I don't always run Epitalon. But when I do, it's 5 mg. For 20 days. Three times a year. Stay interesting, my friends.

Another feel good message. This time from a family member.

Does feeling nauseous after a workout ever go away, or is that just part of it?

At low, medium, and high doses, MOTS-c reduced protein leaking into the urine, one of the first signs of diabetic kidney damage. Higher doses protected more. - Treated mice had less damage to the kidney tubules (the small filtering tubes), less fat built up in kidney tissue, and fewer inflammatory immune cells moving in. - Signs of cell aging (p16, γH2AX, and SA-β-gal) went down. The study is Wang et al. in Biochemical Pharmacology (doi.org/10.1016/j.bcp.2026.1…), published online Oct 23 by a team at Central South University in China. They tested MOTS-c in two types of diabetic mice and in human kidney cells grown in a dish.

Those with a pen... did you get the 6mm tips? After this MotsC pin I'm realizing I might need a longer tip... 🖊

Accidentally click on one post I didn’t want to see and the algorithm is cooked for the next two days. Every single time....

The scariest visitor this Halloween is that free reta that showed up with no batch number....

My friend is 2 weeks in and now buying herself a mini fridge. 😆 🤣

Bruno living his best life. 💕

My optometrist lied when he said my glasses would “smudge resistant” if I upgraded. 🤓

Today was one of those workouts where I wanted to quit and no one was around to notice. Then I remembered @katieiswell showing off her guns and thought… I have to finish. My arms are watching me not quit on what they can be. 🤣

Just hit 500 followers. Thanks for letting me say what’s on my mind and for sharing your experiences with me while I figure out this health journey ✨

Quick update on my friend~ she’s got little kids and teens, was getting sick all the time, and has been in the thick of menopause while coming off birth control. She’d tell me how rough she felt pretty much every day. We’re 10 days into her protocol and for the last 4 days she’s been messaging me how good she feels. Like, actually good. SS-31, TA1, and GLP-2. 💪

With parents pulling back on sugar/candy now days will we have less trick or treaters... 🎃 🍬 🍫

Why no video yet The conference is still underway. The World Mitochondria Society typically records talks and later offers paid on-demand / replay access (they have done this for prior years such as 2023, 2022, and 2021). These are usually not free or instantly public. Check the official site for updates on recordings or abstracts: Main site / agenda: wms-site.com or the Targeting Mitochondria pages

SS31/Elamipretiden Recent Preclinical Work (2026) Spinal cord injury (mouse model): Improved locomotor recovery and gait, reduced lesion pathology, and effects on apoptosis and neural remodeling markers. Heart failure with preserved ejection fraction (HFpEF rat model): Improved skeletal muscle contractile function, reduced atrophy, and changes in titin phosphorylation and mitochondrial measures. Post-cardiac arrest brain injury and other injury models have also shown mitochondrial-protective signals. Ongoing Study, The SHAPE study (led by David Marcinek at the University of Washington with Mighty Therapeutics) is an open label pilot of elamipretide in older adults and part of the XPRIZE Healthspan competition. The team won a $1 million Milestone 2 award based on “encouraging” functional trends, though public effect size details are limited. The data are informing a larger placebo-controlled trial in older adults planned through ~2029.

After lifting I feel wrecked. After a run my legs are kinda numb but I’m wide awake and full of energy. That post run buzz is addictive. 🏃‍♀️