Terrance (@rustyshacklferd) profile picture
Joined February 2009
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I thought I was crazy until I found Richard Feynman. Feynman was not only among the most brilliant people on earth, but he transmitted something I've never seen in others. Thread with some lessons from his peculiar way of being:
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This is one of the most simple and profound graduation speeches. This 2002 Mr Rodgers speech is a top 10 and it was share to me by @prolificinvent and I just encoded it. It is my prayer it changes lives into eternity. This will be in YOUR AI.
I know have 41 hours of Mr. Rodgers interviews ready for encoding into YOUR AI model I am building in my garage. It was AI that that made the recommendation to mix his emotional stability into new AI models. I will report my progress.
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Okay, I lied about my next thread being API infrastructure for EMRs, but that’s because I stumbled onto something really weird that I wanted to cover first. I saw this tweet (teapawt.org/dvasishtha/status/1552…) about changes to a pharmacy benefit manager (PBM) formulary, and I got curious
Got an update to my pharmacy benefit and I’m reading through the jargon just thinking man we just don’t give a shit about patients sometimes
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Terrance retweeted
We need to get back on the Henry Adams Curve. That means recognizing that clean energy production is (a) possible and (b) morally good. The economy has been virtual for decades in large part *because* the US establishment limited nuclear energy. rootsofprogress.org/where-is…
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Great opportunity!! Come and join us to work on cutting-edge technologies and research.
Please RT: We are looking for talented #Bioinformatics #postdocjobs who want to work on @nanopore & @PacBio data from human population to diseases (#Cancer, #Parkinsons, ..). Develop your own research and methods at scale. Apply: jobs.bcm.edu/job/Houston-Pos… @BCM_HGSC @BCMFromtheLabs
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There is an HUGE amt of new sequencing instrumentation and technology on display at #AGBT22 ! 👇 (1/4)
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Rapid expansion of #NGS data & use in new apps requires better data processing tools. Accurate & efficient variant calling algorithms are critical. Element is proud to partner w/ 2 bioinformatics leaders: Google DeepVariant & @sentieon! Learn more: bit.ly/3HxscTv
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Over the coming days, memorial ceremonies for Thay will be broadcast live from Plum Village and Từ Hiếu Temple. The schedule is here: plumvillage.org/memorial/ Ceremonies organised by other Plum Village centers and sanghas around the world are here: plumvillage.org/worldwide-me…
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Thich Nhat Hanh, the Vietnamese Buddhist monk and founder of the Engaged Buddhism movement, died today in his home country of Vietnam. He was 95. lionsroar.com/thich-nhat-han…
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21 thoughts from 2021 I'd like to take into 2022:
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Replying to @PacBio
@PacBio HiFi is great for calling SNPs and small-INDELs. Read us applying @GoogleHealth's DeepVariant and @Sentieon's DNAscope. Impressive to see these #MachineLearning methods help detect genetic variants, & how much #longread sequencing tech advances. link.medium.com/R3gBTFgX2lb
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Terrance retweeted
Happy to see these updated benchmark results! DNAscope will output some non-pass variant candidates with a FILTER field set. @holtjma's earlier benchmark considered all variants, causing DNAscope to have a high recall but low precision. The new results are more balanced.
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Looking in variant calling accuracy comparison in the long read space. #genomics #bioinformatics #machinelearning #longread great team work speared ahead by @YihChii and @Chai_Arkarachai in @dnanexus medium.com/@YihChii/f6efec6b…
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Terrance retweeted
This is a good primer on variant calling in long-read space and generally reflects our experience with benchmarking both DeepVariant and DNAscope on PB-HiFi. My one (personal) deviation would be that generally DNAscope has been *much* easier to run out-of-the-box.
Looking in variant calling accuracy comparison in the long read space. #genomics #bioinformatics #machinelearning #longread great team work speared ahead by @YihChii and @Chai_Arkarachai in @dnanexus medium.com/@YihChii/f6efec6b…
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A lot of birds are flying over Colorado tonight. You're urged to keep the lights low/off to help them make their passage. #9NEWS teapawt.org/AudubonRockies/status/…
Lights out, Colorado! 12 million birds will be flying over the state tonight and tomorrow night, and we can help them by reducing light pollution. Birds are safer when you turn off or shield your outdoor lights. Learn more from #LightsOutColorado. buff.ly/3EnWzvF
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Lego k-mers of multiple sizes to teach genome assembly.
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BREAKING: Powerful vigil just ended at my apartment on 700th day of house arrest to honor the 2,000 Ecuadorians who have died from Chevron's pollution. Pictured are Amazon leader Lino Wamputsrik, artivist Giada, actor @SusanSarandon, and rock legend @RogerWaters. So grateful.
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The @signalapp vs @facebook story is remarkable. The biggest threat to @facebook is a non-profit funded by WhatsApp founders! Such a great story. What was Facebook argument for banning these ads? Too much transparency? My favorite prize fight. en.wikipedia.org/wiki/Signal…
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