PURPOSE: the Pain Research Network (@PainResearchers) header
PURPOSE: the Pain Research Network (@PainResearchers) profile picture

PURPOSE: the Pain Research Network

@PainResearchers

NIH-funded program uniting #pain #researchers across the continuum of #painresearch, from all disciplines and all career levels. https://teapawt.org/t.co/nkmStore3r

bit.ly/m/PURPOSE
Joined March 2023
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Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)Photo by PURPOSE: the Pain Research Network (@PainResearchers)
PURPOSE: the Pain Research Network retweeted
PAIN Reports (@PainReportsOPEN) profile picture
PAIN Reports@PainReportsOPENSep 28
Kaur et al. present a comprehensive synthesis of the findings from 29 studies on spinal cord stimulation. The results could serve as a valuable contribution in the spinal cord stimulation patient selection process. Learn more in #PainReports bit.ly/4dIKJ1n
Image from PAIN Reports (@PainReportsOPEN)
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PURPOSE: the Pain Research Network retweeted
Science Magazine (@ScienceMagazine) profile picture
Science Magazine
@ScienceMagazineSep 9
PET and MRI imaging found elevated levels of TSPO protein in skull bone marrow of people with chronic back pain and knee osteoarthritis compared to healthy individuals, suggesting a potential new target in understanding and treating chronic pain. Learn more in @ScienceTM: scim.ag/46IjYHa
Image from Science Magazine (@ScienceMagazine)
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PURPOSE: the Pain Research Network retweeted
Yale Psychiatry (@YalePsych) profile picture
Yale Psychiatry@YalePsychAug 21
Dr. Joao P. De Aquino of #yalepsych and @YaleMed has been awarded an R01 grant to build a human laboratory model of how alcohol affects pain in people living with alcohol use disorder (AUD), chronic pain, or both. bit.ly/4xS8ZGP
De Aquino Awarded NIH R01 Grant to Study How Alcohol Shapes Pain in Co-Occurring Alcohol Use...

De Aquino Awarded NIH R01 Grant to Study How Alcohol Shapes Pain in Co-Occurring Alcohol Use...

Joao P. De Aquino, MD, assistant professor of psychiatry, has been awarded an R01 grant to build a human laboratory model of how alcohol affects pain in people

medicine.yale.edu
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PURPOSE: the Pain Research Network retweeted
tor wager (@torwager) profile picture
tor wager
@torwagerAug 6
Human brain stimulation activates cell assemblies and transcriptional pathways linked to neuroplasticity. Wow!
Stefano Berto, PhD (@StefanoBerto83) profile pictureStefano Berto, PhD@StefanoBerto83Aug 5
Some super cool news of the day: my name is on a @Nature paper for the first time!! This work grew out of a collaboration with my AMAZING postdoctoral mentor, Genevieve Konopka @KonopkaLab, and neurosurgeon Bradley Lega at UTSW. 👇 nature.com/articles/s41586-0…
Stimulation modulates gene-linked cell assemblies in the human brain

Stimulation modulates gene-linked cell assemblies in the human brain

Nature - Stimulation of human cortex reorganizes neural assemblies and induces cell-type-specific gene regulatory programs, establishing an ex vivo framework that links stimulation parameters to...

nature.com
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PURPOSE: the Pain Research Network retweeted
tor wager (@torwager) profile picture
tor wager
@torwagerJun 24
scikit-learn inspired predictive modeling in canlab_core

scikit-learn inspired predictive modeling in canlab_core

Article · @torwager
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PURPOSE: the Pain Research Network retweeted
WashU Medicine Anesthesiology Research (@WashUAnesRsrch) profile picture
WashU Medicine Anesthesiology Research@WashUAnesRsrchAug 7
How does childhood trauma shape the brain? New research from @washumedicine and @PrincetonNeuro reveals how early-life stress can leave a lasting imprint on the brain, increasing vulnerability to stress later in life. @Meaghan_Creed @WashUPain medicine.washu.edu/news/how-…

How early-life stress leaves a ‘scar’ inside brain cells | WashU Medicine

A mouse study finds changes to DNA packaging form a molecular memory of trauma, making the brain vulnerable to future stress.

medicine.washu.edu
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PURPOSE: the Pain Research Network retweeted
Faraz Arkam (@farazrkm3) profile picture
Faraz Arkam@farazrkm3Jun 2
Congratulations @salimyakdan!! Really exciting work being done at the @JGreenberg_MD lab!
WashU Med Taylor Family Department of Neurosurgery (@WashUNeurosurg) profile pictureWashU Med Taylor Family Department of Neurosurgery@WashUNeurosurgJun 1
Research from the Greenberg Lab has been featured in the All of Us Research Highlights series. Led by Salim Yakdan, MD, MSCI, the study found that higher physical activity levels were associated with a lower risk of future neck, low back, and hip pain. allofus.nih.gov/article/all-…
Image from WashU Med Taylor Family Department of Neurosurgery (@WashUNeurosurg)
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PURPOSE: the Pain Research Network retweeted
Andrea Polli (@LANdreaSS) profile picture
Andrea Polli@LANdreaSSJul 27
Our latest paper: "Clinical applications of epigenetic signatures in chronic pain management and health outcome prediction" - is now free access for the first 50 downloads using the link below, enjoy! tandfonline.com/eprint/NCNZI…
Image from Andrea Polli (@LANdreaSS)
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PURPOSE: the Pain Research Network retweeted
NYU Pain Research Center (@NYUPainResearch) profile picture
NYU Pain Research Center@NYUPainResearchJul 14
NEW PRC PAPER 🚨: The Jensen lab discovered that disrupting synaptic vesicle recycling via AAK1, Dnm1, and Dnm3 targets chronic itch at its source. Amazing work @Circle_J_Labs @PazDurn @tonello_raquel! frontiersin.org/journals/mol…
Frontiers | The contribution of endocytic mediators to itch transmission

