Writer/Director of God Will Find Me (2026). Former standup. Takes on AI, tech, human nature. NYC. https://teapawt.org/t.co/MZdP929Y8A
New York, NY
Joined July 2009
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Bennett Hoffman retweeted
I don't think people realise how big a deal this is.
If you have cancer, or somebody you know has cancer, there is a company in Hyderabad that wants to build a personalised cancer vaccine for you.
Try approaching any big pharma company and asking for a personal vaccine. If they even reply to your email, this is the response you'll get: we don't do that here.
PopVax, on the other hand, takes your tumour sequencing data (or a sequence you've designed), designs candidate neoantigen vaccine sequences with their AI pipeline, produces the mRNA, encapsulates it in their LNP formulation, fills vials, and runs QC, all in 8 to 10 weeks. They’re publicly committing to capacity for 100+ of these over the next 12 months and asking people to email them their cancer type/stage and sequencing details.
What a time to be alive.
Bennett Hoffman retweeted
the old education system is like dead dead
there's literally never been a better time in history to homeschool your kids with AI
you can now just prompt it to create an entire curriculum for your kid, give lessons, generate interactive quizzes to see what they're actually learning, explain things in a hundred different ways until they understand, adapt the difficulty and pace to their progress, generate videos, etc etc
you could probably give your kids a much better education in a fraction of the time they'd otherwise spend sitting in a classroom learning the same things at the same pace as 30 other kids
and then spend all that extra time playing with them, exploring, doing sports, reading, traveling, whatever
it's actually insane when you think about it
Physics is hard to visualize through static images alone, so I turned my 174 pages of high school physics notes into an interactive website.
It covers mechanics, electricity, and magnetism, breaking down complex concepts into intuitive visualizations, real-world scenarios, and interactive problems.
Check it out here: atlas-of-physics.vercel.app/
Bennett Hoffman retweeted
Our second product is called Blindsight and it will, as the name suggests, enable even those who are completely blind or have never seen to see.
It is ready from an engineering standpoint. Just waiting on regulatory approval.
Bennett Hoffman retweeted
No. We've got to stop applying old human-centric patterns to working in the new era.
delete all your wikis.
have an agent answer questions from source instead.
at spawn we have:
- zero dashboard tools
- zero docs
- we do not make or use summaries
everything we do is primary sources + intelligence
Nothing to go stale
Nothing to organize
Nothing to navigate
Always exactly up to date
Perfectly personalized
The answers get better with every model
If we want to see a chart, we ask for it, and we have it in a minute
If we want an answer to a question, we ask it, and we have a to-the-minute correct answer
Bennett Hoffman retweeted
BREAKING: For the first time in American history, the Department of Energy has approved a commercial nuclear microreactor's safety analysis for full-power operations.
LA-based Radiant secured the approval, with testing planned at Idaho National Laboratory.
ALT Source: Radiant Rendering
Bennett Hoffman retweeted
The Alaska story may have a real impact…
Mary Peltola looked voters in the eye and lied about it every time she was asked. She pretended this "Dan Sullivan" was a random man who decided to run, when really it was a scheme they were planning for over a year.
It’s time…
📍2026 MIDTERM PREDICTION
My House + Senate prediction, specific races I bet on, and key early bellwethers to watch:
geigercap.com/p/2026-midterm…
What if you just had a README.md for agents to implement their own client libs?
Obviously this just pushes the issue up a level of abstraction, but it's probably easier for both human reviewers and agentic security audits to catch vulns in plain english at the spec level.
I would strongly consider uninstalling any third party js right now if I were you. Especially if it comes from a startup.
Analytics, monitoring, etc are all massive site takeover risks. If you use a tracking script from a third party SaaS, then if they get hacked the hackers have total control over your site too.
This is what took down Polymarket today. They used a tiny script from a SaaS that tracks page load speed. That company got hacked, and the hackers subsequently stole millions from Polymarket users.
If you want to use analytics safely, I would use a product that lets you pin the tracking script and control when it changes. Most of the mature products support this, e.g. Sentry, Amplitude, PostHog, Mixpanel, Heap. If not, you need to trust the company behind it a lot...
