T-cell activation, Super-Res Microscopy, Mechanical Forces, Immunotherapy, Traction Force Microscopy

Berlin & Zurich
Joined October 2014
Enrico Klotzsch retweeted
👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽👇🏽
We are hiring for a 2y post-doc within the @theglasgowcemi to work on on "Brillouin Microscopy of in-vitro bone marrow models to support early diagnosis of leukaemia". Get in touch if you are interested! linkedin.com/posts/massimova…
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Enrico Klotzsch retweeted
Mechanotransduction and how regulates lymphocytes in immunotherapy is what @MechanoImmunLab is presenting right now @Nano4Mech very exciting story!
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New #preprint from the lab: using the CD3-zeta gene as an integration locus to redirect T and NK cells with CARs 🎉 Great work by led by @jonas_kath! Following @j_eyquem TRAC approach, we ventured for an alternative locus suitable for more cell types. biorxiv.org/content/10.1101/…
Integration of ζ-deficient CARs into the CD3-zeta gene conveys potent cytotoxicity in T and NK cells biorxiv.org/cgi/content/shor… #bioRxiv
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Enrico Klotzsch retweeted
How is Salmonella prepared for efficient host cell invasion? Read more about the dynamic interplay between # Bacterial Flagellum and #SPI-1 during the Salmonella infection cycle in a recent work of our group @Salmo_Lab, @DoaaOsamaSaleh in #PLOSPathogens dx.plos.org/10.1371/journal.…
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Reshaping breast cancer's collagen matrix improved T cell infiltration and tumor control in mice. Could an anti-DDR1 mAb be the next weapon in our immunotherapy arsenal against solid tumors? @MechanoImmunLab & I discuss the exciting findings by Sun et al @Nature 2021.
Barring the gates to the battleground: DDR1 promotes immune exclusion in solid tumors | Signal Transduction and Targeted Therapy nature.com/articles/s41392-0…
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Point 2. Unless you are German...
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Enrico Klotzsch retweeted
FiolkaLab@FiolkaLab27 Sep 2017
Cancer cell migration imaged with isotropic subcellular resolution. Thanks to Jackson Petroll for the great rendering of our data!
Viola Vogel @Vogel_Lab, Bioingenieurin @ETH, erforscht als Einstein Visiting Fellow @BIH_Innovations @ChariteBerlin die mechanischen Kräfte in Zellen. Im Podcast teilt sie ihr Nano-Wissen wie ihre Sicht auf's große Ganze: #Pandemie, #Politik & #Forschung ➡️t1p.de/o61z
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Enrico Klotzsch retweeted
HFSP Young Investigators Enrico Klotzsch @HumboldtUni and Jonas Ries @EMBL and colleagues have developed a traction force #microscopy platform which enables the forces exerted during T-Cell activation to be measured > bit.ly/3pqj9vH
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Enrico Klotzsch retweeted
Celebrating HFSP 30 years in Tokyo with Michael Hall receiving the Nakasone prize #HFSPmtg
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Enrico Klotzsch retweeted
ELFMAL GRÜN Das sind die Gewinner: ein Überblick und eine erste Einordnung des #ExStra-Finales. #Exzellenzstrategie Jetzt im Blog: jmwiarda.de/2019/07/19/elfma…
nanobodies for super resolution imaging bit.ly/1m8efCk #NBThighlight
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On the cover this week: Three trillion and counting. Mapping tree density at a global scale
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Enrico Klotzsch retweeted
One of many amazing sights you could see along the Bondi to Coogee Coastal Walk in Sydney (via IG/Rosiebondi)
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Best travel expense form, ever! "From: Houston, To: Moon". Buzz Aldrin's travel voucher to the Moon RT@TheRealBuzz – at Munich, Bavaria
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EXTREME PAC-MAN!
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Enrico Klotzsch retweeted
ICYMI: Explore #Hubble's magnificent 1.5 billion pixel image of the #AndromedaGalaxy ab.co/1Cfeoba
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Enrico Klotzsch retweeted
A lot of problems in the world would disappear if we talked to each other instead of talking about each other.