We have known about #WPW and accessory pathways as a common cause of SVT for >100 years and have effective procedures to address them, but we still have NO IDEA why some patients are born with these extra slivers of muscle that electrically connect atria to ventricles. Medicinal use of lithium in pregnant women leads to heightened risk of a particular form of congenital heart disease associated with these pathways. Might variable levels of lithium in drinking water affect the chance a growing fetus will be born with such a pathway? @jclinicalinvest @UCSF @UCSFHospitals @stopafib @DrDave01 @KnowYourPulse JCI - Elevated lithium levels in drinking water are associated with higher prevalence of Wolff-Parkinson-White diagnoses jci.org/articles/view/205020

Cardiac Electrophysiology at a Crossroads: Building on Dr. Josephson's 20 years of observations. Is EP science, procedure or both? What is the future of EP science? authors.elsevier.com/a/1nzSl… #EPeeps #CardioX @ACCinTouch @HRSonline

‼️ Now online in the #EHJ @ESC_Journals: The Vasc-PFA study 📖 academic.oup.com/eurheartj/a… @ehj_ed Our study provides important insights into the acute coronary vascular effects of monopolar biphasic #PulsedFieldAblation 🔬 Key findings: 👉 Acute, localized endothelial dysfunction occurs following coronary exposure to PFA, while vascular smooth muscle function remains preserved. 👉 The effects are site-dependent: endothelial dysfunction was least pronounced after cavotricuspid isthmus (CTI) ablation and most evident following great cardiac vein (GCV) and epicardial PFA. 👉 Selective endothelial injury with preserved smooth muscle cell function may explain the observed vasomotor dysfunction and why nitroglycerin can rapidly reverse clinically apparent coronary spasm despite persistent endothelial impairment. 📌 Why does this matter? Anatomical factors may influence electric field delivery and the degree of coronary exposure. The findings also raise important questions about the potential relationship between acute endothelial injury and delayed coronary complications, including myocardial ischaemia, ventricular arrhythmias, and longer-term vascular remodelling. #PulsedFieldAblation #Electrophysiology #CardiacElectrophysiology #Cardiology #CoronaryArteries #Arrhythmia #CardiacResearch @drjohnm @DrJasonAndrade @TinaBaykaner @DrRoderickTung @ftrae @peterkistler3 @ivroca @shivkumarmd @LuigiDiBiaseMD @nmarrouche @S_NarayanMD @Dr_Santangeli @atulverma_md @SCYap77 @VivekReddyMD @MoritzNies @jskoruth @arnelasaljic @DalgasSarah @PrashSanders @harry_crijns @Elliott_AD @kvernooy @Ed_Gerst @True_EP @Drdevignair @Mel_Gunawardene @jongichun @RolandTilz @Phiso_de lnkd.in/p/eNvPWUK9

Less than 2/3 of patients with atrial fib and elevated stroke risk prescribed oral anticoagulants at baseline, 12.5% were added in the year after diagnosis. @CircOutcomes ahajournals.org/doi/10.1161/…

Vinny Mauri is one of the coolest stories in sports right now. He is already one of the fastest American marathon runners ever, yet he's run only two marathons, doesn't have a coach, and usually trains indoors on a treadmill at Planet Fitness.

Blinded withdrawal of randomized treatment with low-dose digoxin or placebo in heart failure: the DECISION trial academic.oup.com/eurheartj/a… #digoxin #heartfailure via @ESC_Journals

Meet Miguel Rojas. He studied all 100 citizenship questions. He wanted no special treatment because he’s a professional baseball player. And when he passed, he said he was prouder of that perfect score than his World Series home run. What stood out to me most was his gratitude. He talked about America opening its doors to him 21 years ago and said he’s never taken that opportunity for granted. Preparation. Respect for the process. Gratitude for the country that gave you an opportunity. Wanting to contribute and be judged by your character, not your status.

I know both and I know both care about evidence. it is also refreshing to even see a conversation about evidence without political theater of left vs right. every sensible person should appreciate how low the risks are. current covid hospitalizations are probably an overestimate since covid->pneumonia/hypoxia->hospitalization is a zebra now. so covid hospitalizations are a mix of incidental or mild and unrelated versus the now most common causal path of covid>URI>volume depletion/fatigue> fall or syncope. so if you can mitigate that, that could be helpful I also don't believe that VA group or their prior work. Have they been right about anything? wrong on long covid, wrong on repeat infections, wrong on glps helping every outcome (cognitive, psychiatric). so I don't have faith in this one as our main evidence we just ultimately have no idea and people have to make decisions nonetheless. i think the risks are going to be tiny/rare on either side. I personally wouldn't recommend it in 1st, 2nd, or third trimester. good read nonetheless

I predict that AVR with TAVR removal will become the new CABG on previously stented patients and the number of surgical AVR will re-surge in the years to come. However, the outcomes will worsen because of technical challenges and surgeons’ lack of open training.