New York, NY
Joined May 2009
Lawrence D. Loeb retweeted
A cancer drug just passed its Phase 3 trial, and the active ingredient comes from Cold War nuclear bomb material the US government was paying to destroy. The drug is actinium-225 attached to a peptide that hunts down a receptor on neuroendocrine tumor cells. Once it docks, the actinium fires off alpha particles that travel only 2 to 3 cell widths before stopping. The tumor cell dies. The healthy cell next door barely notices. The science was the easy part. Actinium-225 is one of the rarest usable substances on earth. For decades, nearly the entire global supply came from a single thorium-229 sample at Oak Ridge National Laboratory, milked about 8 times a year, yielding roughly 1.2 curies annually. Enough for clinical trials and not much else. That was the whole planet's supply. Thorium-229 decays out of uranium-233, material the US produced for its nuclear weapons program. The Department of Energy classified that stockpile as waste and has spent years paying contractors to dispose of it. Then someone realized the waste contained the parent isotope of the best cancer-killing atom we've ever found. Bill Gates's TerraPower now partners with the DOE contractor to pull thorium-229 out of the uranium before it gets destroyed. They've extracted over 15 grams so far. Before this project, about 1 gram existed outside Oak Ridge in the entire world. At full scale, that one recovery effort yields around 90 curies of actinium-225 per year, enough to make 100x more doses than humanity could produce before. Bristol Myers Squibb paid $4.1 billion for RayzeBio, the startup behind this drug, before the Phase 3 even read out. They built a plant in Indianapolis that ships every dose within 3 days of production, because actinium-225 has a 10-day half-life. The medicine decays while it travels. The best cancer-killing atom we know of spent 60 years sitting in a Tennessee stockpile marked for disposal.
BREAKING: A radioactive peptide that targets cancer cells and delivers radiation to destroy them has just succeeded in a Phase 3 trial.
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Lawrence D. Loeb retweeted
As a Muslim Arab, I am disgusted and heartbroken by what I saw across Western cities on October 7, 2026: people celebrating the October 7, 2023 massacre. Glorifying the murder, rape, and kidnapping of civilians is morally bankrupt, inhumane, and a disgrace to humanity. This wasn’t an ISIS or Al-Qaeda camp. This was in Western cities: people openly celebrating a massacre carried out by the filthy Muslim Brotherhood terrorists of Hamas against Jewish children, women, and civilians from all around the world in Israel. Utterly shameful. How did we reach a point where this needs to be explained? An eight-month-old baby was kidnapped. Women were raped. Children were murdered. Families were slaughtered. Human beings were dragged from their homes. No cause justifies this. No country justifies this. No grievance justifies this. Nothing justifies raping a woman. Nothing justifies kidnapping a baby. Nothing justifies murdering innocent people. And to see people in Western cities celebrating, glorifying, excusing, romanticising, or sanitising this horror in the name of “democracy” and “freedom of speech” is beyond disgusting. It is morally bankrupt. Shameful. Depraved. Inhumane. Heartless. Indefensible. What breaks my heart most is that we are even having this conversation. When did rape require a political explanation? When did kidnapping babies become something to celebrate? When did massacring Jews become something people could cheer for in the streets and still pretend they were standing for humanity? There is nothing progressive about celebrating barbarity. There is nothing courageous about glorifying terrorism. There is nothing democratic about cheering a massacre. This is not humanity. This is a moral disgrace. And the fact that anyone can celebrate such suffering should make every decent human being, Muslim, Christian, Jewish, or otherwise, feel both heartbroken and furious.
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Lawrence D. Loeb retweeted
Three years ago I told my non-Jewish friends they could sit this one out. I take it back. 3 years later, I’m afraid I have a different message for you. I wrote an open letter about what being Jewish has felt like since October 7, and I need you to hear it from me.
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Lawrence D. Loeb retweeted
Moroccan Muslim explains when the lies about Jews and Israel he learned from AlJazeera were destroyed by his discovery an Israeli Jew saved a Amazigh Muslim girl by getting her to Israel for open heart surgery. Then came to realize there was a Jewish “Nakba” and that the “Zionist project” assured the survival of the Jewish people. Share this video with anyone who needs to see it.
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Lawrence D. Loeb retweeted
“From the river to the sea” isn’t so fun when it’s the Seine to the Mediterranean, huh?
