I’m a biostatistician working in clinical trials, particularly in older adults. Most other moments I try to be on the golf course,

Winston-Salem, NC
Joined February 2012
Nicholas Pajewski retweeted
I can’t believe I’ve been selected for the Early Career Investigator Award by @AAHPM ! 🎉 A heartfelt thank you to my amazing mentors, supportive patients and families, and our dedicated palliative care team for making this possible. Feeling honored! 🙏 #AAHPM #PalliativeResearch
So proud to announce the 2025 AAHPM award winners! Your dedication to the #hapc field does not go unnoticed. Learn more about these incredible individuals and their impactful contributions here: aahpm.org/about-aahpm/awards…
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Nicholas Pajewski retweeted
Looking for a version of the MoCA that can be administered over the phone and was reminded of the Impossible MoCA, which is always fun to give to anxious colleagues. "Just a standard test I give to all my patients".
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Nicholas Pajewski retweeted
🚀 Join Yale's Cutting-Edge Brain & AI Research Team! 🧠✨ Yale's Center for Brain & Mind Health (CBMH) is hiring at all levels to lead innovative AI-driven neuroscience! We're seeking passionate researchers applying AI to brain health challenges. Don’t miss the chance to shape the future of clinical neuroscience in a highly collaborative, inclusive environment! Apply now and push the frontiers of brain science. 🌍💡 🔗 Apply here: apply.interfolio.com/157186 #AI #BrainHealth #Neuroscience #Yale #Innovation #NeuroAI #FacultyPosition #DiversityAndInclusion
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Nicholas Pajewski retweeted
NIA’s now ex-neuroscience division director falsified/fabricated study results... results that led to clinical trials of the antibody prasinezumab which had no effect on global or imaging measures of Parkinson’s disease progression in a 2022 NEJM paper science.org/content/article/…
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Nicholas Pajewski retweeted
Patients with #Alzheimers disease and #hypertension have an even greater risk of cognitive decline than those with one #riskfactor and not the other, according to a new @AlzDemJournals study led by @NeurologyYale's Adam de Havenon, MD: brnw.ch/21wMnBS
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Nicholas Pajewski retweeted
Frailty in Medicare Advantage and Traditional Medicare Beneficiaries jamanetwork.com/journals/jam…
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Nicholas Pajewski retweeted
For every study that helps us decide whether to start a new medication, there should be an equal & opposite study to help us decide when to stop a medication. With that new law of medicine, I present you this study on beta-blocker discontinuation after MI nejm.org/doi/full/10.1056/NE…
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Nicholas Pajewski retweeted
Every Target Trial Emulation Study: "Randomization was emulated using propensity score matching adjusting for baseline covariates" Narrator: this was an observational study where nothing close to randomization was done
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In my advanced CKD clinic, this is a common clinical encounter: Mr. Jones is 83 and has chronic kidney failure with a low eGFR. He’s not eligible for a transplant.
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🎓 Join Our Team! 🎓 @wakeforestmed is seeking a talented researcher for an open rank, tenure track position in Geroscience. If your work explores the biology of aging and chronic disease, we’d love to hear from you! 💼 Apply now: emis.fa.us2.oraclecloud.com/… @agingup @toddhaberkost
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Nicholas Pajewski retweeted
SPRINT showed that intensive lowering of systolic BP increased the risk of incident CKD and episodes of AKI. A study looked at legacy effect of intensive vs. standard systolic BP lowering on longer-term incidence of kidney failure. Rates of dialysis or transplantation were higher with intensive treatment, but differences were small bit.ly/JASN0459
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Nicholas Pajewski retweeted
Great work by @priyapalta
Alzheimer disease (AD)–specific biomarkers’ association with dementia starts in midlife whereas late-life measures of AD, neuronal injury, and astrogliosis biomarkers are all associated with dementia. ja.ma/4c0prth #AAIC24
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𝐖𝐚𝐧𝐭 𝐭𝐨 𝐢𝐧𝐜𝐫𝐞𝐚𝐬𝐞 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐭𝐫𝐢𝐚𝐥 𝐞𝐧𝐫𝐨𝐥𝐥𝐦𝐞𝐧𝐭? 📊 Learn how @UCSDHealth investigators consented and scheduled over 2000 clinical trial participants in less than 4 weeks (!) at low cost by integrating workflows in a vendor EHR! A short 🧵 (1/4)
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Really nice article on the importance of hypertension control. Thank you @ACPIMPhysicians for featuring our work! Continue BP control, maintain benefits | I.M. Matters from ACP immattersacp.org/archives/20…
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Nicholas Pajewski retweeted
🚨Federal claims data are critical to efforts to improve spending, quality, and equity in our health care system. In @JAMA_current, we wrote about how @CMSGov's data policy change may compromise these efforts — and recommended a better path forward. jamanetwork.com/journals/jam… 1/N
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Nicholas Pajewski retweeted
Improvement in cognitive function after kidney transplantation @KUJGKI @KUNeph @KUALZ
#Kidneydisease-related #cognitiveimpairment may improve after transplantation, according to @KUMedCenter researchers, who wrote in a study that the finding is "relevant for clinical decision-making.” bit.ly/3TmhGb4
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Nicholas Pajewski retweeted
Thank you @GeriPalBlog for the opportunity to discuss eFIs together with my wonderful colleagues @KateCallahanMD and @DaeKimMD. Check out efrailty.com - a new resource to help guide clinical frailty assessments!
Today we discuss Electronic #Frailty Indexes including various Frailty tools (i.e. eFrailty.org) as well as different definitions, metrics, & measurements. Guests @KateCallahanMD, @DrAROrkaby, @DaeKimMD. Episode bit.ly/GeriPalEp303 - hosts @AlexSmithMD | @EWidera
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ATEMPTing to navigate between “lower is better” and “less is more” – linked Comment by Nicholas M Pajewski @NMPajewski and Jordana Cohen thelancet.com/journals/lanhl…
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