🥽🩺Docs/nurses/pharmacists from U.K. Talking CardioRenoMetabolic & more Catch us on YouTube https://xitter.cf/t.co/VSFSwEDXDD |Educate, Motivate, Activate!

London, England
Joined October 2020
GoggleDocs retweeted
Dr Amar Puttanna 🎸@AmarPutOct 15
@NICEComms expects benefit in a frail, vulnerable cohort…. Show me the evidence… potential for harm has not been mitigated and needs to be balanced/addressed…
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🧓 Can GLP-1 RAs help preserve function in people with diabetes? In 73,592 propensity-matched pairs, GLP-1 RA initiation vs DPP-4 inhibitors was associated with: 📉 Less frailty progression 🚶 13% lower fall rate (IRR 0.87, 95% CI 0.84–0.91) ⚠️ Associations were weaker in severe baseline frailty. Real-world evidence, not proof of causality. #Diabetes #Frailty #GLP1RA #Geriatrics dom-pubs.onlinelibrary.wiley… @AskDrShashank
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🩺 HbA1c vs fasting glucose: Which better predicts cardiometabolic multiple long term conditions (multimorbidity) in people without diabetes? Our study led by @scelee1 & Setor In 2,233 adults in England followed for 12–15 years, both markers were associated with future cardiometabolic multimorbidity—but HbA1c was the stronger predictor. 📈 Each 1% higher HbA1c: ~2× higher odds 🔬 HbA1c improved risk discrimination more than fasting glucose. HbA1c help identify long-term cardiometabolic risk earlier? #Diabetes #CardiometabolicHealth #Prevention #PublicHealth sciencedirect.com/science/ar… @AskDrShashank @LDC_tweets @uniofleicester
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GoggleDocs retweeted
GLP-1 are a life changing and possibly a humanity changing group of medications. The fact that insurance will not cover them should cause patients to be extremely angry. Obesity is the mother of chronic disease. Successful obesity treatment should not be discriminated against.
It seems that GLP-1s reduce the whole-body risk of disease. Across 5 RCTs, semaglutide lowered blood-based risk scores for diabetes, and in 4 of 5 for AFIB, heart failure and coronary disease. Just fascinating!
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GoggleDocs retweeted
Colleagues, we need your help - We're seeking nephrologists' perspectives on management of iron deficiency in CKD. The survey takes <5 minutes & will help shape the design of a new international randomised trial rnsapmredcap.nslhd.health.ns… Thanks for sharing with your networks
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Next-Generation Obesity and Diabetes Therapy CagriSema — REIMAGINE 2 HbA1c reduction: 1.9% Weight reduction: 14.6% TIR increased from 52.3% to 88.0% at week 68 Retatrutide — TRIUMPH-2 Major weight reduction with accompanying improvement in glycaemic control. Survodutide — SYNCHRONIZE-2 -Significant weight loss and HbA1c reduction, -gastrointestinal adverse effects ( concerning point) Amylin-Based Therapies -An emerging major pathway for obesity treatment, -cagrilintide and eloralintide. Oral Incretin Therapies -oral semaglutide -orforglipron. Once-Weekly Basal Insulin
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GoggleDocs retweeted
Marvellous edit 😅
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GoggleDocs retweeted
Dear @Ofcom Please can you clarify to the nation why this is allowed under your current broadcasting rules? A sitting MP [sometimes] on a TV channel he part owns, delivering a party political broadcast on behalf of Reform UK? Seriously ... WTF?
Reform UK
@reformparty_ukSep 16
Nigel Farage exposes how Labour and the Tories hand out government contracts to their donors. Under Reform UK, contracts will benefit the taxpayer - not our donors.
