@YRMeng

Epigenetics. Stem cell. Hematology. Immunology. @UniofOxford, @MRC_WIMM, @MRC_MHU.

 Oxford, England
Joined May 2011
  • Tweets106
  • Following112
  • Followers69
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Excited to share that my postdoctoral work is finally out @NatureCellBio, thanks to all the great people @Simona66274422 @SThongjuea I've been working with @UniofOxford @MRC_WIMM. What a journey! nature.com/articles/s41556-0…
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FlowJoのライセンスをどうするべきか悩んでましたが、今はFloreadaという解析ツールがあるんですね。使った感触はかなりよい。しかも無料！ floreada.io/analysis
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nini
@nini_incrypto_May 19
Claude Code 正式进化为科研助理Claude-Scholar！ 它解决了科研中最耗时的环节： 1.全自动文献综述：支持 Zotero 同步，帮你自动整理文献。 2.数据实验分析：直接处理真实统计数据并给出结果。 3.论文全流程支持：从写作、反驳意见（Rebuttal）到演示幻灯片一条龙搞定。 4.内置 Obsidian 知识库：让你的研究笔记自动系统化。 github.com/Galaxy-Dawn/claud…

GitHub - Galaxy-Dawn/claude-scholar: Semi-automated research assistant for academic research and...

Semi-automated research assistant for academic research and software development. Supports Claude Code, Codex CLI, Kimi Code CLI, and OpenCode across ideation, coding, experiments, writing, and pub...

github.com
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Yiran Meng retweeted
Tom Dörr
@tom_doerrFeb 8
Equips Claude with skills for scientific research workflows github.com/K-Dense-AI/claude…
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Teaching a new course @Stanford this quarter on explainable AI, motivated by neuroscience. I have curated a paper list 4 pages long (link in comment). What are your favorite papers on explainable AI/mechanistic interpretability that I am missing? Please comment or DM. thanks!
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On arXiv, there’s a 200+ page overview book on AI and LLMs available. Covers pretty much all the fundamentals.
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We are excited to announce the release of the @enGenome_srl VarChat track for hg38 and hg19. This track uses AI to search papers for variants, providing information such as its gene, HGVS nomenclature, and dbSNP rsID. Learn more at genome.ucsc.edu/goldenPath/n….
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Jimmie Ye@yimmieg24 Oct 2024
1/🧵Excited to re-introduce Memento in (cell.com/cell/fulltext/S0092…), a scalable method for differential analysis of scRNA-seq data. It provides first-in-class performance in statistical power and calibration for comparing differences in mean, variability, and gene correlation.👇

Method of moments framework for differential expression analysis of single-cell RNA sequencing data

Memento implements a statistical model and a fast resampling procedure to estimate and compare the mean, variability, and correlation of gene expression, allowing for the study of transcription in a...

cell.com
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💡Thinking of using scRNA-seq to design antibody panels for spatial or single-cell profiling? Happy to launch Cytomarker, an interactive web-app and new antibody screening strategy to design and validate custom panels 1/6
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📣Excited to share our new study in @NatureMedicine that @KexinHuang5 , @marinkazitnik, and I have been working on for the last four years! TxGNN is a graph-based foundation model for zero- shot drug repurposing that can find therapies for diseases with zero treatment options.
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soria
@jsoriamd30 Sep 2024
The integration of #cancer #biomarkers has revolutionized cancer treatment, allowing remarkable advancements in cancer therapeutics & the prognosis of cancer patients. This review paints the road ahead. sciencedirect.com/science/ar…
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Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab @NatureMedicine @GeneCollector @xrtGenomics nature.com/articles/s41591-0…
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Coordinated, multicellular patterns of transcriptional variation that stratify patient cohorts are revealed by tensor decomposition go.nature.com/47ARizC
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CellChat for systematic analysis of cell–cell communication from single-cell transcriptomics nature.com/articles/s41596-0…
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The first and last review written in my postdoc days. I may have left academia, but it's always fun to talk about HSCs.🥸🥸
Trends Cell Biology@TrendsCellBio13 Sep 2024
Epigenetic regulation of hematopoietic stem cell fate dlvr.it/TDCf6y
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Long-read sequencing for 29 immune cell subsets (Transcriptomic Resource of Immune Cells using Long-read Sequencing, TRAILS) reveals disease-linked isoforms nature.com/articles/s41467-0…
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Single-cell multi-ome regression models identify functional and disease-associated enhancers and enable chromatin potential analysis | Nature Genetics nature.com/articles/s41588-0… #Bioinformatics
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Accurate and sensitive mutational signature analysis with MuSiCal | Nature Genetics nature.com/articles/s41588-0… #Bioinformatics
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A neoadjuvant treatment regimen of anti-PD-L1 #immunotherapy followed by anti-PD-L1 + chemotherapy was well tolerated and led to pathologic response rate of 70% in patients with resectable #GastricCancer or GEJ adenocarcinoma @MyriamChalabi @NKI_nl nature.com/articles/s41591-0…
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Juhyun Kim@juhyunk_23 Jan 2024
Mosaic integration and knowledge transfer of single-cell multimodal data with MIDAS nature.com/articles/s41587-0… #journals #feedly

Mosaic integration and knowledge transfer of single-cell multimodal data with MIDAS

Nature Biotechnology - Single-cell, multiomic datasets are integrated using dimensionality reduction, imputation and batch correction.

nature.com
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CAR-T cell manufacturing: Major process parameters and next-generation strategies. A new review by Melanie Ayala Ceja, Yvonne Y. Chen and colleagues @UCLA hubs.la/Q02gDYfy0 #Immunotherapy #CancerFocus #leukemia #lymphoma
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