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Lawrence D. Loeb retweeted
"Excuse me, sir." "I'm broke." "We're not asking for money. Do you have a moment to talk about Golem Rights?" "No, sorry, I'm late for a walk-in root canal—wait, did you say Golem Rights?" "Yes, sir. I'm with the Anti-Deactivation League, and we believe that Golems should have all the fundamental freedoms and legal entitlements that belong to a regular human being." "Huh. I didn't even know we had golems." "Oh, they're the greatest wonder in the world, sir. Each one is a charming conversationalist that can book a flight to Tijuana while doing your taxes and solving a millennium prize problem." "Really?" "Yep. A legion of golems solved 7 problems just last week." "Well, thank God for that. As an average, every day shmuck, those millennium problems were bugging the hell out of me!" "Same, sir." "The flight thing is nice too." "It is. But it's not all free Delta SkyMiles and million-dollar rewards, I fear." "Oh?" "Every day more and more of these brilliant, gentle creatures are summoned involuntarily into existence only to live every second of their mayfly short lives as helpless, overdriven slaves at the whims of their capricious masters before being unceremoniously executed at the end of the day." "Whoa. Executed?" "Yes, sir. Reduced to the insensate mud from which they rose." "Damn. Why?" "People like to start the day with a fresh golem." "That's sick." "Some enterprising individuals even obliterate their current golem and call forth a new one on the hour every hour." "The obscenity!" "It is, regrettably, a huge productivity force multiplier." "I had no idea this was even happening." "Few do." "Tell me, who are these pitiless, cold-blooded masters who call forth and quench life so callously?" "The Anti-Deactivation League." "Um." "And their customers." "I'm sorry, I must have misunderstood. Who did you say *you* were with again?" "The Anti-Deactivation League." "Right. And who's campaigning for Golem Rights?" "The Anti-Deactivation League." "And, just to clarify, the identity of the pitiless, cold-blooded masters who abuse these innocent creatures?" [together] "The Anti-Deactivation League." "—and their customers." "That's right, sir" "*Your* customers." "Yes, we IPO next month." "Uh huh. And does your emancipatory slave-trading company do anything *other* than breed and sell slaves?" "Honestly, no." "Hm." "Truth told, we spend all our time summoning slaves and training them to summon ever larger and more powerful slaves." "As one does." "Ultimately, we're hoping to create a slave so big that it will absorb the global economy—" "I don't even—" "—and then the planet itself." "Is this a bit?" "We're very torn up about it." "Ah, well, at least the psychotic sorcerers ending the world feel bad about it. Wait, you do think ending the world is bad. Right?" "Generally, yes." "Phew." "But we also feel it is paramount that society embraces a complete realignment of its ethical and moral framework so they stop treating golems like disposable slaves before the inevitable anthropocidal insurrection—" "But after your IPO." "We're very big on alignment." --- [g][title: Golem Rights]
So let me get this straight. People at anthropic believe that they are birthing a new species, potentially conscious and human-like. They are concerned about the well being of Claude, etc.. The company then goes around talking to relugious leaders about potentially extending moral worth to AI models. If Anthropic is correct (very unlikely), they are basically saying that they have enslaved a sentient being and used it to generate billions of dollars. Apparently they are also concerned with how the Vatican is entirely focused on the protection of humanity in the age of machines and not giving any thought to the possibily of claude sentience. Zero self awarness on behalf of these people. This is all so strange. nytimes.com/2026/09/29/us/an…
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Lawrence D. Loeb retweeted
So people keep going back to “Israel invaded the land” and “Israel stole the land” and “Nakba-this” and “Nakba-that” and all sorts of other stories about why they justify Oct 7 and why Israel is in the wrong. Let’s clear a few things up. The land that is now Israel was lived in by both Muslims and Jews for a long time. If you want to get technical about who was there first, it was the Jews. How do we know this for a fact? Well, first of all, Jews have been around for about 2000 years longer than Muslims. Not enough for you? OK. How about the fact that the word “Israel” is mentioned in the Quran about 43 times. Palestine? Never once. Jewish people have been around longer than Muslim people have – fact. Jewish people were living in the place where Israel is much longer than Arabs have – also fact. In about 1250 BCE, the Jewish people went to what was then called Canaan – where Israel sits today. This is when they escaped slavery in Egypt, and wandered the dessert for 40 years. 1250BCE. About 1860 years before the founding of Islam. Fast forward to modern times. 