Radiation Oncologist at Mass General Brigham Cancer Institute, Brigham and Womenβs Hospital, Harvard Medical School. Views are my own.
Joined October 2018
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Mutlay Sayan, MD retweeted
Post-prostatectomy RT in just 5 fractions? π
Ferrario et al and POPART team reports 100 pts treated with prostate-bed SBRT (32.5 Gy/5 fx):
β’ Late β₯G2 GU toxicity: 8.5%
β’ Only 1 late G2 GI event
β’ Just 3 in-field relapses
β’ 30-mo biochemical control: 74%
Very encouraging local control and toxicityβbut urinary QoL remains important to watch.
#ASTRO26 #ProstateCancer #SBRT @HimanshuNagarMD @rtdess @RadOncDocJ @angela_jia_ @urotoday @TylerSbrt
Mutlay Sayan, MD retweeted
Not to mention, no disease control benefit to dose escalation. @DrSpratticus @angela_jia_ @MoningiShalini @MutlaySayan
Mutlay Sayan, MD retweeted
Reinforces the signal from NRG-GU006/BALANCE presented last year by @DrSpratticus and legacy of @felixfengmd β A step toward more personalized post-op secondary RT
Mutlay Sayan, MD retweeted
New #ASTRO2026 data from @NRGOnc /RTOG 0534 SPPORT π¬π§¬ presented by Shuang (George) Zhao @UTMDAnderson. PAM50 Luminal B = both prognostic & predictive of benefit from postop ADT.
π 5-y FFP benefit: 31% vs 10% (p-int=.01)
π― 10-y MFS: 20% vs -3% (p-int=.05)
#Pcsm @Astro_org
Mutlay Sayan, MD retweeted
Posthoc analysis of RTOG 0534 independently validates NRG-GU006: PAM50 LumB predicts hormone benefit after prostatectomy (FFP +31% in lumB vs +10% non-LumB, P-int=.01; MFS +20% vs β3%, P-int=.05).
PAM50 should be SOC and has higher level evidence than Oncotype for breast cancer!
#ASTRO26 @urotoday @Decipher_VCYT @AmarUKishan @DrChoueiri @angela_jia_ @jamesbyu @HimanshuNagarMD @TylerSbrt @SbrtSean @MutlaySayan
Mutlay Sayan, MD retweeted
#astro26 @SiemensHealth
The first 7 sites in the world and honored to be part of this esteemed group from MGB, MSKCC, Mayo, and Wash U, and of course UH Seidman Cancer Center!
#ASTRO26
Accela and the neo. Proud for @RadOncUH to be the first center in the world to enroll a patient on a trial with this amazing tech.
@DrAndrewLoblaw @alison_tree @ASTRO_org @AmarUKishan @cwspeers @DrewMoghanaki @freddyeescorcia @EvanThomas84 @EricTopol @montypal @neerajaiims @wandering_gu @PGrivasMDPhD @shilpaonc @TylerSbrt @DrChoueiri @piet_ost @sueyom @jamesbyu @NehaVapiwala @NRGonc @nytimes @washingtonpost @EricTopol @urotoday @SbrtSean
Mutlay Sayan, MD retweeted
The faculty lineup for #WorldGU26 continues to grow! Several more outstanding thought leaders have joined since our last announcement, and thereβs still more to come. Check out the updated faculty roster, featuring conference chairs @CaPsurvivorship & @Daniel_J_George ow.ly/vvfG50YMUgU
The 2-day CE-accredited conference returns to Nashville, TN, on December 3-5, 2026. Save the date and follow us for more faculty announcements and updates!
Who are you most excited to hear from?
