Wellcome Sanger Institute, Cambridge UK
Joined April 2019
- Tweets79
- Following124
- Followers620
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Cancer Dependency Map Sanger retweeted
We're recruiting a Senior Staff Scientist to map genetic interactions to understand epistasis in health and disease. Come help lead a multidisciplinary team to tackle this fundamental challenge in our understanding of genes and genomes. jobs.sanger.ac.uk/vacancy/se… #sangerinstitute
Cancer Dependency Map Sanger retweeted
Grateful to have contributed to this study mapping dependencies in OSCS from Asian patients as part of @DepMapSanger. Phenomenal work from Annie Wei & Sok Cheong @reversecancer and @sangerinstitute team @fiona_fb3 @emanuelvgo stacey price @ultanmcd @jgrgilbert #depmap
Excited to share our paper on identifying genetic vulnerabilities in oral cancer now published in @eLife. For those interested in #CRISPR and #drugdevelopment check elifesciences.org/articles/5….
Cancer Dependency Map Sanger retweeted
(1/5) We are delighted to share the updated Project Score database (score.depmap.sanger.ac.uk/) and accompanying paper @NAR_Open (academic.oup.com/nar/advance…). The Project Score database uses CRISPR screens to investigate cancer dependencies and prioritise candidate targets.
ALT Project Score homepage
Cancer Dependency Map Sanger retweeted
Elegant analysis of the mechanism underpinning WRN dependency in MSI tumours and great to see the field moving forward so rapidly. congratulations to the team involved.
Online at @nature: "Repeat expansions confer WRN dependence in microsatellite-unstable cancers" by @nussenza and colleagues. Interesting mechanistic insights into microsatellite instability and the vulnerabilities it confers to #cancer cells nature.com/articles/s41586-0…
Cancer Dependency Map Sanger retweeted
Good protocols are critical for advancing science. Thanks to the work of the technical team @sangerinstitute to produce these beautiful SOP for deriving and culturing tumour organoids. Includes tips, images and videos, all freely available. @TechsCommit #depmap @CancerDepMap
A huge effort from the team to bring you our cancer organoid derivation and expansion SOP’s. We hope you find them useful @protocolsIO @Garnettlab protocols.io/view/derivation… protocols.io/view/cryopreser… protocols.io/view/thawing-an…
protocols.io/view/derivation…
protocols.io/view/passaging-…
Cancer Dependency Map Sanger retweeted
Nice to see this summary on using @DepMapSanger to study drug MoA from @boehmjesse and @DrFranVazquez. #depmap.
N&V by @boehmjesse @broadinstitute on the study by @Garnettlab @sangerinstitute, using the Cancer Dependency Map for drug mechanism‐of‐action investigations --> bit.ly/2OMmFQ9 #CancerGenomics #Genomics #Pharmacogenomics
Cancer Dependency Map Sanger retweeted
The GDSC website (cancerrxgene.org/) has been upgraded with two new features to enhance your analysis. GDSC hosts differential drug sensitivity data across 1,000 human cancer cell lines for hundreds of anti-cancer drugs, together with genomic biomarkers of drug sensitivity.
ALT GDSC homepage
Cancer Dependency Map Sanger retweeted
This is great work by @DepMapSanger @CancerDepMap working collaboratively to bring together an integrated dataset for 800 cell lines. Have fun everyone who, like us, enjoys working with these rich datasets! #depmap #CRISPR
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Cancer Dependency Map Sanger retweeted
Our review on "Genomics-guided pre-clinical development of cancer therapies", published with @SpringerNature in @NatureCancer is now out! SharedIt link: rdcu.be/b4lxF [rdcu.be]. Many thanks to coauthors @HayleyFrancies @ultanmcd. #CancerResearch
Cancer Dependency Map Sanger retweeted
CELLector is useful new tool that mines clinical data to define molecular sub-types and then maps these onto in vitro cancer models. This can help you find the right cell model for your work. Congratulation to @HannaNajgebauer @Francesco_i0ri0 and team. Part of @DepMapSanger
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Cancer Dependency Map Sanger retweeted
My webinar on using functional genomics for cancer drug discovery is now available to view here: milner.cam.ac.uk/milner-semi…. Join me for a live Q&A at 1pm today. @DepMapSanger #depmap
Cancer Dependency Map Sanger retweeted
Open position for a Junior Group Leader in AI for Oncology at the Netherlands Cancer Institute. Feel free to get in touch ! @hetAVL @NKI_nl
More info here: jgl-ai4cancer.nl
Cancer Dependency Map Sanger retweeted
Great career opportunity as a Senior Staff Scientist in our lab (jobs.sanger.ac.uk/vacancy/se…). Help lead our efforts using functional genomics to study genetic epistasis in cancer. A diverse and challenging role with opportunity for development. Closing date March 26th. Please RT.
Cancer Dependency Map Sanger retweeted
I'm delighted to share that I have joined @targetvalidate team as Experimental Science Director and I look forward to working more closely with the fantastic Open Targets community.
opentargets.org
Cancer Dependency Map Sanger retweeted
I’m thrilled to announce the publication of the quantitive proteomic profiling of the Cancer Cell Line Encyclopedia. The @GygiLab in collaboration with colleagues at Novartis and the Broad we measured the proteomes of 375 cell lines from various tumor lineages (1/13)
Cancer Dependency Map Sanger retweeted
Do you care about #openscience, cross cutting collaborations, and cancer patient impact? Join the DepMap team! We are #hiring for a Project Coordinator, apply here: broadinstitute.wd1.myworkday…
Cancer Dependency Map Sanger retweeted
A reminder that we have an opening for a Senior Staff Scientist to help lead a team building genetic interaction maps. Closing Jan 18th. This is a great opportunity to do cutting-edge collaborative science. Don't miss out! @sangerinstitute @DepMapSanger #CRISPR #depmap
Looking to do exciting new science and progress to the next step in your career? We have a Senior Staff Scientist position available in functional genomics to help lead a team building genetic interaction maps.
(jobs.sanger.ac.uk/vacancy/se…). Part of @DepMapSanger #Depmap.
Please RT
Cancer Dependency Map Sanger retweeted
Congratulations to @Francesco_i0ri0 and @aviadt for leading this collaborative study with @DepMapSanger and @CancerDepMap teams showing agreement between two large CRISPR datasets. This lays the foundation for future integration and analysis. #depmap #CRISPR
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Cancer Dependency Map Sanger retweeted
Did Santa come early? 🎁🌟 19Q4 cancer dependency data now live!
#CRISPR knockout screening data for 66 new #cancer cell lines (our biggest increase/quarter yet!), plus accompanying gene expression, copy number and mutation profiles: depmap.org #depmap
Cancer Dependency Map Sanger retweeted
Looking to do exciting new science and progress to the next step in your career? We have a Senior Staff Scientist position available in functional genomics to help lead a team building genetic interaction maps.
(jobs.sanger.ac.uk/vacancy/se…). Part of @DepMapSanger #Depmap.
Please RT