETICS, @AlaumyJ, @gohillab identify the function of #yeast protease in regulating MRS2 levels, opening new pathways to study Barth syndrome. bit.ly/3DKDM1n
Excited to share my recent work uncovering the novel role of magnesium in Barth syndrome pathology. This work in @gohillab identifies essential requirement of cardiolipin for magnesium ion channel stability. Do check it out! academic.oup.com/hmg/advance…
@TAMUBCBP @hmg_journal
#mito
Alaumy Joshi retweeted
Our new study, led by @AlaumyJ, shows a critical requirement of cardiolipin (CL) for the stability of the mitochondrial Mg channel. This study uncovers a potentially novel role of Mg in the pathology of Barth syndrome, a genetic disorder of CL metabolism. academic.oup.com/hmg/advance…
Alaumy Joshi retweeted
In their Review, @AlaumyJ, Travis Richard and @gohillab @TAMUBCBP discuss the latest research on the function and transport of mitochondrial phospholipids in health and disease.
journals.biologists.com/jcs/…
ALT Cartoon showing phospholipid transport to, from and within mitochondria
Alaumy Joshi retweeted
Online now - the Review "Membrane homeostasis beyond fluidity: control of #membranecompressibility" from @MikeRenne and Robert Ernst @Saar_Uni.
#MembraneFluidity #MembraneThickness #HomeoviscousAdaptation #unfoldedproteinresponse
Read it here 👉 authors.elsevier.com/sd/arti…
Alaumy Joshi retweeted
Wonderful review by lab alum @AlaumyJ with @gohillab on mitochondrial phospholipid metabolism @J_Cell_Sci: journals.biologists.com/jcs/… Do check it out !!!
Excited to share my first review article with @gohillab in @J_Cell_Sci . Thank you for the guidance!!
@TAMUBCBP @TAMU @aglifesciences. #mitochondria #mitowomen #phospholipid #mitochondrialdisorder.
If you want to know all about the biochemistry, biophysics, biosynthesis, transport, function, and diseases of mitochondrial phospholipids in 6000 words, you can check out our review. This heroic effort of was led by @AlaumyJ in my lab. journals.biologists.com/jcs/…
What a proud moment for India!
India is on the Moon 🇮🇳.
Congratulations to India and #ISRO .
#ISROChandrayaan3 #ProudIndian
Chandrayaan-3 Mission:
Chandrayaan-3 ROVER:
Made in India 🇮🇳
Made for the MOON🌖!
The Ch-3 Rover ramped down from the Lander and
India took a walk on the moon !
More updates soon.
#Chandrayaan_3
#Ch3
Alaumy Joshi retweeted
#TAMUBCBP has several students that we would like to recognize for their hard work in a recent poster and oral presentation research competition. Please help us congratulate our students and their mentors!
bcbp.tamu.edu/biochemistry-c…
Alaumy Joshi retweeted
How we think and talk about mitochondria matters to our science and to newcomers in the field.
The powerhouse analogy is expired and we need specific vocabulary to capture the beautiful complexity of mitochondrial biology.
We propose a framework and some nomenclature.
Alaumy Joshi retweeted
We need to talk about MitoSOX...
There are a number of issues with MitoSOX/hydroethidine as "superoxide" probes.
One approach from Richard Hartley's lab and mine is to use MitoNeoD/NeoD. Give it a go and let us know if it works for you.
sciencedirect.com/science/ar…
Alaumy Joshi retweeted
For those interested in mitochondrial copper disease biology check out our recent primer on this topic. cell.com/trends/endocrinolog…
Alaumy Joshi retweeted
Thrilled to share a review from the lab @IISERPune, on photo reactive bioorthogonal lipid probes now online @rsc_chembio. Terrific work @karthikgs24 & Kavita for getting this together. pubs.rsc.org/en/content/arti…
Thanks for your mentoring and support!!
Very happy and proud of my student @AlaumyJ and many thanks to @WelchFoundation for supporting our research!
We are pleased to present the 2022 Welch Conference on Chemical Research Poster Presentation Awards to four outstanding researchers:
Faculty:
@JonesMattRob, @riceuniversity
Trainees:
@AlaumyJ, @TAMU
@aman_agrawal_92, @UHouston
Yigao Yuan, Rice University
welch1.org/
Alaumy Joshi retweeted
Today, we and @ganetzky1 report @NEJM a remarkable case of twin boys with euthyroid hyper-metabolism (low body weight despite high caloric intake), due to a de novo mutation in mito CV that uncouples respiration from ATP synthesis. nejm.org/doi/full/10.1056/NE…
Alaumy Joshi retweeted
BREAKING NEWS:
The Royal Swedish Academy of Sciences has decided to award the 2022 #NobelPrize in Chemistry to Carolyn R. Bertozzi, Morten Meldal and K. Barry Sharpless “for the development of click chemistry and bioorthogonal chemistry.”
Alaumy Joshi retweeted
#Autophagy is a major area of interest and mechanisms of microautophagy specifically are receiving growing interest. L Wang @hunanuniv, DJ Klionsky @UMich & H-M Shen @UM_1981 discuss emerging functions of #microautophagy in our latest #NRMCBReview!
📣 📣go.nature.com/3xkBksI