Railway got hacked last week. Railway! That's a very competent team, with particularly strong infra chops. The agent swarms are on another level.
A typical analytics company is nowhere near as sophisticated. You should ask yourself: do I trust this company's security more than Railway? I was an analytics CTO in a past life, and I will be the first to admit: we had some great people but we were not on this level.
We (Detail) just uninstalled our session replay, which was a product I loved but is not worth the risk right now.
I hate to write this because I spent a good chunk of my 20s benefitting from product teams taking a chance on a nothing startup and installing our js on their site. But in the past two weeks this risk vector has exploded. It's better for the ecosystem if we move away from third party js as fast as we can.
Bennett Hoffman retweeted
one reason ive become less interesting is that people no longer pretend to believe in things and so there are no beliefs to interrogate
most politics is explicitly schmittian now and no one is even bothering with the window dressing. people just want to kill each other
Bennett Hoffman retweeted
there is a computer at the end of time reaching back to modify our world so that we are guaranteed to build it. there are signs everywhere if you have the eyes to see.
Bennett Hoffman retweeted
The strongest form of AI doom is some kind of novel self replicating nanobot that rapidly transforms the planetary ecology wiping out all previous life.
This has actually happened once before.
It is why we have an oxygen atmosphere today
Cyanobacteria killed 99% of all life
Bennett Hoffman retweeted
this is one of the most positive developments in the history of machine intelligence
Bennett Hoffman retweeted
In 2020, we were fighting just to keep nuclear plants from closing early.
Almost everyone said it was pointless. Nuclear was dying, and that was that.
Now @SecretaryWright is standing in front of a plant talking about squeezing more power out of 15 reactors.
We're restarting plants that were shut down. We're talking about building new ones.
The biggest lesson from watching this turn happen up close:
What looks inevitable usually isn't. It changes when the right group of people decides to care.
.@SecretaryWright: “The plan is to take 15 reactors at 8 different locations and uprate them. Meaning the plant behind me would get another 150MW of power output...
Significantly more energy, puts downward pressure on rates, allows more manufacturing, more jobs to be created."
Bennett Hoffman retweeted
Windows Copilot was so terrible it might very well have seeded the AI opposition we now see among normies. Useless functionality, hyped to the moon, and a dumb key on every keyboard that did nothing worthwhile. youtube.com/watch?v=erRVsllM…
Bennett Hoffman retweeted
It's basic hyperstition Matt. Those who hate the future will say AI and those who want to build the future will say SI. It creates two clear, distinct and non-overlapping visions of a single technology.
Obviously you continue saying AI.
I have no idea why renaming AI is so bizarrely important to Trump. Nobody cares about the name he chose. Nobody is using it or will use it. And it’s not even technically accurate because “super intelligence” already had an agreed upon, widely adopted definition. This is the weirdest political hill to die on. It gains you nothing. Not a single ordinary American in the country, anywhere, cares deeply about making sure people say “SI” instead of “AI.” We are days away from a major election and this bullshit is the focus? Just baffling.
Bennett Hoffman retweeted
I'm starting to sense a divide in the tech industry:
- People thriving on autonomy who are reinventing how they work and what tools they use with AI: LOTS of work, but they're enjoying it and getting very efficient
- People used to being mentored / trained / or simply told what to do and how. Frustrated with the lack of guidance from management on what to do with AI; also frustrated by seeing some of their peers thriving; increasingly bitter about AI and the state of the industry, as a whole
Neither group seems to be aware that there's another group, or have empathy for the other group
"the universe has a high skill cap"
Banger
there was a point before deep blue, before alphago, before navier stokes, where you could argue, if not entirely convincingly, that maybe some areas of human endeavor were already skill saturated enough that more intelligence wouldn't help much
I think there is basically no shred of credibility left for this kind of thinking now on anything where a primary input is intelligence. we know too much, we have seen too much. the universe has a high skill cap
Bennett Hoffman retweeted
Oh, I don't know, maybe he did it because you're running on a platform of "let's take all of Elon Musk's stuff and throw him in the gulag"?
