Ph.D. student @weillcornellgs @mskcancercenter | prev @insitubiology @broadinstitute | B.S. @texasscience
New York, NY
Joined February 2022
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Thrilled to be starting my PhD in the BCMB program at @WeillCornellGS this fall! Grateful for the incredible mentorship at @insitubiology (@immunoliugy, @hattaca, @AndyRusss + others) and @TexasScience; couldn't have done it without their support. Excited for the journey ahead!
Ruth Raichur retweeted
It’s finally out out!!!!!! What a journey it has been!!! I have learned so much from all the incredible people that made this possible!
How does aging reshape a tissue that must continually rebuild itself hundreds of times?
Using spatial transcriptomics, we find that ovarian aging disrupts the coordination of cells across space and time before reproductive cycles stop.
#OvarianAging
Ruth Raichur retweeted
🗞️Our June issue is live!✨Read about the healthspan and lifespan effects of time-restricted feeding in mice, insights from mathematical models of aging, how R-loops drive the SASP, & much more nature.com/nataging/volumes/…
Ruth Raichur retweeted
Thrilled to share our newest method for transcriptome recording using TimeVault!
science.org/doi/10.1126/scie…
Ruth Raichur retweeted
"Rizz-ard of Oz: There's no place like lab"!
Thanks @genomics212 for the annual halloween party!
Ruth Raichur retweeted
TissueMosaic, our method to study how changes in tissue structure across conditions affect cell-intrinsic function, is now out @CellSystemsCP!
cell.com/cell-systems/fullte…
Ruth Raichur retweeted
Check out our new method of spatial transcriptomics with computational reconstruction on @NatureBiotech. Make spatial transcriptomics easier and more accessible.
idp.nature.com/authorize?res…
Ruth Raichur retweeted
1/ Thrilled to share an advancement in gene therapy from my PhD in @NatureComms! We've developed a new approach to reduce immune responses while maintaining efficiency—paving the way for safer, more effective therapies. Big thanks to @zhangf & @mircoscopy! bit.ly/redicas9
Grateful to have been included in this incredible project, alongside such an amazing team!
Excited to share our lab's first preprint: we used spatial transcriptomics to dissect how aging disrupts the cycling ovary! 🧵
This was an incredible team effort w/ @jenngarrison @Tammyinlab @davidsebfischer AlisonKochersberger @RuthRaichur @sophiamszady
Ruth Raichur retweeted
We are excited to publish a spatially resolved single-cell multi-omic census of the placenta, contributing to the @humancellatlas project. The placenta plays an essential role in maintaining a healthy pregnancy, yet its function remains poorly understood. nature.com/articles/s41591-0…
Ruth Raichur retweeted
We’re excited to share our latest computational method, TissueMosaic, for comparative analysis of spatial transcriptomic datasets across conditions! (1/5)
biorxiv.org/content/10.1101/…
Ruth Raichur retweeted
Pretty normal Thursday in the lab ...
#placentasinspace #placentasinorbit #reproductiveimmunologyonthemoon
Thank you @genomics212 for the fun party!
Ruth Raichur retweeted
Check out this awesome new spatial lineage tracing paper from @MattG_Jones @sundakao @dianyang1117! One of the coolest uses of Slide-tags yet. Was a pleasure to help out.
I'm thrilled to share our new study of the spatial evolution of Kras;p53-driven mouse lung adenocarcinoma! It's been fantastic leading this with @dianyang1117 & @sundakao, and enjoying a long-standing collaboration with @JswLab @YosefLab & @insitubiology. biorxiv.org/cgi/content/shor…
Ruth Raichur retweeted
Our paper on continuous mutagenesis in living cells using HACE is now out in @ScienceMagazine!
We now demonstrate that HACE continuously generates mutations over a 10-day period and enables targeting using dCas9 without introducing DNA nicks.
science.org/doi/10.1126/scie…
Ruth Raichur retweeted
New review & podcast alert! Our latest review in @AnnualReviews delves into maternal B cell tolerance to the placenta & fetus. Check it out here:
annualreviews.org/content/jo…
(1/4)
Ruth Raichur retweeted
7 years ago, I met a junior fellow named @JD_Buenrostro who blew me away with a vision of futuristic genomic technologies
Today, we (@ajaylabade31, @carolinecomenho) are excited to share our first steps into that future: Expansion in situ genome sequencing
1/
Ruth Raichur retweeted
With reconstruction, we can do Slide-seq/Slide-tags at higher throughput and larger scale. We applied it to a 1.2 cm P1 mouse section and UMAP learns the manifold over iterations.
Ruth Raichur retweeted
Kamala's mother immigrated from India to pursue a PhD & stayed to work as a cancer researcher
Kamala's father immigrated from Jamaica to pursue a PhD & stayed to work as a professor
Immigrant scientists contribute not only to science but to society at large -- for generations
Ruth Raichur retweeted
On the International Day of Women and Girls in Science, let’s help girls everywhere pursue careers in science, technology, engineering and math. Our world is better with their ideas and perspectives.
Ruth Raichur retweeted
We are happy to share our latest long-range, programmable mutagenesis toolbox - the Helicase-Assisted Continous Editing (HACE) system - to achieve target-specific mutagenesis of the endogenous genome. (1/11)
biorxiv.org/content/10.1101/…