Frontiers | The contribution of endocytic mediators to itch transmission

IntroductionChronic itch is a major burden, impacting the quality of life for one in four adults, and is closely associated with increased levels of anxiety,...

frontiersin.org
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PURPOSE: the Pain Research Network retweeted
Geoffroy Laumet (@GeoffroyLaumet) profile picture
Geoffroy Laumet@GeoffroyLaumetJun 26
Monocyte-Derived IL-10 Drives Sex Differences in Pain Duration #neuroimmunology @PainResearchers July 15, 2026 2:00 PM - 3:00 PM ET / 11:00 AM- 12:00 PM PT zoom.us/j/99145958564?pwd=Nb… Read the abstract: painresearchers.com/news/114…
Image from Geoffroy Laumet (@GeoffroyLaumet)
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PURPOSE: the Pain Research Network retweeted
Tao (@TaoChelab) profile picture
Tao@TaoChelabJun 22
Glad to share our recent work showing the structures of ketamine bound to opioid receptors! Another great teamwork. Congrats Qianru Jiang, Jianming Han and EJ Fine. @NatureSMB rdcu.be/fpLRM
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PAIN Journal (@PAINthejournal) profile picture
PAIN Journal@PAINthejournalJun 8
Replying to @GeoffroyLaumet
@GeoffroyLaumet et al. find that CCL12 is upregulated after incision, directly sensitizes nociceptors, and its neutralization alleviates postoperative pain and prevents hyperalgesic priming, identifying a novel therapeutic target. Learn more in #PAIN bit.ly/4eUo849
Image from PAIN Journal (@PAINthejournal)
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Stanford Pain Medicine (@StanfordPain) profile picture
Stanford Pain Medicine
@StanfordPainJun 5
Chronic pain conditions affect 24% of the US population and account for the greatest cause of disability. In 2024, the @NIH convened a working group of pain researchers and clinicians, including @TawfikLab, to help shape the next five years of pain research funding through the HEAL Initiative. The result was a new report outlining 10 priorities for the future of pain medicine. The authors note that these recommendations are intended to invite further active discussion across the pain research community. What do you think of the 10 priorities? Full report: bit.ly/4xd3K56
Image from Stanford Pain Medicine (@StanfordPain)
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Neuropsychopharmacology (@npp_journal) profile picture
Neuropsychopharmacology@npp_journalMay 29
This recent study demonstrated in Triazole 187, a biased KOR agonist, could potentially treat chronic itch and anxiety with minimal side effects in a 🐀 model nature.com/articles/s41386-0…
Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic...

Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic...

Neuropsychopharmacology - Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic-like behaviors in mice

nature.com
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PURPOSE: the Pain Research Network retweeted
NIH-DoD-VA Pain Management Collaboratory (@painmc3) profile picture
NIH-DoD-VA Pain Management Collaboratory@painmc3May 29
🗣️Drs. Karen Seal & Will Becker were interviewed by Serena Crawford; Assistant Director of Communications @YaleMed about their recent wHOPE study results being published in @JAMA_current. Check out the interview here: tinyurl.com/bdmjra83 @VAResearch @NIH_NCCIH #painresearch
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PURPOSE: the Pain Research Network retweeted
Waggoner Lab (@LabWaggoner) profile picture
Waggoner Lab@LabWaggonerMay 28
A longitudinal atlas of human psoriatic skin reveals the mechanisms of anti-IL-23 therapy in disrupting the type 17 inflammatory circuit @ImmunityCP @joigud @UMich cell.com/immunity/fulltext/S…
Image from Waggoner Lab (@LabWaggoner)
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Waggoner Lab (@LabWaggoner) profile picture
Waggoner Lab@LabWaggonerMay 28
In a mouse model of #NF1, nerve-ensheathing Schwann cells produced and released more of the neurotrophic factor GDNF, which activated peripheral sensory neurons, heightening their sensitivity to touch @scisignal @JankowskiLab @CincyResearch science.org/doi/10.1126/scis… @NamrataGRRaut
Image from Waggoner Lab (@LabWaggoner)
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NYU Pain Research Center (@NYUPainResearch) profile picture
NYU Pain Research Center@NYUPainResearchMay 22
Exciting new preprint from the Russo Lab at University of Iowa! Blocking α1‑noradrenergic signaling restores glymphatic flow and reverses migraine‑like allodynia in mice. buff.ly/OIEnvsY
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NYU Pain Research Center (@NYUPainResearch) profile picture
NYU Pain Research Center@NYUPainResearchMay 28
Amazing day so far at the PRC symposium! So much exciting science from our research community and awesome keynote speakers. @karagm2009 @SarahANajjar @tonello_raquel @PazDurn @mariafpessano @ElisaDamo95 @LinYungHung1 @Horemheb25
Image from NYU Pain Research Center (@NYUPainResearch)
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PAIN Journal (@PAINthejournal) profile picture
PAIN Journal@PAINthejournalMay 29
In this week’s #PAIN Featured Image, @camille_fauchon et al. depict how baby cries encode graded pain signals through acoustic features like pitch and vocal roughness, which listeners decoded to assess infant pain severity. Learn more at bit.ly/4n4Gx0i
Image from PAIN Journal (@PAINthejournal)
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