Co-Founder & CEO of women’s health diagnostics Co | ex- VP @Tally_health, ex-858tx, ex- @Genentech & @GSK | PhD @UCSF | MBA @MITSloan. 🧬 🌌 🔭
Princeton, NJ
Joined May 2014
- Tweets493
- Following642
- Followers566
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Dr. Trinna L. Cuellar retweeted
More passion!☀️
More passion!☀️
More energy!💥
More energy!💥
Another M8.8-class flare just erupted from the Sun!
Here’s SDO’s view:
Dr. Trinna L. Cuellar retweeted
A paper in @NatureElectron reports a hybrid computing system, called Brainoware, consisting of electronic hardware and a brain organoid, which can perform tasks such as speech recognition and nonlinear equation prediction. go.nature.com/489OoRu
ALT This is figure 1, which shows Brainoware with unsupervised learning for AI computing.
Dr. Trinna L. Cuellar retweeted
Isoleucine is an essential amino acid which, in excess, counters the health benefits of the mTOR longevity pathway. The @LammingLab is reporting that an isoleucine-restricted diet extends the lifespan of mice by 33% 👏 @Cell_Metabolism
Dr. Trinna L. Cuellar retweeted
Glycine may prolong life by inducing autophagy and mimicking methionine restriction. sciencedirect.com/science/ar…
Dr. Trinna L. Cuellar retweeted
Factors that accelerate epigenetic aging:
1. Smoking (worst)
2. Alcohol intake
3. Waist size
4. Body fat
5. CRP (inflammation)
6. Triglycerides
7. Childhood obesity
8. Type 2 diabetes
(Alcohol is turning out to be more toxic than we thought. Sorry) academic.oup.com/biomedgeron…
Dr. Trinna L. Cuellar retweeted
Delighted to share our latest study that tests The Information Theory of Aging. 13 years of work. Available at 11 AM EST today @CellCellPress. What’s it about? Here’s a clue from Catherine Delphia’s illustration in Lifespan
Dr. Trinna L. Cuellar retweeted
New Frost lab paper alert:
#Tau!
#Retrotransposons!
#Neuroinflammatory double stranded RNAs!
science.org/doi/10.1126/scia…
@elizabethmochoa
@PaulRamirez42
@jimrayNDC
@UTHealthBarshop
@UTHealthSA
1/9
Dr. Trinna L. Cuellar retweeted
Nice one @EricVerdin and team. Protection by NMN from the damaging effects of chemo 🐁🫀💪👏 @BuckInstitute mdpi.com/2073-4409/12/1/108
Dr. Trinna L. Cuellar retweeted
Ovarian aging predicts aging rates in other tissues. Women reaching menopause before 40 are 2x as likely to die early than those reaching it between 50-54. Reversing ovarian aging may help reverse overall aging. In mice we’ve done it. Let’s give women the option ⬇️
Dr. Trinna L. Cuellar retweeted
Reducing the levels of epigenome-altering RNA from selfish genetic elements called LINE-1s, reverses DNA methylation age and extends the lifespan of prematurely aging mice. Could this be a way to reverse normal aging? science.org/doi/10.1126/scit…
Dr. Trinna L. Cuellar retweeted
New drug reduces symptoms in 2 mouse models of Alzheimer’s by turning up trash recycling, a process that sustains stem cells & extends mouse lifespan. Drs Ana Maria Cuervo & Evris Gavathiotis @EinsteinMed are preparing for human trials @lifebiosciences 👏 tinyurl.com/mwe9a9sw
Dr. Trinna L. Cuellar retweeted
What is consciousness? New research in epileptics with electrodes planted deep in the brain shows that we still hear sounds while asleep, but we don’t process the information because we’ve activated alpha-beta waves. So cool 😎 tinyurl.com/2p9xfj68
Dr. Trinna L. Cuellar retweeted
Our first peer-reviewed article "Human Age Reversal: Fact or Fiction?" is out in @AgingCell. Check it out here! bit.ly/3akokeg
@tally_health authors: @davidasinclair, @dancingRNA, Adiv Johnson, Maxim Shokhirev, @brad_w_e
#TallyHealth #WelcomeToANewAge #aging #healthspan
Dr. Trinna L. Cuellar retweeted
New episode of Lifespan is out today about preserving & enhancing brain health 🧠
As always, it’s 💯 science-based. Hope you find it useful✌️ lifespanpodcast.com/the-scie…
Dr. Trinna L. Cuellar retweeted
I recently learned something mindblowing about the geological history of the Mediterranean Sea, and I just can't get it out of my head.
Now I'm going to make it *your* problem too. Sorry.
Hang onto your hat. This is wild.
1/
Dr. Trinna L. Cuellar retweeted
Our article about how mitochondrial & metabolic changes contribute to aging is now out @NatureRevEndo nature.com/articles/s41574-0…
Dr. Trinna L. Cuellar retweeted
Rejuvenation just got hotter lifespan.io/news/cellular-re…
Dr. Trinna L. Cuellar retweeted
Check out our latest preprint on why so many cells still have m6A after METTL3 knockout! Congratulations @HuiXianPoh!
Dr. Trinna L. Cuellar retweeted
Very interesting study that brings needed attention to unintended immunogenicity of fluorophores and exogenous proteins. However, we should be careful extrapolating these results to other mouse strains and models, particularly C57BL/6. My thoughts: 🧵1/12
Online Now: Elimination of fluorescent protein immunogenicity permits modeling of metastasis in immune-competent settings dlvr.it/SDdfLs