@KorberLab

Korber lab | Biomedical Center LMU Munich | nucleosome positioning and remodeling in yeasts | genome-wide chromatin reconstitution

 Munich, Germany
molekularbiologie.abi.med.uni-muenchen.de/ueber_uns/korber/index.html
Joined February 2021
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  • Following71
  • Followers206
3Media
Fascinated by ATP-driven chromatin remodelers? Faible for genome-wide biochemistry? Fan of reconstitutions? Check out our open PhD position in our project "Genome-wide reconstitution of chromatin dynamics" at the LMU Munich: sfb1064.med.uni-muenchen.de/… @crc_1064
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So grateful for this wonderful collaboration of hard work (@ILangstein) testing ingenious hypotheses (@alexholehouse)! Surprise: linear sequence motif(s) for specific binding may be replaced by chemical context regardless of linear sequence. Quite some leeway for IDR evolution!
Alex Holehouse@alexholehouse12 Feb 2022
I'm excited to share our new paper - an incredible multi-year collaboration with the incomparable Philipp Korber (@KorberLab) driven by one of the most impressive graduate students I've had the pleasure of working with, Iris Langstein-Skora (@ILangstein) biorxiv.org/content/10.1101/…
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KorberLab retweeted
CPRatUCPH@UCPH_CPR11 Jun 2021
We are extremely happy to announce the recruitment of @NKrietenstein as new CPR group leader starting in October. Nils will join the Protein Memory Program (headed by @groth_anja) to lead a new group focusing on the dynamics and structure of the 3D genome bit.ly/2TiMbSD

3D genome expert to establish new research group at CPR

Nils Krietenstein will join the Protein Memory Program in October to lead a new group focusing on uncovering the dynamics and structure of the 3D genome.

cpr.ku.dk
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2 papers on how chromatin remodelers, esp. INO80, process information from DNA shape/mechanics, DNA ends, barriers and other nucl. into nucl. positioning. Thanks to all involved! @Hopfnerlab @CramerLab @PetersonLab @RemoRohs @embl rdcu.be/clut1 rdcu.be/cluum
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If you still think that poly(dA:dT) depletes nucleosomes by an intrinsic mechanism in vivo, please check out our new ms, where we compile published and new evidence against this view and for an active read out mechanism by remodelers like RSC: preprints.org/manuscript/202…

The Active Rather than Intrinsic Mechanism of Nucleosome Depletion by Poly(dA:dT) Tracts

Poly(dA:dT) tracts cause nucleosome depletion in many species, e.g., at promoters and replication origins. Their intrinsic biophysical sequence properties make them stiff and unfavorable for nucleo...

preprints.org
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Since today @KorberLab is active on Twitter. Looking forward! Let's start with the two pillars of our work: why we are a lot into chromatin reconstitution and the awesome power of yeast (not just S. cerevisiae) in vivo tools... #yeast #chromatin #nucleosome #remodeling
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