Luca Del Prete MD retweeted
Does portal vein stenosis threaten long-term survival after pediatric LT?
🌍 In 239 patients from 21 centers, 10-year graft and patient survival were 90% and 96%. PVS diagnosed ≤7 days after LT showed the poorest 1-year outcomes.
doi.org/10.1097/LVT.00000000…
#LiverX #LiverFellows
Luca Del Prete MD retweeted
For benign and low-grade #PancreaticHead tumors, enucleation was associated with more clinically relevant postoperative pancreatic fistula vs pancreatoduodenectomy, but fewer major complications and shorter hospitalization.
ja.ma/4ANKT2r
Luca Del Prete MD retweeted
#PediatricLT is more than the operation 👶
Recent AASLD/AST/NASPGHAN guidance covers vascular complications, #immunosuppression toxicity, infection prevention, #nutrition, development and transition to adult care.
A roadmap for life after pediatric LT.
doi.org/10.1097/LVT.00000000…
Luca Del Prete MD retweeted
#PostoperativeHypertension should be treated only when symptomatic. As-needed medications for asymptomatic hypertension increase risk of adverse outcomes, supporting a conservative management approach. ja.ma/4gC1Ao3
Luca Del Prete MD retweeted
Low sodium, high stakes 🧂⚠️
Why does hyponatremia occur in cirrhosis, how should it be evaluated, and when does treatment become urgent?
Check out this #LFN Back to Basics review on hyponatremia in cirrhosis!
Author: Dr. Victoria Kusztos ✍️
🔗: aasld.org/liver-fellow-netwo…
Luca Del Prete MD retweeted
Ascites is not one phenotype. In LT candidates, 3 reproducible phenotypes emerged. Vasodilatory-synthetic dysfunction carried ~3-fold higher AKI risk despite MELD 3.0 adjustment, but no higher waitlist mortality.
#LiverTwitter #Ascites #Transplantation
doi.org/10.1097/LVT.00000000…
Luca Del Prete MD retweeted
Overcoming hepatic artery variations: Arterial reconstruction strategies to expand normothermic machine perfusion in liver transplantation
journals.lww.com/lt/abstract…
Luca Del Prete MD retweeted
Risk factors of biliary cast syndrome among liver transplant recipients
journals.lww.com/lt/abstract…
Luca Del Prete MD retweeted
Overcoming hepatic artery variations: Arterial reconstruction strategies to expand normothermic machine perfusion in liver transplantation
journals.lww.com/lt/abstract…
Luca Del Prete MD retweeted
A simple intraoperative score incorporating thromboelastometric parameters predicts early reoperation for bleeding after liver transplantation
journals.lww.com/lt/abstract…
Luca Del Prete MD retweeted
Liver transplantation indications and strategies in polycystic liver disease: A European survey
journals.lww.com/lt/fulltext…
Luca Del Prete MD retweeted
A new global milestone in transplantation has been reached: A total of 173,727 solid organ transplants were performed worldwide in 2024, which is the highest number ever recorded and represents a 2% increase on 2023.
Download this freely available paper! tinyurl.com/z9842fd9
Luca Del Prete MD retweeted
🎉 Our brilliant new #SurgOnc clinical fellows have already been at work for a month!
Welcome to Toronto and the program @aleborghiMD 🇮🇹 @DrShellyLuu 🇨🇦 @julielaMD 🇨🇦 & Alberto Riojas 🇲🇽🌟
Luca Del Prete MD retweeted
Major step forward toward cure for diabetes in trial led by Dr Trevor Reichman, Director of Pancreas & Islet Transplant Program @UHNTransplant @UHN_Surgery @UHN_Research @UHN nejm.org/doi/full/10.1056/NE…
Luca Del Prete MD retweeted
🧒🩺 New from Drs. @AmandaJensenMD & Carlos Esquivel in @LTxJournal: In pediatric liver transplants, choledochoduodenostomy (CD) had the fewest biliary complications—lower stricture & leak rates than traditional options. CD is safe & may be superior.
🔗: tinyurl.com/efe6u6wc?sf22695…
Luca Del Prete MD retweeted
IPMN 🍇 without HRS and long term risk of cancer development
🇯🇵 2.5k pts > 5 years surveillance
🫧 IPMN size and growth predict cancer within 5 years
🤏 MPD diameter at 5 years predicts cancer after 5 years
gut.bmj.com/content/74/6/971
Luca Del Prete MD retweeted
Pancreatic cancer, often linked to smoking, obesity and diabetes, is predicted to become the 2nd leading cause of cancer-related death by 2030.
A recent Seminar discusses the need for novel therapies & future directions for research: hubs.li/Q03hN4Hj0
Luca Del Prete MD retweeted
Deceased donor liver utilisation & assessment, consensus guidelines from ELITA including practical considerations/recommendations on:
🚧 adverse outcomes to be used to define suitability for #transplantation with conventional SCS alone
⚖️ donor & graft factors to define liver suitability for #Tx after SCS for DBD or SRR & conventional SCS for DCD
⚖️ intended recipient & suitability for #tranplantation
🩸in situ normothermic regional perfusion
🌡️❄️ex situ hypo/normothermic machine perfusion
🩸perfusion strategy for DBD & DCD livers
⚙️ combining perfusion vs isolated strategies
📏parameters to be measured during NRP, NMP, HOPE & combined modalities for livers assessment
🔍assessment of hepatocytes & biliary tree during perfusion
@ESOTtransplant @gabriel_oniscu @CFondevila @hessheimer
🖇️ bit.ly/3Yg1074
Luca Del Prete MD retweeted
Normothermic regional perfusion (NRP) boosts organ recovery, but ethical concerns slow adoption. A scoping freely downloadable review explores key debates on donor harm, consent, trust, & justice. Can ethical challenges be resolved? #TXPforAll #OpenAccess tinyurl.com/mr2883wy
Luca Del Prete MD retweeted
Update on Portopulmonary hypertension guideline by International liver transplantation society
📌Hemodynamic definitions
📌Management approaches
📌POPH MELD exception criteria
📌Long-term outcomes
#livertwitter
journals.lww.com/lt/abstract…
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@HowardTLeeMD
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