@konigmatt

Group Leader Systems Medicine of the Liver

 Berlin, Germany
livermetabolism.com
Joined June 2012
  • Tweets352
  • Following337
  • Followers261
42Media
Matthias König retweeted
biomodels@biomodels27 Sep 2024
🎉 Excited to share our preprint on FROG analysis ensuring reproducibility, reusability and reliability of Genome-Scale Metabolic Models! It is a true community effort, kudos to 90+ co-authors! More details here: biorxiv.org/content/10.1101/… #Reproducibility #SystemsBiology #GEM

FROG Analysis Ensures the Reproducibility of Genome Scale Metabolic Models

Genome-scale metabolic models (GEMs) and other constraint-based models (CBMs) play a pivotal role in understanding biological phenotypes and advancing research in areas like metabolic engineering,...

biorxiv.org
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ATLAS 🌐 meets in presence! We had an awesome time at our first in-person meeting in Stuttgart discussing our progress towards an AI- and simulation-based clinical decision support tool for liver tumor assessment! Check out ATLAS at isd.uni-stuttgart.de/researc…!
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🚨 Publication Alert! 🚨 Our latest interdisciplinary collaboration has led to an exciting paper. Our tri-phasic, bi-scale approach offers understanding of zonated fat accumulation, paving the way for deeper insights into liver health. Explore it here: doi.org/10.1007/s10237-023-0…
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11 strategies for making reproducible research and open science training the norm at research institutions: our paper just got published in @eLife: elifesciences.org/articles/8… - it was great being part of this large international collaboration with many great collaborators

Eleven strategies for making reproducible research and open science training the norm at research...

Researchers and administrators can integrate reproducible research and open science practices into daily practice at their research institutions by adapting research assessment criteria and program...

elifesciences.org
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🤝 Delighted to have met our project partners from #SimLivA and members of #SPP2311 in person in Magdeburg. We are pleased about the excellent opportunity for academic exchange and collaboration!
SimLivA Project Group Meeting

ALT SimLivA Project Group Meeting

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Interested in how the pancreas secrets insulin? Our pathway model of glucose-stimulated insulin secretion in the β-cell @DeepaMaheshvare provides some answers frontiersin.org/articles/10.… @qualiperf @SBML
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Congratulations to @JanekG9 for successfully defending his PhD thesis on physiologically based pharmacokinetic modeling (#PBPK) for dynamical liver function tests and Cytochrome P450 (CYP) phenotyping. 👏👨‍🎓🎉 @qualiperf #lisym
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Matthias König retweeted
qualiperf@qualiperf19 Jun 2023
An impromptu gathering of the #qualiperf modelers at the #CompModBioMed conference in Stuttgart, brilliantly organized by Nicole Radde & her @SimTechStuttga2 team. Embracing the unexpected often leads to the greatest insights.
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Today at the Computational Modeling in Biology and Medicine meeting organised by Nicole Radde & team at SimTech: @konigmatt with an impressive keynote on how modeling can be done right - #FAIR, #reproducible and using open tools. biometrische-gesellschaft.de…
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We present 11 strategies for making #OpenScience & #ReproducibleResearch the norm at research institutions, with tips for implementation & resources. Let's join hands to make these practices standard in the scientific community! #ScienceTraining 📚🤝 osf.io/kcvra/

Eleven Strategies for Making Reproducible Research and Open Science Training the Norm at Research...

Across disciplines, researchers increasingly recognize that open science and reproducible research practices may accelerate scientific progress by allowing others to reuse research outputs and by...

osf.io
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Matthias König retweeted
qualiperf@qualiperf24 Apr 2023
Gathering of @qualiperf at the Spring Meeting in Leipzig. Amazing gathering of experts discussing cutting-edge research on liver perfusion and function. Exciting to see the advancements being made in this field!" #ResearchConference
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Exciting news for liver function! Check out our preprint on the #PBPK model for #CYP2E1 phenotyping via chlorzoxazone by Jonas Küttner et al. Highly practical and reliable tool for assessing CYP2E1 activity in clinical practice. #SBML @qualiperf biorxiv.org/content/10.1101/…
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Matthias König retweeted
qualiperf@qualiperf3 Apr 2023
🎉 Congrats to M. Albadry, S. Höpfl, & M. König for winning the @qualiperf Michael Stifel Prize 🏆! Have a look at their interdisciplinary, data-driven research on periportal steatosis & its impact on pericentral drug metabolism 🔬📊 doi.org/10.1038/s41598-022-2…

Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism

Scientific Reports - Periportal steatosis in mice affects distinct parameters of pericentral drug metabolism

nature.com
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Get up-to-date with the latest developments in CellML, SBML, and SBOL with the COMBINE 2022 special issue: doi.org/10.1515/jib-2023-000… #SBML #COMBINE @combine_coord
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Excited to share that my contribution to standard-GEM is now available as preprint! Check it out: biorxiv.org/cgi/content/shor… #SBML #reproducibility
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So proud and so happy! Our Ph.D. student @l_lambers successfully defended her thesis on "Multiscale and Multiphase Modeling and Numerical Simulation of Function-Perfusion Processes in the Liver". Congratulations Dr.@l_lambers!!
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This is insane. Basically Germany has now said that postdoc contracts cannot last longer than three years, and after that, they have to be offered permanent positions (of which no one proposed how to generate). Even my own position now would seemingly be illegal. 🤦🏻‍♀️🙈
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Don't miss Harmony 2023! reproduciblebiomodels.org/ha… Registration is open and free. We've included a snapshot of the topics of interest for the April 24-27 conference in Seattle. #ai #biologicalmodels #biomodels #biomodeling #modelannotation #systemsbiology #syntheticbiology
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Our latest preprint is out: "A Consensus Model of Glucose-Stimulated Insulin Secretion in the Pancreatic beta-Cell" biorxiv.org/content/10.1101/… @qualiperf #SBML
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Matthias König retweeted
Emad Alamoudi@EmadAlamoudi23 Feb 2023
Multiscale models are helpful to understand the processes determining tissue dynamics. However, inferring such models is difficult. Here is our new #preprint with @yannik_schaelte, @morpheus_lab @JanHasenauer and many other great collaborators. Manuscript: biorxiv.org/content/10.1101/…
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