@aaparicioMD @tingbao2011 @PBarataMD @katy_beckermann @mishabeltran @jackiebrown_MD @AlanBryce9 @drjefstathiou @MarkTFlemingMD1 @BGarmezy @OncHahn @MRHarrisonMD @EHeath4100 @EJonasch @MonikaJoshimd @jonathan_leeman @PavlosMsaouel @maughanonc @BradMcG04 @CParkMD @drphil_urology @EdwinPosadasMD @charlesryanmd @MutlaySayan @Scarps_kristen @cnsternberg @sonpavde @sandysrimd @alantanmd @DrKarineTawagi @drulkav @jeffyoriomd @bilenma @TDorffOnc @NaomiHaas5 @MikeLattanzi @MoningiShalini @ashleyrossmdphd @bsomer @HHammersMD @MattMilowsky
Mutlay Sayan, MD retweeted
Highlights from the Christopher G. Wood Urologic Oncology Symposium - Tian Zhang
@Daniel_J_George @utswcancer @CChuMD @hannahdzmd @CharlesJiangMD @daniel_igel @MutlaySayan @doctorjakeuro @Dr_RaviMadan @ChapinMD @DocMattCampbell @ndesai2005 @UroCancer @UTMDAnderson @NRGonc @SWOG @MutlaySayan @ChadTangMD @CharlesJiangMD
oncodaily.com/voices/tian-zhβ¦
#OncoDaily #Oncology #Cancer #Health #Medicine #MedX #MedTwitter #ChrisWood26
Mutlay Sayan, MD retweeted
Faculty Update! π£ Additional thought leaders have joined the faculty lineup for #WorldGU26! The roster is live on our website, featuring our conference chairs @CaPsurvivorship
& @Daniel_J_George and 80+ national experts in genitourinary oncology: ow.ly/ypzK50YzYcl
The 2-day CE-accredited conference will be back in Nashville, TN, on December 3-5, 2026. Save the date and stay tuned for registration launching soon!
Who are you most excited to hear from?
@aaparicioMD @tingbao2011 @PBarataMD @katy_beckermann @mishabeltran @jackiebrown_MD @AlanBryce9 @drjefstathiou @MarkTFlemingMD1 @BGarmezy @OncHahn @MRHarrisonMD @EHeath4100 @EJonasch @MonikaJoshimd @jonathan_leeman @PavlosMsaouel @maughanonc @BradMcG04 @CParkMD @drphil_urology @EdwinPosadasMD @charlesryanmd @MutlaySayan @Scarps_kristen @cnsternberg @sonpavde @sandysrimd @alantanmd @DrKarineTawagi @drulkav @jeffyoriomd @bilenma @TDorffOnc @NaomiHaas5 @MikeLattanzi @MoningiShalini @ashleyrossmdphd @bsomer
Mutlay Sayan, MD retweeted
Had an absolute blast hosting the inimitable @DrPaulNguyen at @RadOncTMC.
World-class mind, zero airs π
Residents brought their A-game with their presentations.
Inspiring, energizing, charming and a whole lot of fun.
Had our residents thinking, and smiling. π
Brilliant!
Mutlay Sayan, MD retweeted
Join us in celebrating our 2026 Award Recipients. π
Gold Medalists:
@hedvighricak
@DrDMonticciolo
Honorary Fellows:
@banu_atalar
@Kriklund
Bien Soo Tan, MD
We look forward to recognizing these honorees during #ACR2026. Learn more: bit.ly/4ohTfIg
ALT Gold merit medal from the American College of Radiology with a blue and white ribbon, lying on a grey fabric.
Mutlay Sayan, MD retweeted
This year's @ASTRO_org is a big meeting for GU trials and science! I'm looking forward to hearing the results of many important GU trials such as:
π¬ Monday's 1:30 Plenary session - NRG GU005, BART
π¬ Sunday's 1:00 Clinical trials session - LUNAR, NRG GU006, NRG/RTOG 0924
π¬ Plus all of the Educational and Science sessions!
What are you looking forward to most this year?
@RonaldChenMD @jmmrad @DrHowardSandler @SameerKeoleMD @NehaVapiwala @Doug_Radonc @ChelseaPinnix @DrChrisCorso @CurtilandD @DrMalikaSiker @catherynyashar @IBCradiation @A_CT_SimMDJD @ZacharyBWhiteII @EmilyHollis @Ggreen1986 @MorganSLevy @Hysr_Ly @NataliyaMedPhys @MustafaBasree @RadOncDoc_Niema @TheMedNet @l_ballas @VedangMurthy @DrSpratticus @vedangmurthy @AmarUKishan @NRGonc @DrPaulNguyen
#ASTRO25 #RadiationOncology #CancerResearch
Mutlay Sayan, MD retweeted
π Celebrating #WorldGU25
Honored to take the stage at the World Conference on Genitourinary Cancers recently in Nashville! It was an incredible setting at the Country Music Hall of Fame and Museum and a privilege to contribute alongside so many leaders in the field. A highlight for me was hearing Olympian high jumper ChauntΓ© Lowe share her inspiring story of beating cancer, a reminder of the resilience and dedication that drives us all.
