A tube within a tube. Co-founder & COO @ResearchHub

Washington, DC
Joined April 2017
Patrick Joyce retweeted
The Ross Prize at Feinstein Institutes @NorthwellHealth is an incredibly prestigious prize that rewards fundamental work that led to real breakthroughs for patients? Who do you think should be nominated this coming year? molecularmedicine.submittabl…
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Patrick Joyce retweeted
If you’re working on hair loss research, we’d love your input on our latest funding call at @ResearchHub! Join the discussion, share your ideas, and help shape what gets funded. researchhub.com/grant/33066/…
JUST IN: Veradermics announces its experimental hair-loss pill significantly increased hair growth in over 500 men, with no serious side effects reported in a late-stage study.
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The results are in! Peer review relies on people giving their time. How often do we ask reviewers how the system should work for them? We’ve published the findings of the Pirevios reviewer survey, based on 200+ completed responses. Among those who responded: • 71% had considered stopping reviewing in the past year. • 58% named time demands as their main reason for declining a review. • 73% selected payment or compensation as one possible improvement. • 73% said they had never been asked how peer review should work. This was a self-selected survey, so these figures do not represent all reviewers. The full report includes detailed charts, written-response themes and methods: pirevios.com/survey-report The findings are helping shape what we’re building at Pirevios: a directory where reviewers can describe their specialities and availability, and say whether they are open to unpaid, paid or hybrid reviewing. Our aim is to help journals find suitable reviewers sooner, reduce invitations that do not fit, and give more reviewers a chance to contribute without repeatedly approaching the same people. Thank you to everyone who shared their experience. I’d welcome your thoughts on how we can make this genuinely useful for reviewers and journals. More about Pirevios: pirevios.com/ @mirvatalasnag @sbrugaletta @ncurzen @mmamas1973 @gbiondizoccai @AnilMakam @dr_yakupergun @EslamAbady33 @francisdeng @PTarantinoMD @ross_prager @LocasaleLab @DrNeilStone @drjohnm @DrDamluji @wisit661 @Hemida_MD @BrettSperryMD @docmartin22 @JadAbdelsattar @Azeem_Majeed @Dr_AmerZeidan @DrToddLee @doctorinigo @AmitGoyalMD @acorderofort @Elsayed_saidx @jtsaxon
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Patrick Joyce retweeted
I feel caught by the idea that idea generation is not the true bottleneck for biological research. AI can help us reason and create hypotheses and simulations at a tremendous scale. But, until we get to a point where actually doing the biological experiments is as easy, (and probably widespread) we won't see a difference in wet-lab based work. Biology still requires time and is extremely variable as a function of itself. It is hard to simulate correctly, especially at the level of an organism. The comparison right now is a plant growing to a snails pace.
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Our fifth annual SciCon is coming to San Francisco on December 10. An invite-only gathering of funders, researchers, and AI in science leaders for a day on how research gets funded, evaluated, and replicated. Invitations are going out now. Keynote announcement coming soon.
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Be there or be square
11-17-26... Austin, Texas IMAX premier. dmtquest2.org
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Deposit your base:0xfbb75a59193a3525a8825bebe7d4b56899e2f7e1 on ResearchHub, earn ~31% annualized yield in Funding Credits, and use them to fund research proposals. Join 584 holders already earning: researchhub.com/endowment
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Patrick Joyce retweeted
Today, we are thrilled to unveil Quantum Life Technologies (QLT). While we are not sharing specifics and are a for-profit focused lab, our mission is to fundamentally change the way in which AI software and hardware are delivered to increase the computational capability and computational efficiency (simultaneously) by many orders of magnitude by learning from nature and biology. Learn more here. We are hiring ! I’m incredible honored to be joined by my co-founders @StuartHameroff and Jack Tuszynski as well as our founding scientists @DanielLanino and @natashacg14. 🙇🏻‍♂️ qlt.inc/
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They don’t even know crypto is fixing science
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Patrick Joyce retweeted
Exciting to hear progressive funding and metascience entering the zeitgeist. @patrickc on why science needs new models: • ~78% of fast grant recipients would change their research agenda a lot (most to make it more ambitious) if they could just spend existing grant money freely. A commentary on incrementalism vs bold innovations. • NIH funding has inverted where <40 year olds now get only ~22% of what >50 year old researchers receive (was 1.7× more in 1980). Fund younger PIs! Most Nobel Prize winners did their work in their 30s and 40s. • Arc’s origin: a 2.5-year estimated NIH grant cycle + CRISPR work largely passed over by NIH. Highlighting a case for faster, more flexible, curiosity-driven institutions.