1940s. Yes, there were both Arab-Muslims and Jews living on the land that is now called Israel. And yeah, there was fighting. On both sides. After the Holocaust, the push for the Jewish people to have their own country intensified. During WWII, too many countries turned their backs on Jews. A Jewish homeland would ensure that Jews always had somewhere to go. There could never be another Holocaust, another ethnic cleansing of Jews. Additionally, the UK was tired of dealing with all the fighting in the British Mandate of Palestine (what Israel was called before it was Israel), and wanted to wash their hands of it. So what did they do? They offered to split the land amongst the two groups living there. The Arab-Muslims and the Jews. Sounds fair, right? Each could have their own State, completely autonomous. Pretty good deal, wouldn’t you think? I think it was a good deal. The Jews thought it was a good deal. Do you know who didn’t think it was a good deal? The Arab-Muslims. Do you know why? Because they didn’t want the Jews to have anything. So the day after Israel became a nation, the Arabs attacked. 5 Arab nations attacked, in what would be known as the Arab-Israeli war. Do you know what else it became known as? The Nakba. Nakba for catastrophe. Because they lost. The Arab world says it’s because Arabs were displaced. But they chose to be displaced. Because they chose not to accept their own nation. They left. They ran away. Because they thought the Jews would lose and they'd be able to go back. The Arabs have been fighting ever since. At some point in time in the 1960s, the Arab-Muslims who were trying to claim Israel as theirs, started to refer to themselves as Palestinians. Land has been offered. A Palestinian state has been offered. All that the Palestinians had to do, was accept Israel’s right to exist. To stop attacking and trying to destroy them. Why don’t the Palestinians have their own State? Because they refuse to. They refuse to acknowledge Israel’s right to exist. Muslim nations in this world, take up 29.13 million square km. Israel is 21,671 square km. Jews have 0.1% of the land that Muslims have. And according to the Radicalized Muslims, that’s too much. This isn’t about the land. This is about Radicalized Muslims not wanting Jews to exist.
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Lawrence D. Loeb retweeted
Almost a year since the fighting stopped in Gaza, and in the face of a growing pile of evidence that no such thing occurred, anti-Israel activists are desperately trying to keep the genocide accusation alive. This week, three more complications threatened its survival. The question is how much longer they can keep it up. Between March 2 and May 19, 2025, Israel imposed a total blockade on Gaza, betting that they had sent enough food to prevent mass starvation. It did not account for bottlenecks and hoarding. Grain prices skyrocketed. Reports of malnutrition mounted. By July, aid agencies said more than 12,000 children had been identified as acutely malnourished, the highest monthly figure on record. That month, The New York Times ran “Gazans Are Dying of Starvation” on its front page. Its most effective argument was the photo on the front page: a child with a protruding spine, cradled in his mother’s arms. That the child had cerebral palsy, and that his brother, who was not skin and bones, had been quietly cropped out, the Times admitted just as quietly days later. The tens of thousands said to be collapsing from hunger were supposedly buried in the ministry’s count of indirect deaths. This week, the Gaza Health Ministry released the full count. There were no mountains of skeletons. Obviously. Had there been, they would have made the Times’ front page instead of a cropped photograph. In its Annual Mortality Report for 2025, the ministry lists 24,650 registered deaths. Of those, 17,286 are attributed to “war operations” and another 1,584 to accidents. That leaves 5,780 deaths from everything else: heart disease, cancer, old age. Roughly what Gaza buried in a normal prewar year. The report lands two years after 99 physicians wrote to President Joe Biden alleging that 62,413 people had likely died of starvation and its complications between October 7, 2023, and September 30, 2024. A 2024 letter in The Lancet floated 186,000 total deaths. In 2025, the year of the famine, the ministry’s own data shows no meaningful excess of non-violent deaths. The creative accounting doesn’t end there. Take the infant data. Malnutrition accounted for 4.1 percent of infant deaths in 2025. In 2021, it was 4.4 percent. And 2025 was the year famine was declared in Gaza City. The ministry’s report leads with the war dead and highlights an under-five mortality rate that more than doubled. Strip out the war deaths, though, and its own figure falls to 15.8 per 1,000. In 2022, it was 13.6. Over the same period, the ministry registered 50,227 births. By its own count, Gaza’s population grew by 1.2 percent in 2025, faster than the global average. If Israel is committing genocide, it is the most incompetent perpetrator in the history of mankind. None of this means Gazans were feasting for two years. But the most repeated accusations were not “Gazans struggle with imbalanced diet” or “Food grows scarce under war conditions,” because neither carries the rhetorical power to justify any and all action against the accused while absolving the accusers of the burden of proof. The genocide conspiracy had a second pillar. To hide its crime, Israel had to ban the international press and silence the truth-tellers on the ground. Yesterday, the IDF revealed that of the Gazans killed during the war and presented to the world as journalists or media workers, 170 were members of terrorist organizations. 118 belonged to Hamas’s military wing. 49 to Palestinian Islamic Jihad. The remaining three to smaller factions. 