@UCSDChangLab

Studying #TCellMemory in #immunity and #IBD @UCSanDiego

 La Jolla
changlab.ucsd.edu
Joined April 2020
  • Tweets72
  • Following299
  • Followers485
3Media
A privilege to write this @NEJM review article on IBD pathophysiology. Remarkable insights across many scientific disciplines including #genetics #microbiology and #immunology have substantially advanced our understanding of #IBD. nejm.org/doi/full/10.1056/NE…

Pathophysiology of Inflammatory Bowel Diseases | NEJM

Research on IBDs has identified disrupted immune responses in the gastrointestinal mucosa and putative disruptions in the gut microbiome as causative agents. This work has led to better therapeutic...

nejm.org
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New research from @UCSDChangLab identifies context- and anatomy-specific roles for the transcription factor #Foxo1 in regulating intestinal tissue-resident memory CD8 #TCells in mice. Learn more in Science #Immunology: scim.ag/4cuCVzh
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The transcription factor Foxo1 has context-specific roles in the regulation of intestinal TRM cells @SciImmunology @UCSDChangLab science.org/doi/10.1126/scii…
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Our latest story now out in @SciImmunology Congratulations to Paul Hsu and Eunice Choi who led the study together! Grateful to our long-time collaborators Wei Wang @GoldrathLab @yeo_lab @ZunigaLab science.org/doi/10.1126/scii…
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I expect no less from the King of Pathogens 🤣
ChrisHunter@KingOfPathogens3 Mar 2025
Replying to @immunologyUCSD @pennvet @ljiresearch @ucsdbiosciences @UCSDBMS @salkinstitute @scrippsresearch @sbpdiscovery @UCSDHealthSci
Its going to be amazing!🙄
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The Program in Immunology welcomes Dr. Christopher Hunter @KingOfPathogens from @pennvet. Please join us for his seminar!
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The Program in Immunology welcomes Dr. Joseph Sun @SunLab_Official from @MSKCancerCenter and @WeillCornell. Please join us for his seminar on Wednesday February 5!
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The Program in Immunology welcomes Dr. Stefani Spranger @stefanispranger from @MITBiology and @kochinstitute. Please join us for her seminar on Monday January 13!
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The Program in Immunology welcomes Dr. Alison Ringel @alisoneringel from @MITBiology and @ragoninstitute. Please join us for her seminar on Wednesday December 18!
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Drs. Kaech, Glass, and Hedrick will each give lectures at this Special Symposium, which will be followed by a happy hour. Please join us!
Program in Immunology@immunologyUCSD30 Oct 2024
Please join us on November 13th for a special symposium celebrating our newly elected members of the National Academy of Sciences: Dr. Susan Kaech, Dr. Christopher Glass, and Dr. Stephen Hedrick.
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Geting ready for some exciting science, starting soon...
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Thank you @DrTineJess for your visit to @UCSDHealth. We were all incredibly inspired by your work @PREDICTIBD and look forward to future collaborations and interactions!
PREDICT IBD@PREDICTIBD12 Jun 2024
Replying to @DrTineJess
@DrTineJess visiting our great collaborators at @UCSDHealth to give a lecture on Danish health data and biobanks and to work with collaborator Dr. #SiddharthSingh and team. @aalborg_uni @AalborgUH @GrundforskFond @ShailjaShahMD @UCSDChangLab @Eric_Low_GI #LarsEckmann and more
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Register before 6/14 for the #AAIIntro Course: aai.org/Education/Courses/In… Come learn from experts in the field of #immunology, including faculty from the Program in Immunology! @Idoyaga_Lab @UCSDChangLab @profshanecrotty @Dani6020 @mraffatellu
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John Chang retweeted
Alex Monell@almonell26 Mar 2024
Our team (@MReinaCampos @MaximilianHeeg @GoldrathLab @UCSDChangLab @yeo_lab) used single-cell spatial transcriptomics to study antigen-specific Cd8 T-Cell (P14) responses to acute systemic viral infection in the small intestine. Check it out on biorxiv! biorxiv.org/content/10.1101/…
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John Chang retweeted
Immunity@ImmunityCP13 May 2024
Check out this article featuring some of our favorite submissions from our #Immunity30th Anniversary cover contest! Learn more about the creative immunologists who made these beautiful covers and what inspires them! cell.com/news-do/immunity-30… @elnlnx @gabyrabi @Honda1Kenya @frarro1 @johanna_emgard @Lars_Hangartner @DennisRBurton @darwid_sci_art
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Congratulations to Elena Lin @elnlnx on her design for @ImmunityCP's wonderful 30th Anniversary issue! So proud of Elena's many artistic and scientific accomplishments!
Immunity@ImmunityCP9 Apr 2024
(1/3) Our 30th Anniversary issue is online! To celebrate with the immunology community, we hosted an open call for cover submissions & were grateful to have received beautiful & creative submissions from across the world! The winning design featured on the cover of this anniversary issue was designed by Yun Hsuan Elena Lin, a Ph.D. candidate in the laboratory of Dr. John Chang at UCSD @elnlnx cell.com/immunity/issue?pii=…
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The Program in Immunology welcomes Dr. Romina Goldszmid from @NCIResearchCtr @NIH. Please join us for her seminar on Monday February 5!
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Congratulations to the 2023 @BioLegend Fellowship awardees Alicia Gibbons and Alexandra Stream! Read more about their research here: immunology.ucsd.edu/support/…
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John Chang retweeted
Immunity@ImmunityCP22 Dec 2023
As we get ready for 2024, let's look back at the Immunity covers of 2023! Thank you to everyone that contributed to the science & art in these beautiful, creative covers! And thanks to everyone who chose Immunity as their niche this year! 😜 What's your favorite cover?
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Congratulations to Professor Hiutung Chu @theChuLab @UCSanDiego! The lab's first paper, led by @avayala14, is recently published @JExpMed
Dr. Hiutung Chu 朱曉彤 @chulab.bsky.social@theChuLab14 Dec 2023
Exciting news! Our lab’s first paper is published in JEM 🎉 Led by Adriana Vasquez Ayala @avayala14, we show that commensal bacteria, such as Bacteroides fragilis, employ type IFN pathways to promote immune tolerance. doi.org/10.1084/jem.20230063

Commensal bacteria promote type I interferon signaling to maintain immune tolerance in mice

Commensal bacteria, such as Bacteroides fragilis, triggers type I IFN and IL-27 in DCs to influence Tregs through IL27RA signaling. The IFN gene signature

rupress.org
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Congrats Ananda! @GoldrathLab
Program in Immunology@immunologyUCSD8 Nov 2023
Congratulations to Professor Ananda Goldrath @GoldrathLab for receiving this prestigious award @CancerResearch⁩!
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