Anderson Cancer Fellow in @RoutLab_RU | Love a good mural | Here for the memes.
NYC and Philadelphia, PA
Joined June 2009
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- Following287
- Followers250
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Trevor Van Eeuwen retweeted
Excited to share our new @ScienceMagazine paper! Led by postdocs Ruchao Peng and Xin Xu, we used cryo-EM/ET to reveal the influenza ribonucleoprotein complex structure and its strand-sliding mechanism for RNA synthesis, paving the way for new antivirals.
science.org/doi/10.1126/scie…
Trevor Van Eeuwen retweeted
Thrilled to share our work with the Ben Black Lab, led by a co-mentored star MD/PhD student Katie Kixmoeller (@PennMedicine,@BMBGGUPENN,@BB_UPenn), now in @CellCellPress! We used cryo-ET to study kinetochore features in human mitotic chromosomes. 🧬🔬❄️
authors.elsevier.com/c/1kUW9…
Trevor Van Eeuwen retweeted
Can't believe I get to say this, BUT...just started as an assistant professor @BiophysicsJHMed @HopkinsMedicine! So excited to work with all of my new colleagues in the Hopkins Biophysics community!
Trevor Van Eeuwen retweeted
Our work on the architecture and model of the #NuclearBasket is now out @CellCellPress. cell.com/cell/pdf/S0092-8674…. @HHMINews, @IntActOme #NPC #teamtomo
A short tweetorial follows
Trevor Van Eeuwen retweeted
From preprint to journal. Our nuclear gatekeepers have successfully unlocked the gates to Cell (Journal) cell.com/action/showPdf?pii=… #NPC #integrativemodeling Congrats to team @dgvjayS @JoshHutchings94 @ig_ech @RoutLab_RU @salilab_ucsf @TheVillaLab Animation youtube.com/watch?v=LiKdFIxr…
Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling biorxiv.org/content/10.1101/…
Trevor Van Eeuwen retweeted
Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells!
biorxiv.org/cgi/content/shor…
Trevor Van Eeuwen retweeted
Following up our work describing FLVCR1 as a high affinity choline transporter @KivancBirsoy @ArtemAKhan, excited to share our recent work in close collaboration with @Yeeun_Jecy_Son @HiteLabMSKCC describing the structure and mechanism of action of FLVCR1!
nature.com/articles/s41586-0…
Trevor Van Eeuwen retweeted
Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling biorxiv.org/content/10.1101/…
Proud to share the result of an amazing collaboration with Javi Fernandez-Martinez, @RoutLab_RU , and @TheVillaLab ! biorxiv.org/content/10.1101/… Congrats to @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech and the team!
And check out the video by @neeleshsoni03 ! #NPC
Trevor Van Eeuwen retweeted
It cannot be done, they said.. It's too flexible, they said.. 😁
biorxiv.org/content/10.1101/… #NPC #teamtomo #integrativemodeling by @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech et al. Great collaboration w/ Qiang Guo, Brian Chait, Javi Fernandez-Mtnz, @RoutLab_RU @salilab_ucsf
Trevor Van Eeuwen retweeted
Please repost!
Arimura Lab is hiring! We are seeking the next generation of MagICians (technicians and a postdoc) to elucidate the structural basis of events on chromosomes🧙♀️
No prior structural biology experience is required!!
Link
research.fredhutch.org/arimu…
Trevor Van Eeuwen retweeted
My first postdoc publication, and, more importantly, my first work with the great @greatysp and @ElaineFuchsLab 🎉
The tumour microenvironment and epigenetic changes play a critical role on cancer biology. Read our Review here! 👇🏼
Fresh out of the oven! Our new review in @NatureRevCancer explores the non-genetic drivers of tumorigenesis and progression. It’s not all down to mutations!
Good job @greatysp and @almagro_jorge 👏🏼
nature.com/articles/s41568-0…
Trevor Van Eeuwen retweeted
Very proud of this work on L1 DNA methylation & expression led by @sophie_lanciano & Claude Philippe, now online @CellGenomics
cell.com/cell-genomics/fullt…
#proudPI #Transposon #TE @CellPressNews @ircaninstitute @Insermpacacorse @Inserm @CNRSbiologie @Univ_CotedAzur
A long 🧵 1/15 👇
Trevor Van Eeuwen retweeted
Genomic dark matters are important for understanding and treating cancer. Joint work with @leung_holden , @XuanCircleQu and @Nakul2234.
Trevor Van Eeuwen retweeted
Thrilled to announce our paper @Nature, >10 yrs in the making! I led an amazing team to finally crack structures and mechanisms of LINE-1, with implications for cancer, autoimmunity, and other diseases. We made a video abstract with @visualscience narrated by my mentor @JefBoeke
So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in @Nature nature.com/articles/s41586-0…
Trevor Van Eeuwen retweeted
Can't even describe how challenging but joyful this project was! Check the thread by @_themovingvan_ describing our journey for the G̶o̶l̶d̶e̶n̶ ̶F̶l̶e̶e̶c̶e̶ structure of LINE1 ORF2p in @Nature ! nature.com/articles/s41586-0…
So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in @Nature nature.com/articles/s41586-0…
Trevor Van Eeuwen retweeted
New Degradation Tag using eDHFR published online today in @NatureComms from @sellmyerlab - complementary with and orthogonal to dTAG!
nature.com/articles/s41467-0…
Trevor Van Eeuwen retweeted
Excited to finally share my first author publication out today @NatureComms addressing the molecular determinants N-WASP and Cortactin synergistic activation of Arp2/3 complex! Huge thanks to the whole team! Open access: nature.com/articles/s41467-0… – at Philadelphia, PA
Trevor Van Eeuwen retweeted
Incredibly excited to share the latest and greatest from the lab, where we used cryo-EM and Alphafold2, to determine a composite, integrative multi-scale model of the yeast Nuclear Pore Complex (NPC), now live @MolecularCell
cell.com/molecular-cell/full…
Trevor Van Eeuwen retweeted
Incredibly excited to share our newest collaborative preprint where we examine the nature of the permeability barrier of nuclear pore complexes (NPCs) biorxiv.org/content/10.1101/…
Trevor Van Eeuwen retweeted
Highlighting #WomenInSTEM, Jean Etersque (BS @FDUWhatsNew) is a PhD Cand. in @BB_UPenn @BMBGGUPENN in @sellmyerlab @PennRadiology and former president of @pgwise_upenn. Jean shares her motivation in science and research #WomensHistoryMonth
