Endocrine and Thoracic Surgical Pathology. Author of Endocrine Pathology and Patología de la glándula Tiroides. Editor in Chief of Archivos de Patología.
Joined November 2012
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Severino Rey MD, PhD retweeted
This came to me as negative for malignant cells from the cytotech. These deceptively bland cells are all basically all malignant and BER-EP4 positive. Take a guess about their origin. #boardfodder
Severino Rey MD, PhD retweeted
Just a bread and butter case: with better control of HIV disease it is easy to forget about Kaposi sarcoma - this example with hyaline globules. (erythrophagolysosomes).
Severino Rey MD, PhD retweeted
Adult with a sellar mass. Diagnosis? What symptoms might have manifested? What's the likelihood of recurrence? #pathology #neuropath #pathtwitter
Severino Rey MD, PhD retweeted
What's the diagnosis of this fourth ventricular tumor in an adult? The tumor has mutations in NF1, FGFR1, and PIK3CA. (It's a Rare, Generally Nonaggressive Thing.) #pathology #neuropath #pathtwitter
Severino Rey MD, PhD retweeted
CLASSIC and gorgeous cytomorphology - a jumbled capillary network weaving through deceptively bland neuroendocrine cells from an intrathyroidal parathyroid neoplasm (adenoma) - "the vascularity and naked nuclei are the clues". (Thyroid, FNA)
Severino Rey MD, PhD retweeted
We are honoured to welcome Prof. @ReyPathology , MD, MSc, Ph.D, IFCAP to the Editorial Board of Global Pathology Publications.
Prof. Rey is President of the PathoExpert International Academy and a distinguished expert in endocrine, thoracic, and head & neck pathology. As an accomplished author and editor of pathology publications and specialized atlases, his work has contributed significantly to pathology education and professional knowledge.
His expertise and international perspective will be invaluable as we continue building a truly global platform for pathology.
Welcome to the Global Pathology Publications family, Prof. Rey.
Severino Rey MD, PhD retweeted
"Cannon Ball Overload" - A case from today's sign-out, cell block and cytospins. (Metastatic breast ductal carcinoma, Pleural fluid)
Severino Rey MD, PhD retweeted
"A soccer ball in the CSF - except this goal belongs to Cryptococcus."
Severino Rey MD, PhD retweeted
Unusual Breast Lesions
Reactive Angioendotheliomatosis (Diffuse Dermal Angiomatosis)
A florid vascular proliferation driven by tissue hypoxia, often linked to severe cardiovascular disease, chronic kidney disease, or obesity
• Does not dissect through terminal duct-lobular units • No nuclear atypia, endothelial multilayering, increased mitoses, or necrosis
⚠️ Diagnose with caution in the breast, always correlate thoroughly with clinical history
Dr. Cimino Mathews #USCAP #pathology #PathX #PathTwitter #BreastPath
Severino Rey MD, PhD retweeted
Another advice for the interns. No matter how unusual the cytomorphology looks, "Every UNKNOWN primary has a KNOWN history - if you investigate." (Metastatic colorectal adenocarcinoma, pleural effusion)
Severino Rey MD, PhD retweeted
Breast vacuum core biopsy with this sole lesion. Any thoughts on the diagnosis? What is the clinical implication of the diagnosis?
#pathology #IHCpath #breastpath
Severino Rey MD, PhD retweeted
A nice contrast between alveolar macrophages and cells from a small cell carcinoma. (EBUS FNA, lung lesion)
Severino Rey MD, PhD retweeted
“Pure invasive micropapillary carcinomas may be associated with multinucleated osteoclast-like giant cells, which may be as large as the micropapillary clusters”
WHO 6 Bluebook 📖
#Breast #Pathology #PathX #PathTwitter
Severino Rey MD, PhD retweeted
Best example of "checker board" (speckled) chromatin pattern on a brain aspirate - Metastatic Small Cell Carcinoma. (paraventricular lesion)
Severino Rey MD, PhD retweeted
More "Turtles on the Beach" - Despite the presence of focal stromal matrix, this parotid FNA turned out to be a "Low-grade Myoepithelial Carcinoma".
FNA called "Neoplasm-SUMP, with myoepithelial differentiation".
Severino Rey MD, PhD retweeted
***Lepidic pattern is not limited to primary lung tumors***
- Female patient with history of breast cancer now with lung lesion (pic 1 and 2): Mesothelioma, epithelioid type
- Melanoma (pic 3)
- Cholangiocarcinoma (pic 3)
Practical lession: Lung tumors that looks like carcinoma but negative for TTF-1 and p40, add Claudin 4 and WT-1 to exclude the possibility of mesothelioma
Dr. Sauter #USCAP2026 #pathology #PathX #PathTwitter
Severino Rey MD, PhD retweeted
A study in Head and Neck Pathology analyzes 23 cases of oral carcinoma cuniculatum (CC) and classifies them into three groups: CC, conventional OSCC, and uncertain CC. This classification aids in understanding their distinct characteristics.
bit.ly/4efTQIo