Frankel lab, Imperial College London. #microbiome #hostpathogen #t3ss - Tweets from lab members.
Imperial College London
Joined October 2018
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Frankel Lab, Imperial College London retweeted
Thank you, Gadi @TheFrankelLab, for visiting us in Gifu and for the wonderful talk with many inspiring topics!
We totally enjoyed your lecture and the pleasant time over dinner and the Ukai cruise with you❣️
Frankel Lab, Imperial College London retweeted
New paper from the lab now published @NatureComms We show that NETs drive immunopathology in exacerbated #COPD. Work led by the talented @OrestisKats (now moved onto pastures new) with help from our friends @ProfJDChalmers group.
nature.com/articles/s41467-0…
Frankel Lab, Imperial College London retweeted
Subset of absorptive colonic epithelial cells elicit MHCII-dependent help from IL-22+ T cells to orchestrate regional immune protection against Citrobacter in the intestine @Nature @cgarrettwilson Weaver & Zindl
nature.com/articles/s41586-0…
Frankel Lab, Imperial College London retweeted
How does Salmonella infection become persistent? We are so proud to share our publication in @cellhostmicrobe
Congratulations to Alex, Bar, Jonathan, Ashlee and all the coauthors. That was an amazing journey with @sheba_medical and @broadinstitute
sciencedirect.com/science/ar…
Frankel Lab, Imperial College London retweeted
Excellent news for @PharmaT3 and for the whole field of therapeutic synthetic bacteria !
German pharma company acquires University of Basel start-up for 450 million Swiss francs | University of Basel unibas.ch/en/News-Events/New…
Frankel Lab, Imperial College London retweeted
New publication from the TacC Lab in collaboration with the Erhardt Lab. A long-awaited proof of DNA transfer via the extended conjugation pilus.
pnas.org/doi/10.1073/pnas.23…
Frankel Lab, Imperial College London retweeted
🦠 Research from @CBRB_Imperial shows that antibiotics promote the growth of antibiotic-resistant bacteria in the gut.
The study could lead to better patient risk assessment and treatments to help combat antibiotic-resistant bacteria. ⤵️
imperial.ac.uk/news/247213/a…
Frankel Lab, Imperial College London retweeted
Proud to share our latest discovery: Bacteria conjugate ubiquitin-like proteins to interfere with phage assembly
A new concept in antiphage immunity, and a mechanism for ISG15-like antiviral defnese in bacteria. Big congrats to talented @Jens_Hoer!
A 🧵
biorxiv.org/content/10.1101/…
Frankel Lab, Imperial College London retweeted
Thanks to @gileadamit @TheEconomist for wading into the world of SaPIs and phages! Making science accessible to the public is tough work. I can barely explain it to other scientists!
Tiny hitchhikers on viruses could promote resistance to antibiotics economist.com/science-and-te…
Frankel Lab, Imperial College London retweeted
Check out how hypervirulent #Klebsiella pneumoniae can inversely regulate mucoid #capsule while upregulating Type 3 fimbriae expression under changing iron conditions! All through previously uncharacterized protein in the #salmochelin cluster.journals.asm.org/doi/10.1128…
Frankel Lab, Imperial College London retweeted
Proud of this work in which Klebsiella helps to uncover new immunology, this time the activation of MAIT cells by type I IFN rupress.org/jem/article/220/… @JExpMed Superb leadership by @BarralLab , a privilege to collaborate with her team.
Frankel Lab, Imperial College London retweeted
It's finally out! If you are interested in NK cell responses and memory to bacterial infection, you can read our new paper. Enjoy...
Streptococcus pneumoniae drives specific and lasting NK cell memory @Chrom_Inf @Tiphaine_cam
@ImmunOrhan @juliatorne @PLOSPathogens
journals.plos.org/plospathog…
Frankel Lab, Imperial College London retweeted
We have a funded PhD student position open !
The young researcher will study the impact of co-exposure to a bacterial toxin and food contaminants on urinary tract infection.
The programme is co-supervised by our team and Isabelle Oswald's team in Toulouse.
Frankel Lab, Imperial College London retweeted
At the Fleming Centre, scientists will work alongside patients, members of the public and policy makers to scope, test and scale solutions, so that antimicrobials can continue to keep the world safe.
Watch to find out more ⬇️
ow.ly/6eJV50PkqZz
Frankel Lab, Imperial College London retweeted
Fantastic that this work is now out! It was hugely impacted by the pandemic (especially work with new mice), but @MishraVS & @cp_anna and many others worked tirelessly to see this through. We present mechanisms of pro-IL-1b ubiquitylation & turnover.. 🧵
nature.com/articles/s41467-0…
Frankel Lab, Imperial College London retweeted
🎉 Here's our recent work on the identification of enteric fever-specific antigens for population based serosurveillance academic.oup.com/jid/article…
@Baker_Lab_Cam @hefili
Frankel Lab, Imperial College London retweeted
Our work is out @PNASNews.
We introduce scPAIR-seq: a high-throughput method for paired host profiling with multiplex-tagged bacterial mutants to analyze host-pathogen at single cell resolution.
Congratulations to Ori Heyman and @noabossel
pnas.org/doi/10.1073/pnas.22…
Frankel Lab, Imperial College London retweeted
WHO outlines 40 research priorities on antimicrobial resistance who.int/news/item/22-06-2023…
Frankel Lab, Imperial College London retweeted
New preprint from the Lab! Now we know ! The F pilus can serve as a conduit for the DNA during conjugation between distant cells biorxiv.org/content/10.1101/…
Frankel Lab, Imperial College London retweeted
I’m thrilled to let you know that we have just recruited a new professor to join our department: Prof. Mariagrazia Pizza. She is one of the world’s most accomplished researchers in vaccine development. @ImperialSci @ImperialLifeSci