The Department of Revenue, Ministry of Finance, Government of India, vide Notification S.O. 1259(E) dated 11.03.2026, has notified 2-Bromo-4-Methylpropiophenone (CAS No. 1451-82-7) as a controlled substance under the Narcotic Drugs and Psychotropic Substances (Regulation of Controlled Substances) Order, 2013, due to its increasing use in manufacturer of mephedrone (4-methylmethcathinone), a psychotropic substance. All persons and entities engaged in the manufacture, distribution, sale, purchase, possession, storage, consumption, import or export or in offering 2-Bromo-4-Methylpropiophenone for sale or distribution, or in mediating its sale or purchase, including through any website, social media platform or other electronic means, are required to obtain registration number in Form A from the jurisdictional Zonal Director, Narcotics Control Bureau, in accordance with the NDPS (RCS) Order, 2013. All such firms/entities are requested to submit registration applications in Form B to the concerned NCB Zonal Unit well in advance, i.e., on or before Aug 7, 2026, so that the registration number is issued by NCB within the statutory period of 180 days from March 11, 2026: Narcotics Control Bureau