Pradeep Gowda retweeted
I don't think people realise how big a deal this is.
If you have cancer, or somebody you know has cancer, there is a company in Hyderabad that wants to build a personalised cancer vaccine for you.
Try approaching any big pharma company and asking for a personal vaccine. If they even reply to your email, this is the response you'll get: we don't do that here.
PopVax, on the other hand, takes your tumour sequencing data (or a sequence you've designed), designs candidate neoantigen vaccine sequences with their AI pipeline, produces the mRNA, encapsulates it in their LNP formulation, fills vials, and runs QC, all in 8 to 10 weeks. They’re publicly committing to capacity for 100+ of these over the next 12 months and asking people to email them their cancer type/stage and sequencing details.
What a time to be alive.
You can use grok bot, I just download the transcript to my Obsidian using this souped up Go program using Granola's API github.com/pradeep-stellar/g…
$ go install github.com/pradeep-stellar/g…
I tried using Soniox on a @svat's recommendation, & it is pretty awesome.
Typing at the speed of speech, and it is quite forgiving. I thought certain "foreign" words would require enunciation. It is quite forgiving though.
(reading aloud Prof SKR's book on Bodhidharma)
Replying to @svat
Pretty impressive.. it even got the original em-dash in the text correctly (only a small pat for myself for conveying that in speech :p)
Thank you! this is great.
Street dogs in Maharashtra are the most respectful.
Always calling you "bhau bhau" while running behind you.
Serendipity!
Putting a "manager/ponytail/supervisor" node that monitors requests made by agents in sandboxes is how I was thinking of forcing/ensuring "correct behavior" .. in shower today.
Ever since i put in egress proxy into Kaas, I've been intrigued by this approach.
One of the biggest challenges I’ve grappled with lately is how to create determinism where it otherwise doesn’t exist. How do I get an agent to behave like I would, without me telling it to?
cra.mr/a-little-determinism
Replying to @svat
Pretty impressive.. it even got the original em-dash in the text correctly (only a small pat for myself for conveying that in speech :p)
Thank you! this is great.
Replying to @Krishna_rm
this is not translation. but speech (voice) to text.
Elevenlabs' Kannada Speech to Text is pretty good.
I'm considering using this to transcribe text when OCR fails.
My personal favorite of clever phrasing in Indian road safety messages - "ati vega, tithi bega" (higher speed, quicker funeral).
The rhyme only works in Kannada, ofc... but it tickles me every time I read it.
(below, BRO = Border Roads Organisation)
My recent project - an easy to browse, and read library of late Prof S K Ramachandra Rao's published Kannada and English works:
files.btbytes.com/profskr/in…
And wrote up the process on my blog: maxim.usindic.us/2026/10/30/…
thank god for AI, this was so toxic dontasktoask.com/
Pradeep Gowda retweeted
When people talk about that "old-school theatre" acting vibe, what they really mean is that these performers learned their trade the hard way, treading the boards night after night in repertory companies.
Actors such as Patrick Stewart and Brian Blessed both came out of working-class Yorkshire families - Stewart the son of a textile worker, Blessed of a coal miner - while others like Anthony Hopkins, from a baker's household in industrial Port Talbot, Albert Finney from a northern working-class background, and Ian McKellen - despite going to Cambridge - from the mill towns of Lancashire, spent years in regional rep theatres taking on every kind of role and refining their craft under real pressure before anything like fame arrived.
For many of them the Royal Shakespeare Company then offered a further proving ground, giving them major classical stages on which to display the authority and technical command they had already built up over years of weekly rep. That long, grounded apprenticeship is what produced the presence that later carried so well into both London West End theatre, television, and film.
It stands in sharp contrast to so many of today's instant stars, who tend to come from more comfortable middle-class backgrounds, leave drama school, and move almost straight into television or film stardom without that same prolonged period of learning by doing on the boards.
Replying to @hsraghav @shashikiran_bn
I found the links on that page not very helpful for reading, so I put them up here:
files.btbytes.com/profskr/in…
with a note on what I did maxim.usindic.us/2026/10/30/…
HTH



