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🆕NICE guidelines Arguably the biggest shift in #type2diabetes care in over a decade. Phenotype first. HbA1c second. @drkevinfernando & I are running a free hour on what it actually changes in clinic. Thu 10 Sept, 7-8pm BST No industry funding 🔗tickettailor.com/events/oran…
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GoggleDocs retweeted
Dr Amar Puttanna 🎸@AmarPutSep 4
Excited to work with @ATTDconf 👉🏽Management of older adults, technology & diabetes👈🏽 ❓How do we manage older adults with diabetes ❓How do we balance intervention with support and QOL ❓What is the role of technology & how can we simplify/facilitate us02web.zoom.us/webinar/regi…
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GoggleDocs retweeted
“CKD is not really a disease… trials don’t necessarily translate to living longer” Not really sure where to start here. But trials in the last 20 years in which CKD therapies extend survival: #DAPACKD HR 0.69 (0.53-0.88) #FIDELITY HR 0.89 (0.79-1.00) #FLOW HR 0.80 (0.67-0.95)
Replying to @mvaduganathan
lol. only talking about HF. TOPCAT in my view was positive trial due to fishiness in certain regions. SPIRITHF is harder to reconcile since stopped early. CKD is not really a disease and the outcomes from the trials don't necessarily translate to living better or longer. if you care so much about evidence why not advocate for a head to head trial? why are makers of finenrone and the academics who promote it afraid of elevating the best evidence?
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#Obesity care in the #NHS is an absolute and utter shambles Why don’t we just be honest and say we can’t afford any of the drugs till they go generic? Saves lot of people angst. And less said the better about improving conditions to tackle core issues of obesity Either needs new leadership or we need to park it in the “impossible” box and focus on other areas.
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Primary Care The bedrock of #NHS work And this is why I say that primary care leadership has failed within @NHSEngland in the decade or so NHSE has existed If you haven't been able to make the case for increased funding in THE area which does need that? I am afraid the outcomes follow the consequences of your inability to negotiate the funds. So- we are here- where we are. Leadership inactions or failures in a healthcare setting- always has consequences Perhaps never for the individual- yet always for the population. ( Data via @HealthFdn )
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🔥UK first in Europe to authorise #orforglipron for weight management & #T2D🔥 🎯Orforglipron is a small-molecule, non-peptide oral #GLP1RA See my @Medscape commentary piece on the ACHIEVE-1 trial from #ADA2025 for more background info - link in comments 👇🏾
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🔥Our @Medscape Primary Care #Hack on "Identification & Holistic Management of #CKD in Primary Care" has been updated for 2026! 🙏Thanks to my co-authors @EimearDarcy & Will Hinchliffe PDF download in comments 👇
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The national work in #Diabetes continues - as it must. To draw attention to: @NHSGIRFT report - Diabetes: Children & Young Adults #T1D #T2D Thank you @DrDita @SaimeFulya for the amazing work in ages 0-18 My area of interest ages 19-25 Relevance of transition services, tackling inequity, better or priority access - and a key group in BOTH types of #Diabetes - given the impact of a life long condition @NHSEngland @DHSCgovuk @pcdosociety @DiabetesUK @BT1DUK Read, share and use as appropriate gettingitrightfirsttime.co.u…
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September 2023. That’s when I started calling this all out re PAs And amidst all of this? The gall to accuse Gill Leng of bias- and then shut down by a legal court? Is something incredible. Threatening anyone who didn’t agree with their leaders views; Accusations of bias; Personal attacks; Referrals to GMC… Everything has been tried. And here we are. I may not know much about workforce - but I know that anyone in healthcare working outside their training? Will cause harm. Implement the Leng recommendations. Enough obfuscation done. @DHSCgovuk @NHSEngland @NHSE_WTE
A hot tip to those across Royal Colleges @AoMRC & @NHSE_WTE Ignoring issues about "Physician Associates" as "Just a social media thing" will cause huge issues going forwards A same approach has got us where we are with pay disputes We have a workforce crisis- do listen.
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GoggleDocs retweeted
Dr Amar Puttanna 🎸@AmarPutJun 23
Great to see NICE approval for Teplizumab! Know firsthand the hard work behind the scenes to get to this. A new era in T1D care 🙌🏽 Await the full NICE TA being available soon First drug to delay onset of type 1 diabetes made available on NHS bbc.com/news/articles/ce8mzd…
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