My full fireside conversation with @patrickc at the Science: A New Golden Age Summit. We discussed building new institutions for discovery, accelerating scientific progress, and how America can move faster on the hardest scientific challenges.
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Patrick Joyce retweeted
Ferromagnetic material turned up in 74 of 96 bee species tested, across all six families sampled, and in some wasps and flies too. It tracked body size, not ancestry (whole-body magnetometry, 138 bees; no behavioral tests). xitter.cf/niroshajmurugan/status…
Bees are magnetic. But are social bees more magnetic? Such a cool @ScienceMagazine paper looked across 96 bee species and found something unexpected: magnetic properties varied with social behavior. Eusocial bees showed stronger signatures in some measures of ferromagnetism than solitary bees. Even more interesting, magnetoreception appears to predate bees altogether, suggesting evolution may have tuned an ancient sensory system differently as species became more social. A beautiful example of how a physical property of an organism might intersect with collective behavior. Full read here: science.org/doi/10.1126/scia…
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Patrick Joyce retweeted
We have a decision: “Microplastics in brains” will be a new funding opportunity in the near future on @ResearchHub
Which of these viral topics would you most like to see @ResearchHub fund next? These topics all got a lot of media attention recently, but much of the science behind them is still unknown! More background on each one in the thread below 👇
35%Microplastics in brains
15%Cat parasite & behavior
24%Young blood & aging
26%Spaceflight & the body
34 votes • Final results
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One of the most exciting RFPs on @ResearchHub to date! $150K to figure out what was actually in the sky in 1950. High quality truth seekingnegative results win the same prizes as positive ones. Props to @DrBeaVillarroel and @TylerDiorio on this one 💫🔭
Project Lost Light invites professional scientists, citizen scientists, and students from around the world to participate in a challenge to replicate -- or challenge -- pre-Sputnik transient studies using historical (pre-Sputnik) photographic plate collections from around the world. First prize: $75,000 Second prize: $50,000 Third prize: $25,000 The competition accepts data from all pre-Sputnik photographic plate collections, except those from Palomar Observatory. Learn how to detect transients, search for transient hotspots, investigate possible correlations with documented nuclear tests, and see where your own methods take you! Are we alone on Earth, or are we witnessing the presence of another civilization? Stop waiting for governments, UAP committees, or presidents to give you the answer -- go out and find it yourself. The competition is open to individuals and teams who have not previously published research on pre-Sputnik transients. The competition is hosted and independently organized by Research Hub: researchhub.com/grant/32931/… Read more on: lostlightproject.netlify.app… @TylerDiorio @ResearchHub @BrianDoher37387 @BrianMuraresku
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Patrick Joyce retweeted
The @ResearchHubF used our new AI assistant to: → Draft an RFP focused on hair loss research → Generate proposals in response to the RFP Now, they're inviting the community to review, comment on, and refine the proposals. researchhub.com/grant/33066/…
>Create a new AI assistant >Generate AI proposals >Incentivize experts to curate & refine >Refined proposals can get funded >Experts get sourced to execute Where AI proposals get refined, funded, then matched to scientists to execute.
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Patrick Joyce retweeted
In mouse striatal slices, astrocyte-targeted AMPAR blockade caused activity-dependent synaptic depression. AstroHTP adapts DART for astrocyte-specific pharmacology; the exact coagonist signal remains unresolved. biorxiv.org/content/10.64898…
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Project Lost Light invites professional scientists, citizen scientists, and students from around the world to participate in a challenge to replicate -- or challenge -- pre-Sputnik transient studies using historical (pre-Sputnik) photographic plate collections from around the world. First prize: $75,000 Second prize: $50,000 Third prize: $25,000 The competition accepts data from all pre-Sputnik photographic plate collections, except those from Palomar Observatory. Learn how to detect transients, search for transient hotspots, investigate possible correlations with documented nuclear tests, and see where your own methods take you! Are we alone on Earth, or are we witnessing the presence of another civilization? Stop waiting for governments, UAP committees, or presidents to give you the answer -- go out and find it yourself. The competition is open to individuals and teams who have not previously published research on pre-Sputnik transients. The competition is hosted and independently organized by Research Hub: researchhub.com/grant/32931/… Read more on: lostlightproject.netlify.app… @TylerDiorio @ResearchHub @BrianDoher37387 @BrianMuraresku
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Patrick Joyce retweeted
Reviewer #2: Interesting findings, but the authors failed to validate their results in an appropriate animal model
Real life, baby
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