We have just started the 2nd day of the #ILEP2025 Congress in Warsaw. The first session is dedicated to #statin #therapy💪 #ArmanPostadzhiyan #ZlatkoFras @GaniBajraktari @stanislawsurma @ExpertLipid

Why #upfront #lipid lowering combination #therapy should to be a GOLD standard in the management of #patients with high and very high #cardiovascular #disease #risk? Why we need to change the paradigm of short-term #risk #stratification (to 👉 lifetime risk stratification) and deviation on primary and secondary #prevention to #atherosclerosis / #atheromaplaque #progression prevention? 🤓 All the answers you may find in our new paper just published in a group of great experts - @CVR_TomaszGuzik, #LaurenceSperling, @fjpinto1960, @DrPenson , @MichaelJBlaha & @stanislawsurma in the Cardiovascular Research journal of the European Society of Cardiology. @escardio Have a nice reading ‼️ academic.oup.com/cardiovascr…

Very important meeing pf EU-RO Forum on #Diabetes and its #complications in Bucharest organized by Prof. Anca Stoian. Thanks for the Invitation💪

On Thursday I was in Ljubljana at the Transcutaneous Contemporary Interventions-Coronaries (#TCICoronaries) Meeting, where within interventional cardiologists I presented the newest data on the #upfront lipid lowering combination #therapy in #ACS patients. Our data from the Polish ACS-Registry, and the recent ILEP @ExpertLipid #recommendations indicate this as a gold standard, that may reduce the number of deaths due to MI by even 0,5 million annually, only in Polish in over 4000 patients‼️#makedifference #prevention Thank you to prof. @MatjazBunc & Prof. #ZlatkoFras for the invitation.

Our recent, just published in #EHJOpen journal by the @escardio , largest ever #metaanalysis on #FH #children #patients, showed not only a large efficacy of #lipid lowering #therapy #LLT, especially combination one, but it also clearly showed that #statin/lipid lowering therapy in children is 👉 very safe, and parents should not be afraid of treating their children with statin therapy even very early, as it is the only way to have the #lifeexpectancy of their children comparable to those without a #disease ‼️ @ExpertLipid @BytyciIbadete @ehjopen @SaDeRosa78 @fhpatienteurope academic.oup.com/ehjopen/art…

IMPORTANT from the new issue of @ArchMedSci: 2024 Polish #recommendations for the #management of #familial #hypercholesterolemia #FH in #children and #adolescents. The most important recommendations: 👉 It is advisable to use direct #LDL #cholesterol #measurement for improved accuracy. 👉 #LPA levels should be measured in all children suspected of FH. If LDL-C is calculated using the #Friedewald formula, this value should be adjusted for the Lp(a) result. 👉 Early diagnosis at 5 years of age is recommended‼️Consequently, this expert panel supports implementing lipid profile universal #screening during preventive healthcare visits at the age of 6‼️ 👉 Patients and their families should be supported by multidisciplinary care #teams comprising specialized #healthcare #professionals, including a specialist #physician, #psychologist, #dietitian, and #nursing staff. #Genetic consultation is also advisable. 👉 #Dietary #intervention should be implemented for every child with #dyslipidemia starting from the age of 2. 👉 #Statin #therapy should be considered for children aged 6–10 years. 👉 Despite using the maximum dose of #statins, achieving the LDL-C #goals may be challenging. In this case, it is advised to introduce #ezetimibe (from the age of 10 years), which inhibits cholesterol absorption in the intestines and complements the effects of statins. Congratulations to the whole team beautifully led by prof. #MalgorzataMysliwiec from the @GUMedGdansk ‼️👏👏 archivesofmedicalscience.com…

The results of our data from the #PMMHRI-#LPA #Registry and #STAR-#LPA study that were presented at the @escardio #congress in London again beautifully summarized in the @MSN. Thanks! msn.com/en-gb/health/other/r…