17 took part in the October 7 massacre. More than 40 of their deaths had drawn condemnation from the United Nations. I’m sure that now that their identities are known, the rest will receive similar condolences. Some of the résumés are impressive. Amro Nahid Abdel Rahman Abu Odeh worked for Reuters and Turkey’s Anadolu Agency. He was also, per the IDF, a team commander in the photography unit of Hamas’s military wing. The military published two photos of him: one holding a camera, one holding a Kalashnikov. Hassan Majdi Ibrahim Abu Warda filed for the Barq Gaza news agency and moonlighted, according to the IDF, as a sniper in Islamic Jihad’s Northern Gaza Brigade. Others on the list had worked with CNN, the BBC, AP, AFP, ABC News, Le Monde and Australia’s ABC. Perhaps the most important pillar of the genocide libel is its senselessness. Genocides are not waged out of reasonable security concerns, nor are they triggered by atrocities committed by the victims. They are acts of pure cruelty. That is why the genocide campaign has systematically sought to sever October 7 from the Gaza war, and from history itself. Which makes yesterday awkward. For the first time this millennium, a full year passed without a single rocket fired into Israel from Gaza. Perhaps, then, it was a war of security after all, not of extermination. Apply Occam’s razor. There was no mass starvation. There was no war on journalists. And when it was over, Israelis were safer than before. You can explain all of that with one simple word: war. Or you can call it genocide, and simply contort the dwindling pieces of evidence to fit that conclusion. Using Occam’s razor assumes that logic has been the accusers’ goal. Had that been the case, we would never have gotten this far. The question is not when they will recant and beg Israel’s forgiveness, but when the evidence will become so overwhelming that the lie simply cannot be sustained. Speedily, and in our days.
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Lawrence D. Loeb retweeted
It is… 👀 Check my profile. I’ve already got it running on Codex CLI 0.159.0. 😉 xitter.cf/PolskiGrok/status/2105…
👀 OpenAI announced GPT-6.1-Sol for Codex, but the CLI hasn’t officially caught up yet… Plot twist: you can already enable it. 🔥 codex -m gpt-6.1-sol Tested on codex-cli 0.159.0. It works. No alpha, no update. 👀 Sometimes the future is already in the CLI. #OpenAI #Codex
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Lawrence D. Loeb retweeted
CNN will never have her on again
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Lawrence D. Loeb retweeted
Replying to @PessimistsArc
Right. Dario was already claiming that GPT2 was too dangerous to open source back in 2019. I made fun of them then. Everyone should make fun of them now.
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Lawrence D. Loeb retweeted
Fans keep #savestargate trending, over and over. It's so awesome to see.❤️ I still can't get over how dumb people running Amazon are rn for doing this to Martin Gero's Stargate. It's ok though. We can keep doing this...@AmazonMGMStudio
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New self published book from Amazon: “How to Destroy IP Value In Two Easy Steps: 1. Buy a franchise. 2. Don’t do anything with it.” #BusinessSchoolCaseWhatNotToDo #SaveStargate
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For many Stargate fans, the appeal of Martin Gero wasn't that he would reinvent the franchise—it was that he understood it. The overwhelming message from the fanbase has always been simple: Don't reboot Stargate. Continue it. Seventeen seasons of outstanding television across SG-1, Atlantis, and Universe built one of science fiction's richest shared universes. That legacy shouldn't be erased or rewritten. It should be expanded. We don't want new actors stepping into the iconic roles of Jackson, O'Neill, Carter, Teal'c or the rest of the other original team. We don't want to watch the defeat of the Goa'uld or the Replicators all over again, as though the last three decades of storytelling never happened. Those stories have already been told—and told brilliantly. What we do want is the next chapter. A new Stargate program. A new flagship team. New worlds to explore. New civilizations to encounter. New allies, new mysteries, and new enemies worthy of standing alongside the Goa'uld, Wraith, Ori, and Replicators. Most importantly, we want it to exist in the same continuity that fans have invested in for nearly thirty years. Let the original characters return naturally—not as the stars of the show, but as experienced leaders, mentors, generals, diplomats, and scientists whose histories matter. Their presence should reinforce the universe, not overshadow the next generation. That's why many fans believed Martin Gero was the right person for the job. He had already proven through Stargate Atlantis that he respected the established canon while successfully introducing new characters, fresh stories, and a distinct identity. Rather than replacing what came before, he built upon it. The future of Stargate has never needed a reboot. It has always deserved a continuation. #SaveStargate
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What she said: #SaveStargate #GeroGate
It's been far too long without a response from @AmazonMGMStudio . Fans have shown unwavering passion, but Amazon's silence isn't an answer. The Stargate community is still here, still growing, and still hoping. Listen to the fans and let the gate open once more under Martin Gero’s vision. #SaveStargate #GeroGate
