@WeiTaoLab

Philip Yeo Chair Professor in Medicine @NUSMedicine | Member of Academia Europaea (MAE) | AIMBE Fellow

 Singapore
weitaolab.com/
Joined April 2019
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Thanks @NatureMedicine for this interview, and I am glad that the Drug Delivery Technologies developed in my lab can be highlighted. It is also my great honor to be alongside world's top scientists - Profs. Bob Langer, @SMitragotri, @ryanfdonnelly, etc. nature.com/articles/s41591-0…
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A new chapter begins. After wonderful years @BrighamWomens & @harvardmed, I'm honored to move to @NUSMedicine as the Philip Yeo Chair Professor in Medicine and Tenured Full Professor of Pharmacology. medicine.nus.edu.sg/medphc/n…

Welcome and Congratulation to Professor TAO Wei - Pharmacology

NUS Department of Pharmacology warmly welcomes Professor TAO Wei to the department and congratulates him on his prestigious appointment as Philip Yeo Chair Professor in Medicine. Professor TAO joins...

medicine.nus.edu.sg
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I also can't wait to build something meaningful here with an exceptional community. The best is yet to come.🧬🇸🇬 Grateful for the past, excited for the future.🙏
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Sprayable Lactococcus lactis-Nanocatalyst Gel for Postsurgical Immunomodulation in Preclinical Oral Squamous Cell Carcinoma | Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…

Sprayable Lactococcus lactis-Nanocatalyst Gel for Postsurgical Immunomodulation in Preclinical Oral...

Abstract. Oral squamous cell carcinoma (OSCC) is one of the most prevalent and aggressive head and neck cancers. Emerging evidence shows that distinct micr

pubs.acs.org
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Thrilled to share our latest @natrevbioeng paper with Profs. Bob Langer @MIT, Gaurav Gaiha @ragoninstitute, et al. In this Review, we evaluate clinical trials of HIV mRNA medicine and discuss persistent challenges in developing mRNA-based interventions against HIV. @harvardmed
Nature Reviews Bioengineering@natrevbioengJan 10
mRNA technology for the prevention and treatment of HIV-1 infection dlvr.it/TQG89r
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We are delighted to announce that our article has been selected for the front cover feature in the 2026 First Issue of American Scientist!👉 "Messenger RNA Can Do More for Medicine" shar.es/agK6Yq @XiangangHuang @MGBResearchNews @harvardmed
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This integrative approach represents a notable advance in LNP characterization, offering a more mechanistic understanding of how structural and biophysical attributes influence functional performance. - Another fantastic work by @MJMitchell_Lab and his team! @NatureBiotech
Nature Biotechnology
@NatureBiotech29 Oct 2025
Replying to @NatureBiotech
Research Briefing: Solution biophysics reveals the polydisperse structure of RNA lipid nanoparticles go.nature.com/47Mquhs rdcu.be/eNlNL
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New in @NatureNano: Systemic delivery of IL-10-mRNA NPs triggers strong immune surveillance in diverse tumor models. This #mRNA NP strategy may offer promise for overcoming recombinant IL-10's challenges in immunosuppressive tumors. nature.com/articles/s41565-0…
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Full text link: rdcu.be/eAcNi
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statnews.com/2025/07/16/scie…

Scientists show that mRNA therapy can be delivered as a capsule

Researchers used a capsule engineered to prevent stomach acids from degrading liquid mRNA therapy to treat inflammatory bowel disease.

statnews.com
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RNACap can orally deliver liquid mRNA therapeutics to the intestines in response to intestinal pH, the resulting pressure release, and contractions science.org/doi/10.1126/scit… @ScienceTM
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The new issue of #ScienceTranslationalMedicine has arrived! Engineered capsules can deliver liquid mRNA therapeutics to treat intestinal disease in animals, the complement cascade offers a target in acute chest syndrome in sickle cell disease, and more. scim.ag/44Ut82f
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Our new paper is published as a Cover Story -"Eating the Message" in @ScienceTM. This paper demonstrates that oral mRNA delivery to the intestines is feasible using our RNACap design. Congrats to our Rising Star @XiangangHuang and the team!
Science Translational Medicine@ScienceTM17 Jul 2025
Engineered “RNACaps” provide oral delivery of liquid #mRNA therapeutics to the intestines in small and large animals for the treatment of #colitis and could support the clinical translation of oral mRNA therapies. @WeiTaoLab @BrighamAnes @XiangangHuang scim.ag/3IwtODi
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By loading different types of mRNAs, new oral mRNA vaccines for infectious diseases and oral mRNA medicines for cancers are possible. This technology could also benefit the oral delivery of other types of biologics (e.g., nucleic acids and proteins) to tackle different diseases.
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New Issue Online👏 | Volume 6 Issue 6🥳 check👉onlinelibrary.wiley.com/toc/… @BenZhongTANG1 @yuning_hong @NusXie @shrikezhang @mcgonigalgroup @Alc_Rimbaud @RivardGroupUofA @WeiTaoLab @akyetisen

Aggregate: Vol 6, No 6

Click on the title to browse this issue

onlinelibrary.wiley.com
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Happy to share our most recent article on using RNA therapeutics to promote healthy aging @NatureAging. Congrats to Shuying and Qian from my team. Link here: nature.com/articles/s43587-0…
Nature Aging@NatureAging11 Jun 2025
Online now! ✨Chen et al review RNA therapies targeting mechanisms of aging and age-related diseases nature.com/articles/s43587-0… rdcu.be/equCC

Using RNA therapeutics to promote healthy aging

Nature Aging - Chen and colleagues explore how RNA therapeutics targeting mechanisms of aging can be used to treat age-related diseases and promote healthy aging. They discuss current preclinical...

nature.com
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The Tao Lab currently has one postdoc position opening. More information can be found on the page below: weitaolab.com/openings
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Modulating nano-bio interface via drug-framework hybridization to activate chemoimmunotherapy against glioma postoperative recurrence dlvr.it/TJx2mp #biomaterials #bioengineering
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Happy to see our invited Perspective on "Live bacterial chemistry in biomedicine" online @Chem_CP Congrats to Senfeng and Qimanguli in my team @BrighamWomens @harvardmed cell.com/chem/abstract/S2451… Free access here: authors.elsevier.com/a/1ktHw…

Live bacterial chemistry in biomedicine

This perspective summarizes the programmable chemical sites on live bacteria and the potential physical, chemical, or biological functions achievable through chemical engineering strategies, highli...

cell.com
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Honored to be inducted as a Fellow into the American Institute for Medical and Biological Engineering @aimbe @BrighamWomens @harvardmed! Many thanks to my nominator, who is my real role model in many aspects! (Thanks to my friends for taking nice photos from different angles📸)
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