Important paper on the trends on #aspirin use in primary and secondary prevention in US. The trend is stable in 2ndary prevention based on guidelines, but it was significantly reduced (what is not a surprise) in primary prevention especially in older patients >70 years of age for which the risk of bleeding is higher and in those with low to moderate CVD risk (when aspirin is not recommended since 2018). In primary prevention we might use additional criteria for #aspirin use, that result in much higher benefit, including elevated Lp(a) levels and CAC-Score >100, what we suggested in our recent expert opinion paper by the @PoLACongress: archivesofmedicalscience.com… jamanetwork.com/journals/jam…

Feel invited to join us at the 4th World Congress of Clinical Lipidology in Vienna! @lipiddoctor

Pamietam nasza najwieksza na świecie meta-analizę (640,000 osób), która oceniała wpływ produktów mlecznych na zgon bez względu na przyczynę, zgony sercowo-naczyniowe i inne punkty końcowe. Wówczas wykazaliśmy, ze produkty pochodzenia mlecznego w diecie maja korzystny wpływ na zdrowie, z wyjątkiem mleka z duża zwartością tłuszczu, ponieważ zwiększa ryzyko choroby niedokrwiennej, ale co ciekawe wykazaliśmy także ze sery (+ jogurty; fermentowane produkty mleczne) maja niewielki, ale jednak ostatecznie korzystny wpływ na zdrowie. sciencedirect.com/science/ar… W najnowszym numerze @ArchMedSci mamy dwie analizy mendlowskie dotyczące ustalenia przyczynowości miedzy spożyciem sera a ryzykiem cukrzycy i osteoporozą. Okazuje się, że umiarkowane spożycie sera zmniejsza ryzyko cukrzycy typu 2 oraz ryzyko osteoporozy‼️Zapraszam do lektury! archivesofmedicalscience.com

Pewnie pamiętacie nasza analizę, która była jedna z najbadziej cytowanych w światowych mediach (@altmetric score 6280) prac w 2023 roku o roli kroków w wydłużaniu życia, w której powiedzieliśmy, ze dla osób względnie zdrowych, bez choroby sercowo-naczyniowej korzystny efekt zaczyna się od ok. 4000 kroków, z tendencją im więcej tym lepiej, z największym spadkiem śmiertelności pomiędzy 6-13 tys/dziennie‼️ Biorąc pod uwagę ogromne zainteresowanie naukowe i zdrowotne co do roli kroków na parametry zdrowotne (#stresoksydacyjny, #zapalenie, funkcja śródbłonka, #CACScore,# LDL i wiele innych), chcemy kontynuować te badania u osób zarówno z chorobami serca i innymi cywilizacyjnymi, po incydentach, ale także u tych, którzy robią średnia liczbę kroków więcej niż 👉20,000/dziennie, ponieważ nasze i inne badania nie pozwalają na wnioskowanie co do znaczenia tej liczy kroków na zdrowie (wskazują na brak dalszej korzyści zdrowotnej od 16 tys kroków). Stad jeśli bylibyście zainteresowani by wziąć udział w takich badaniach - serdecznie zapraszam i proszę o kontakt na priv. 💪

Our Expert Opinion article on the extended indications for #fenofibrate in prevention of #cardiovascular #complications, and specifically #retinopathy is a cover article of the new issue of the @ArchMedSci. This was a tremendous work of the experts representing different specializations, including preventing #cardiology, #diabetology, #endocrinology, #familymedicine, #nephrology and #ophthalmology to finally give the physicians attempt of recommendations on how to prevent retinopathy in patients with diabetes and especially how to AVOID retinopathy #complications💪 Few points to remember: 👉In 2021, 529 million people worldwide had #diabetes (average global prevalence: 6.1%). 👉By 2045 the percentage of diabetics worldwide will increase by as much as 46%. 👉Diabetic #retinopathy is one of the major complications of diabetes and is found in up to 30– 40% of patients‼️ 👉By 2045, the number of patients with diabetic retinopathy will reach 160.5 million, vision-impairing retinopathy 44.82 million and significant diabetic macular edema 28.61 million‼️ 👉Based on available data we recommend that in patients with type 2 diabetes and a diagnosis of retinopathy, the adding of fenofibrate to statin therapy is recommended to reduce the risk of retinopathy progression, the need for eye surgery and the risk of vision loss. Thanks and fingers crossed for your effective fight against #retinopathy! @PoLACongress