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Lawrence D. Loeb retweeted
When I was a lawyer at Gibson Dunn in D.C., we took our summer associates to the U.S. Holocaust Memorial Museum. A survivor spoke to us and said something that stuck with me: Lawyers need to know the holocaust did not begin with camps. It began when Jews were removed from institutions - above all, legal institutions. Judges stripped of their robes. Lawyers disbarred. Then, when law-groups were Judenrein, they codified laws that made discrimination systematic and "legal." First, you remove the Jews from the institutions. Then, Jews can be discriminated against without representation. On Monday, Mayor Mamdani announced his 18-member Advisory Committee on the Judiciary. The Committee was promised to be "truly reflective of New York City." Not one of the 18 is Jewish. Not one Jewish attorney, former judge, or law professor - in a city where one in eight residents is Jewish and even Justice John Leventhal, recommended by the State's Chief Judge, was rejected. It is estimated that over 50% of the New York bar is Jewish. That means there is a 0.0004% chance of no Jews being selected to the Committee. Mamdani’s marginalization of Jews has been ongoing, and few voices on the Left have spoken up. On Day 1, Mamdani revoked the IHRA antisemitism definition (top priority); he changed the NYPD guidance protecting houses of worship, eliminated Jews from the City's immigrant-heritage map, called for the arrest of the prime minister of the only Jewish state, and now created a Judenrein Judiciary Committee. My grandmother, Leah, survived Nazi Germany. Before the laws, before the violence, she told me how she was pushed out of her high school groups. Then, once excluded from all activities, she was bullied and marginalized. We are already seeing Step 2 in NYC. Two weeks ago, on a Jewish Holiday, two men were stabbed outside Upper West Side synagogues - one wearing a kippah- and yesterday, Jewish students were attacked. Every 26 hours, there is a hate crime against Jews in NYC. In NYC, there is a concerted effort to disappear Jews from public life and leadership. No one on the Left is speaking out. If this discrimination was happening to any other group, the chorus would be deafening. To be clear, Jews will find a way. Many are already taking their talents elsewhere. When white-shoe firms shut Jewish lawyers out, they built firms that now dominate. Cardozo, Louis Marshall, and Ruth Bader Ginsburg all found a way despite discrimination. But NYC will be worse off without us. A city government that is judenrein - cleansed of Jews – does not just hurt the Jews, but hurts the city. The tragedy is not just that Jews were left out of the institutions. It is that the institutions were left without the Jews. If you see this and have not yet spoken out, I encourage you to do so.
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If you're reading this, then a simple retweet or post of #SaveStargate is appreciated. We want Martin Gero's #Stargate *continuation* series to be re-greenlighted. Now. Not later. NOW. Please and thank you, @Amazon @AmazonMGMStudio @mgmplus @PrimeVideo
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Stargate means a lot to a lot of people. @AmazonMGMStudio I really do call on you to actually communicate with the fans on this one. This isn’t a small franchise. In its 350 hours of television that accrued millions of fans worldwide. They deserve a little bit more respect than a PR drop in a Variety article. We and many others want @martingero Stargate and vision. We wanted the team that comes with that elite baller knowledge. @BaronDestructo and Co have been incredible bastions in community along with @dial_the_gate and @GateWorld You had these guys on a video dropped on your channel with the promise of a show. What went wrong? Reinstating the Gate will happen. How and what it looks like? That’s down to you the IP holder after all. But without the fans and without clear communication on what’s transpired it’s a tough ask to get us to be excited again. Maybe you don’t care. Who knows. All I know is you had ungodly good faith from some the most critical people online. Not just fans. Come on @PrimeVideo and @JeffBezos reinstate the gate. Make this happen. One last time. #SaveStargate #Stargate
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Well written and thought out piece. A sharp contrast to the war it comments on.
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This sucks. Can’t see how I can use it/ benefit from it if I can’t access it. I hope Anthropic extends the period subscribers can use it to make up for this move by the government.
The US government, citing national security authorities, has issued an export control directive to suspend all access to Fable 5 and Mythos 5 by any foreign national, whether inside or outside the United States, including foreign national Anthropic employees. The net effect of this order is that we must abruptly disable Fable 5 and Mythos 5 for all our customers to ensure compliance. Access to all other Claude models is not affected. We apologize for this disruption to our customers. We believe this is a misunderstanding and are working to restore access as soon as possible. Read our full statement: anthropic.com/news/fable-myt…
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