Big congratulations to Alicia Morgans, M.D., MPH and Dan George, M.D. and the entire IDEOlogy Health team for hosting such a successful meeting. And thanks to the dynamic Mark Pomerantz for hosting GU Pardy and congratulations to Team Bladder who won the World GU-Pardy finale, securing a $2,500 donation to BCAN in support of bladder cancer research and advocacy!
The program was highly educational and insightful. It was the perfect balance of learning, collaboration, fun, and community. I'm already looking forward to next year!
#WorldGU25 #Oncology #CancerResearch #MedicalEducation #Urology #OncologyCommunity
@countrymusichof @cchauntelowe @CaPsurvivorship @Daniel_J_George @michaelabern @DanBarocas @katy_beckermann @bergsa83 @bilenma @BraunMDPhD @UroCancerMD @jackiebrown_MD @mkbupathi @DrCaliff_FDA @DrDarrenFeldman @MarkTFlemingMD1 @Bgarmezy @RajanTGuptaMD @HHammersMD @MRHarrisonMD @EHeath4100 @KHoffmanMD @HJacene @EJonasch @MonikaJoshimd @MikeLattanzi @jonathan_leeman @LoebStacy @Dr_RaviMadan @maughanonc @MattMilowsky @CParkMD @DrJohnGPhillip1 @drphil_urology @ERPlimackMD @EdwinPosadasMD @brian_rini @ashleyrossmdphd @MutlaySayan @MikeSchweizerMD @KidneyCancerDoc @bsomer @DrVaishampayan @jeffyoriomd @Alantanmd @DrKarineTawagi @charlesryanmd @IDEOlogyHealth @oncodaily @BladderCancerUS
Mutlay Sayan, MD retweeted
What happens when GU experts tackle the toughest real-world cases together? Next at #WorldGU25, @bilenma (Chair), @MRHarrisonMD, @Scarps_kristen, Elizabeth Kessler, MD, @MutlaySayan & @JohnPhillipsMD lead an unmissable session: Case-Based Therapeutic Interventions in GU Cancers β Maximizing MDT Resources. hubs.la/Q03D_nRN0 #guoncology
Mutlay Sayan, MD retweeted
Excellent editorial on the DADSPORT meta-analysis: sciencedirect.com/science/arβ¦
Mutlay Sayan, MD retweeted
Congratulations to our HROP Class of 2025 - excited to see you flourish in the next step of your careers as attendings, physician scientists, and leaders in medicine, you are all wonderful! π₯²
Mutlay Sayan, MD retweeted
1οΈβ£ Elective Regional Nodal Irradiation in Prostate Cancer
π₯ With @DrSrinivas_C, @MutlaySayan & @a_dalpra
π― We cover rationale, patient selection & key trials shaping WPRT in high-risk, SBRT and post op settings.
Read π doi.org/10.1016/j.semradonc.β¦
Mutlay Sayan, MD retweeted
During residency, when modems crackled and PubMed barely loaded, I relied on Sem in Rad Oncol for the latest info.
Contributing 2 articles to its latest issue on #prostatecancer is a full-circle moment. ππΌ
What @sophia_kamran and @CZamboglou have put together is a masterpiece.
Mutlay Sayan, MD retweeted
β¨Insightful (and must-read) editorial by @MutlaySayan & @DrPaulNguyen in @EUplatinum :
β‘οΈAs ADT shows modest OS benefit post-prostatectomy, the future lies in precision, leveraging PSMA PET, genomic classifiers, and AI to guide who really needs treatment intensification.
@OncoAlert @APCCC_Lugano @DrYukselUrun @PCFnews #ProstateCancer #Cancer #Oncology #MedTwitter
Link:
europeanurology.com/article/β¦
